Mukosat Injection 100mg / ml 1ml amp 10 pcs

Description

Composition
Active substance:
1 ml of solution contains: Sodium chondroitin sulfate – 100 mg.
Excipients:
Benzyl alcohol – 9 mg; Water for injections to 1 mL.
Product form:
Solution for intramuscular administration of 100 mg / ml.
1 or 2 mL neutral glass ampoules. 5 vials are placed in blisters of polyvinyl chloride film or polystyrene tape and printed lacquered aluminum foil or paper with a single layer of polyvinylidene chloride coating (foil or without coatings).
1 or 2 blisters with instructions for use placed in a pile of cardboard.
Contraindications
Hypersensitivity to the drug, a tendency to bleeding, thrombophlebitis.
Dosage
100 mg / ml
Indications
Degenerative diseases of the joints and spine: osteoarthritis, intervertebral osteochondrosis.
Interaction with other drugs
During the course of treatment with “Mukosat» ® with caution relates to the simultaneous application of direct action of anticoagulants. It is also possible potentiation of no direct anticoagulants, antiplatelet agents, and fibrinolytic agents.
pharmachologic effect
Pharmacological group:
Tissue repair promoter.
Pharmacological properties:
The drug has hondroprotektivnoe stimulating regeneration of cartilage anti-inflammatory activity. Is involved in the construction of the basic substance of cartilage and bone tissue, improves calcium-phosphorus metabolism in cartilage inhibits enzymes breaking the structure and function of articular cartilage, inhibits the degeneration of cartilage processes. Stimulates the synthesis of proteoglycans, normalizes metabolism hyaline cartilage surfaces promotes regeneration of cartilage and joint capsule. Prevents compression of the connective tissue, increases the production of synovial fluid and the mobility of the affected joints, reduces the concomitant inflammation, pain, helps reduce NSAID needs. Degenerative changes in the cartilage tissue is a means of substitution therapy. The positive effect is observed within 2-3 weeks after the start of administration. The therapeutic effect persists for a long time (3-6 months) after the end of treatment.
Pharmacokinetics:
Sodium chondroitin sulfate is readily absorbed after intramuscular administration. Already after 30 minutes it is found in blood in significant concentrations: The maximum concentration is achieved after 1 h: then its contents for 2 days gradually decreases. Sodium chondroitin sulfate is accumulated primarily in the cartilaginous tissue. The synovium is not an obstacle to its penetration into the joint cavity. 15 minutes after intramuscular injection of sodium chondroitin sulfate found in the synovial fluid, then it falls into the articular cartilage where its content reaches a maximum after 48 hours.
Pregnancy and breast-feeding
Currently, data on the use of the drug “Mukosat®” during pregnancy and lactation, and in no children.
Conditions of supply of pharmacies
On prescription.
side effects
Allergic reactions and hemorrhage at the injection site. In these cases, medication overturned.
Storage conditions
Store in a dark place at a temperature of 0 to 20 C. Keep out of reach of children.
Dosing and Administration
Preparation “Mukosat» ® intramuscularly 1 ml of a day. With good tolerance dose was increased to 2 ml, starting from the fourth injection. The course of treatment 25-30 injections. If necessary, may repeat courses after 6 months.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist