Miramistin solution 0.01% 150ml with spray fl

Description

Composition
Active substance:
1 liter of solution contains: benzyldimethyl [3-miristoilamino) propyl] ammonium chloride monohydrate (Miramistin, recalculated to anhydrous substance) – 0.1 g ,.
Excipients:
Purified water – to 1 liter.
Description:
Colorless, clear liquid, foaming during shaking.
Product form:
Solution for topical application of 0.01%.
Polyethylene vials with applicator urological with screw-cap 50 ml, 100 ml.
50 ml polyethylene vials with applicator urological with screw cap complete with nozzle-sprayer.
Bottles of polyethylene 50 ml, 100 ml urological applicator with a screw cap complete with nozzle gynecological.
Bottles Polyethylene 100 ml 150 ml 200 ml complete with nozzle-equipped spray or a pump spray and a protective cap. Bottles 500 ml polyethylene screw cap with tamper-evident.
Each vial of 50 ml, 100 ml, 150 ml, 200 ml, 500 ml, together with instructions for use placed in a cardboard box.
For hospitals 12 bottles of 500 ml, without a pack with an equal number of instructions for use are placed in a box of paperboard for consumer packaging.
Contraindications
Individual intolerance to the drug.
Dosage
0.1 mg / ml
Indications
Otorhinolaryngology: complex treatment of acute and chronic otitis, sinusitis, tonsillitis, laryngitis, pharyngitis.
For children aged 3 to 14 years is used for complex treatment of acute pharyngitis and / or exacerbation of chronic tonsillitis.
Dental treatment and prevention of infectious and inflammatory diseases of the oral cavity: stomatitis, gingivitis, periodontitis, periodontitis. Hygienic handling of removable dentures.
Surgery, Traumatology: suppurations prophylaxis and treatment of purulent wounds. Treatment of chronic inflammatory processes of the musculoskeletal system.
Obstetrics, Gynecology: prevention and treatment of suppuration postpartum traumas, wounds vagina and perineum, obstetric infections, inflammatory diseases (vulvovaginitis, endometritis).
Combustiology: Treatment of superficial and deep burns II and IIIA degree burn wounds to prepare dermatoplastike.
Dermatology, venerology treatment and prevention pyoderma and tinea, candidiasis of the skin and mucous membranes, mycosis stop.
Individual prevention of diseases, sexually transmitted diseases (syphilis, gonorrhea, chlamydia, trichomoniasis, genital herpes, genital candidiasis, etc.).
Urology: complex treatment of acute and chronic urethritis and uretroprostatitis specific (chlamydia, trichomoniasis, gonorrhea) and non-specific nature.
Interaction with other drugs
While the use of antibiotics, it is noted enhance their antibacterial and antifungal properties.
pharmachologic effect
Pharmacological group:
Antiseptic.
Pharmacological properties:
Miramistin has a broad spectrum of antimicrobial activity, including hospital strains resistant to antibiotics.
The drug has a marked bactericidal activity against Gram-positive (Staphylococcusspp., Streptococcusspp., Streptococcuspneumoniae et al.), Gram (Pseudomonasaeruginosa, Escherichiacoli, Klebsiellaspp. Et al.), Aerobic and anaerobic bacteria, determined as monocultures and microbial associations including hospital strains with multidrug-resistant to antibiotics.
It has antifungal activity on Aspergillus genus Ascomycetes and the genus Penicillium, the yeast (Rhodotorula rubra, Torulopsis gabrata etc.), and yeast-like fungi (Candida albicans, Candida tropicalis, Candida krusei, Pityrosporum orbiculare (Malassezia furfur), etc.) dermatophytes (Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton verrucosum, Trichophyton schoenleini, Trichophyton violacent, Epidermophyton Kaufman-Wolf, Epidermophyton floccosum, Microsporum gypseum, Microsporum canis, etc.), as well as others. pathogenic fungi as monocultures and microbial associations including fungal microflora with resistance to chemotherapeutic drugs.
It has antiviral effect, active against multi-structured viruses (herpes viruses, human immunodeficiency virus, and others.).
Miramistin acts on pathogens, sexually transmitted diseases (Chlamydiaspp., Treponemaspp., Trichomonasvaginalis, Neisseriagonorrhoeae et al.).
Effectively prevent infection of wounds and burns. Activates regeneration processes. Stimulates the protective reaction at the site of application, due to activation of the absorption and digestive functions of phagocytes, potentiates the activity of monocyte-macrophage system. Has pronounced hyperosmolar activity, thereby suppresses the wound and perifocal inflammation, absorbs purulent exudate, contributing to the formation of dry crust. Does not damage the granulation and viable skin cells, it does not inhibit the edge epithelialization.
It has no locally-irritant and allergenic properties.
Pharmacokinetics:
The local application has the ability miramistin not absorbed through the skin and mucous membranes.
Conditions of supply of pharmacies
Without recipe.
side effects
In some cases, the application site may feel light burning, which takes place on their own, after 15-20 seconds, and do not require discontinuation of therapy. Allergic reactions.
Storage conditions
Store at a temperature not higher than 25 C.
Keep out of the reach of children.
Dosing and Administration
The preparation is ready for use.
For instructions on using the package with a nozzle spray:
1. Remove the cap from the vial, a vial with 50 ml remove as urological applicator.
2. Remove the attached spray nozzle of the pouch.
3. Attach spray nozzle to the bottle.
4. Activate the spray nozzle pressing.
Instructions for use of the package 50 ml or 100 ml with a gynecological nozzle:
1. Remove the cap from the bottle.
2. Remove the attached gynecological attachment from its protective packaging.
3. Attach gynecological attachment to the bottle without removing the applicator urological.
Otorhinolaryngology.
Purulent sinusitis – when puncture the maxillary sinus is washed with a sufficient amount of the drug.
Tonsillitis, pharyngitis and laryngitis treated gargling and / or irrigation through the spray nozzle, 3-4-x fold by pressing 3-4 times a day. The amount of drug per rinse 10-15 ml.
In children. In acute pharyngitis and / or exacerbation of chronic tonsillitis carried pharynx irrigation using a spray nozzle. Children aged 3-6 years: a single press on the head of the spray nozzle (3-5 ml per irrigation), 3-4 times a day; children aged 7-14 years old two-time pressing (5-7 ml per irrigation), 3-4 times a day; children over 14 years 3-4 fold by pressing (10-15 ml per irrigation), 3-4 times a day. Duration of therapy is from 4 to 10 days depending on the timing of the onset of remission.
Dentistry.
When stomatitis, gingivitis, periodontitis recommended oral rinse formulation 10-15 ml, 3-4 times a day.
Surgery, traumatology, combustiology.
C prophylactic and therapeutic purposes irrigate the surface of wounds and burns and loosely wound tamponiruyut tracts, fixed gauze sponges soaked drug. Medical procedure is repeated 2-3 times a day for 3-5 days. Highly active wound drainage method and cavities with daily flows up to 1 liter of the preparation.
Obstetrics, Gynecology.
In order to prevent postpartum infection is applied in the form of vaginal irrigations before delivery (5-7 days), after each delivery vaginal examination and postpartum 50 ml of the product as a tampon with an exposure of 2 hours, for 5 days. the use of gynecological attachments are recommended for the convenience of vaginal irrigation. The contents of the vial with a gynecological nozzle inserted into the vagina and make irrigation.
Women during delivery by caesarean section, immediately before surgery treated vagina during surgery – uterine cavity and the incision therein and postoperatively administered tampons wetted preparation in the vagina with an exposure for 2 hours for 7 days. Treatment of inflammatory diseases is carried out during the course of 2 weeks by administration of intravaginal tampons with a drug, as well as by iontophoresis.
Venereology.
For the prevention of sexually transmitted diseases drug effective when it is applied not later than 2 hours after intercourse. The contents of the vial with a urology applicator enter into the urethra of 2-3 m: male (2-3 ml) women (1-2 ml) and the vagina (5-10 ml). For convenience, we recommend the use of a gynecological attachment. Treat skin inner thighs, pubic area, genitals. After the procedure is recommended not to urinate for 2 hours.
Urology.
The combined treatment of urethritis and uretroprostatitis injection into the urethra is carried out with 2-3 ml of the preparation 1-2 times a day course – 10 days.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist