Metronidazole tab 500mg 20 pieces of ozone

Description

Composition
Active substance:
1 tablet contains: Metronidazole 500 mg or 250 mg.
Product form:
Tablets of 250 mg or 500 mg. 10, 20 tablets in blisters of PVC film and aluminum foil printed patent. 10, 20, 30, 40, 50, 60 or 100 tablets per plastic jars for medicaments. One jar or 1, 2, 3, 4, 5, 6, 8 or 10 contour of cellular packaging together with instructions for use placed in a cardboard box (pack).
Contraindications
Hypersensitivity, leukopenia (including history), organic CNS (including epilepsy), hepatic failure (in the case of large doses destination), pregnancy (I term), lactation.
Precautions – Pregnancy (II-III trimesters), renal / hepatic failure.
Dosage
500 mg
Indications
Protozoal Infection: extraintestinal amebiasis, including amebic liver abscess, intestinal amoebiasis (amoebic dysentery), trichomoniasis, giardiazis, balantidiasis, giardiasis, cutaneous leishmaniasis, Trichomonas vaginitis, urethritis Trichomonas. Infections caused by Bacteroides spp. (Including B. fragilis, B. distasonis, B. ovatus, B. thetaiotaomicron, B. vulgatus): bone and joint infections, infections of the central nervous system (CNS), including: meningitis, brain abscess, bacterial endocarditis, pneumonia, empyema and lung abscess. Infections caused by species of Bacteroides, including the group of B. fragilis, species Clostridium, Peptococcus and Peptostreptococcus: abdominal infections (peritonitis, liver abscess), pelvic infections (endometritis, endomyometritis, abscess, fallopian tubes and ovaries, vaginal cuff infections after surgery) , skin and soft tissue infections. Infections caused by Bacteroides species, including the group B. Fragilis and species Clostridium: sepsis. Pseudomembranous colitis (involving the use of antibiotics). Gastritis or duodenal ulcer associated with Helicobacter pylori, alcoholism. Prevention of postoperative complications (especially interventions on the colon, okolorektalnoy area apendektomiya, gynecologic surgery). Radiotherapy patients with tumors – as radiosensitizing agents in cases where the resistance of the tumor is caused by hypoxia in the tumor cells.
pharmachologic effect
Pharmacological group:
Antimicrobial and protivoprotozoynoe means.
Pharmacological properties:
Antiprotozoal and antimicrobial drug, derivative, 5-nitroimidazole. The mechanism of action is in the biochemical reduction of 5-nitro intracellular transport proteins of anaerobic microorganisms and protozoa recovered 5-nitro reacted with deoxyribonucleic acid (DNA) microbial cells by inhibiting synthesis of nucleic acids, which leads to the death of the bacteria. Active against Trihomonas vaginalis, Entamoeba histolica, Gardnerella vaginalis, Giardia intestinalis, Lamblia spp., As well as obligate anaerobes Bacteroides spp. (Including Bacteroides fragilis, Bacteroides distasonis, Bacteroides ovatus, Bacteroides thetaiotaomicron, Bacteroides vulgatus), Fusobacterium spp., Veillonela spp., Prevotella (P. bivia, P / buccae, P / disiens), and some gram-positive bacteria ( Eubacterium spp., Clotridium spp., Peptococcus spp., Peptostreptococcus spp.). Minimum inhibitory concentration for these strains is 0.125-6.25 g / ml. In combination with amoxicillin is active against Helicobacter pylori (Amoxicillin inhibits the development of resistance to metronidazole). Not sensitive to metronidazole aerobic microorganisms and facultative anaerobes, but in the presence of mixed flora (aerobes and anaerobes) Metronidazole acts synergistically with antibiotics effective against common aerobes. Increases of tumor sensitivity to radiation, causes sensitization to alcohol (disulfiramopodobnyh action), stimulates repair processes.
Conditions of supply of pharmacies
Prescription.
Storage conditions
Store in a dark place at a temperature not higher than 25 C.
Dosing and Administration
Inside, during or after a meal (or drinking milk), not liquid.
If trichomoniasis – 250 mg 2 times a day for 10 days or 400 mg 2 times a day for 5-8 days.
Women must additionally assign metronidazole in the form of vaginal suppositories or tablets. If necessary, it is possible to repeat the course of treatment or to increase the dose of 0.75-1 g / day. should make a break between courses of 3-4 weeks to conduct repeated control laboratory tests.
An alternative scheme is to assign therapy to 2 g once the patient and his sex partner.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist