Mezim forte 20tabs (Mezym forte)

Description

Composition
Active substance:
1 tablet contains:
Pancreatin * with a minimum: lipolytic activity – 3500 IU Ph.
Eur. amylolytic activity – 4200 IU Ph.
Eur. total proteolytic activity – 250 IU Ph.
Eur. * Obtained from pig pancreas.
Excipients:
Microcrystalline cellulose, sodium carboxymethyl starch (type A), colloidal silicon dioxide, magnesium stearate. sheath: talc, hypromellose, azorubinovy ​​lacquer (E 122) Simethicone emulsion 30% (dry weight), a polyacrylate dispersion 30% (dry weight), titanium dioxide (E 171), macrogol 6000.
Description:
Pink Valium tablets, coated with an almost plane-parallel surfaces and beveled edges, with the characteristic odor of pancreatin.
Product form:
Film-coated tablets.
20 tablets in blisters (blister) PVC / aluminum foil, or PVC / PE / PVDC / Aluminum foil.
1, 2.4 or 5 blisters with instructions for use in a cardboard package.
Contraindications
Increased sensitivity to the drug. acute pancreatitis or acute exacerbation of chronic pancreatitis. children up to 3 years (for a given dosage form).
Indications
Insufficiency of exocrine pancreatic function (chronic pancreatitis, cystic fibrosis, and so forth.) Chronic inflammatory-degenerative diseases of the stomach, intestines, liver, gallbladder. state after resection or irradiation of these organs accompanied by disturbances of digestion of food, flatulence, diarrhea (in combination therapy). to improve food digestion in patients with normal function of the gastrointestinal tract in the case of errors in the diet. preparations for X-ray and ultrasound examination of the abdominal cavity.
Interaction with other drugs
Possible reduction of folic acid intake during the simultaneous use of preparations containing pancreatin. The effect of hypoglycemic agents for oral administration (acarbose, miglitol) can be reduced while the use of digestive enzymes, containing the pancreatic enzymes that cleave carbohydrates (e.g., amylase).
Overdose
Cases of overdose have not been marked.
pharmachologic effect
Pharmacological group:
Digestive enzymatic means.
Pharmacological properties:
Pancreatin is a powder of porcine pancreatic glands. Pancreatic enzymes are part of the pancreatin have proteolytic, amylolytic and lipolytic effect and contribute to the breakdown of proteins, fats, carbohydrates, improve the functional state of the gastrointestinal tract (GIT), thereby normalizing the digestion processes.
Pregnancy and breast-feeding
Data on the use of pancreatin during pregnancy and lactation are not available.
During pregnancy and breastfeeding period, the appointment of doctor Pancreatin is possible only if the expected benefit to the mother outweighs the potential risk to the fetus or child.
Conditions of supply of pharmacies
Without a prescription.
side effects
Possible side effects are listed below in descending frequency of occurrence: very often (> 1/10), often (> 1/100, 1/1000, 1/10000,
Violations by the immune system
Very rare: immediate type allergic reactions.
Disorders of the gastrointestinal tract
Very rare: diarrhea, abdominal discomfort, nausea, vomiting; stricture formation in ileocecal and ascending sections of the colon in patients with cystic fibrosis with high doses of pancreatin.
Violations of the urogenital system
Frequency unknown: hyperuricosuria (see “Special Instructions” section.).
special instructions
Patients with cystic fibrosis, especially when high doses of pancreatin may hyperuricosuria occur, so this group of patients is necessary to control the concentration of uric acid in urine.
In the above group of patients described cases of the formation of strictures in the ileocecal and ascending part of the colon. As a precaution when a unfamiliar abdominal discomfort or change the nature of complaints, particularly when high doses of more than 10,000 units lipase / kg per day, it is necessary medical examination.
Effect on ability to drive vehicles and other mechanisms:
The drug Mezim fort have no or negligible influence on the ability to drive vehicles and mechanisms.
Storage conditions
Store at a temperature not higher than 25 C. Keep out of reach of children !.
Dosing and Administration
Dose Mezim® forte is determined individually depending on the degree of digestion.
Adults: 1 – 2 tablets before meal inside liquid squeezed water (Mezim® drug efficacy may be reduced forte chewiness and pancreatic enzymes when released can irritate the oral mucosa).
If necessary, additional food during take another 2 – 4 tablets.
In the case where higher dosages are required pancreatin need for medical consultation purpose other enzyme preparations with higher dosages (e.g., a drug Mezim® forte Mezim® 10000 or 20000), depending on symptoms (e.g., reducing the severity of steatorrhea, abdominal pain ).
Duration of treatment may vary from a few days (in violation of digestion due to errors in the diet) to several months or even years (permanent replacement therapy if necessary).
In children, the drug is used by a physician.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist