Mizol Evalar solution nar.prim-I 1% 10ml

Description

Composition
Active substance:
1 ml of solution contains: naftifine hydrochloride – 10.00 mg.
Excipients:
Propylene glycol – 50.00 mg; Ethanol (ethyl alcohol) 95% – 400.00 mg; Purified water – 475,00 mg.
Description:
The clear colorless or nearly colorless solution with an ethanol odor.
Product form:
A solution for external application of 1%.
10 ml vial.
Contraindications
Hypersensitivity to naftifine or propylene glycol.
Pregnancy and lactation (safety and efficacy have not been established).
Medication contraindicated application on the wound surface.
Carefully:
Children’s age (clinical use experience is limited).
Dosage
10 mg / ml
Indications
Fungal infections of skin and skin folds (tinea corporis, tinea inguinalis); interdigital mycosis (tinea manum, tinea pedum); Nail fungal infections (onychomycosis); Skin candidiasis; Multicolored (pityriasis) lichen; dermatomycosis (with or without itching accompanying it).
Interaction with other drugs
The interaction with other drugs has not been studied.
Overdose
In applying the drug in accordance with the instruction overdose unlikely. In case of accidental ingestion shown gastric lavage, symptomatic therapy.
pharmachologic effect
Pharmacological group:
Antifungal agent.
Pharmacodynamics:
Naftifine – antifungal agent for external use, referring to the class of allylamine. The mechanism of action is associated with inhibition of squalene epoxidase 2.3, which reduces the formation of ergosterol, a component of fungal cell walls. Active against dermatophytes such as Trichophyton, and epidermofiton mikrosporum, molds (Aspergillus spp.), Yeast (Candida spp., Pityrosporum) and other fungi (e.g., Sporothrix schenckii).
In against dermatophytes and Aspergillus acts fungicidally naftifine. With respect to the preparation of yeasts exhibits fungicidal or fungistatic activity depending on the microorganism strain. It possesses antibacterial activity against Gram-positive and Gram-negative microorganisms that can cause secondary bacterial infection. It has anti-inflammatory action, which contributes to the rapid disappearance of the symptoms of inflammation, especially pruritus.
Pharmacokinetics:
When applied topically naftifine quickly penetrates into the skin, creating a stable antifungal concentration in its various layers that can be run once a day.
Pregnancy and breast-feeding
Use of the drug Mizol Evalar during pregnancy and lactation is contraindicated (safety and efficacy naftifine in these patients has not been studied).
Conditions of supply of pharmacies
Without recipe.
side effects
In some cases, local reactions can occur: dry skin, skin redness and burning. Side effects are reversible and do not require discontinuation of treatment.
If you have marked side effects indicated in the instructions or they are compounded, or if you notice any other side effects not mentioned in the instructions, tell your doctor.
special instructions
Mizol Evalar drug is not intended for use in ophthalmology. Do not allow contact with the drug in the eye.
To achieve the required therapeutic effect exchange treatment.
Mizol Evalar effective in the treatment of fungal infections, affecting an area of ​​skin with hyperkeratosis, as well as in the areas of hair growth.
Propylene glycol, a part of the solution, may cause skin irritation; When side effects you must stop using the product and seek medical advice.
Effects on ability to drive a vehicle, the mechanism
Mizol Evalar not affect the performance of potentially hazardous activities that require high concentration and psychomotor speed reactions.
Storage conditions
At a temperature not exceeding 25 C. Keep out of reach of children.
Dosing and Administration
Outwardly.
Mizol EVALAR applied 1 time a day to the affected skin surface and its neighboring areas (approximately 1 cm of a healthy area of ​​skin around the edges of the affected area) after their thorough cleaning and drying. The duration of therapy with dermatomycosis – 2-4 weeks (if necessary – up to 8 weeks) at candidiasis – 4 weeks.
With the defeat of nails Mizol Evalar applied 2 times a day to the affected nail.
Before the first use of the drug was removed as much as possible the affected part of the nail clippers or nail file. The duration of therapy for onychomycosis – up to 6 months.
To prevent relapse, treatment should continue for at least 2 weeks after the disappearance of clinical symptoms.
If after treatment there is no improvement or there are new symptoms, you should consult with your doctor. Use drug only according to the application and in those doses which are specified in the instruction. If necessary, please consult your physician before using the drug.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist