Metformin 500mg tab 60 pcs ozone

$3.13

Metformin 500mg tab 60 pcs ozone

Quantity:

SKU: 0220051850 Categories: , , Tags: ,

Description

Composition
Active substance:
1 tablet contains: metformin hydrochloride – 500 mg or 850 mg or 1000 mg.
Product form:
The tablets of 500, 850 and 1000 mg. 10, 20 tablets in blisters of PVC film and aluminum foil printed patent. 10, 20, 30, 40, 50, 60, 80, 100 or 120 tablets per plastic jars for medicaments. One jar or 1, 2, 3, 4, 5, 6, 8, 10 or 12 contour cell packages together with instructions for use placed in a cardboard box (pack).
Contraindications
Hypersensitivity to metformin or any auxiliary substance; diabetic ketoacidosis, diabetic precoma, coma; renal failure or renal dysfunction (creatinine clearance (CC) of less than 60 ml / min); acute conditions occurring at risk for renal dysfunction: dehydration (diarrhea, vomiting), severe infectious disease, shock; symptomatic manifestations of acute or chronic disease that may lead to the development of tissue hypoxia (including cardiac or respiratory failure, acute myocardial infarction); extensive surgery and trauma when shown holding insulin; hepatic failure, liver dysfunction; chronic alcoholism, acute alcohol poisoning; pregnancy; lactic acidosis (including history); application in less than 48 hours before and 48 hours after the radioisotope or radiological examinations with the introduction iodinated contrast material; observance of a low calorie diet (less than 1000 kcal / day); Children up to age 10 years.
Dosage
500 mg
Indications
Type 2 diabetes, especially in obese patients with poor diet and exercise: adults as monotherapy or in combination with other oral hypoglycemic agents or insulin; children from 10 years as monotherapy or in combination with insulin.
pharmachologic effect
Pharmacological group:
Group biguanide hypoglycemic agent for oral use.
Pharmacological properties:
Metformin reduces hyperglycemia without causing hypoglycemia. Unlike sulfonylureas, it does not stimulate insulin secretion and does not have a hypoglycemic effect in healthy individuals. Peripheral receptors increases the sensitivity to insulin and disposal of glucose by cells. Inhibits gluconeogenesis in the liver. Delays the absorption of carbohydrates in the intestines. Metformin stimulates glycogen synthesis by acting on glycogen synthase. Increases the transport capacity of all types of membrane glucose transporters. Moreover, it has a beneficial effect on lipid metabolism: reduces total cholesterol, LDL and triglycerides. On metformin patient body weight either remains stable or moderately reduced.
Conditions of supply of pharmacies
Prescription.
Dosing and Administration
The tablets should be taken orally, swallowed whole without chewing, during or immediately after a meal, drinking plenty of water. Adults: monotherapy and combination therapy in combination with other oral hypoglycemic agents: The usual initial dose is 500 mg or 850 mg 2-3 times a day, during or after meals. Perhaps a further gradual increase in dose, depending on the concentration of glucose in the blood. Maintenance dose is typically 1500-2000 mg / day. To reduce the side effects from the gastrointestinal tract daily dose should be divided into 2-3 doses. The maximum dose of 3000 mg / day divided into three doses. The slow increase in the dose may improve gastrointestinal tolerability. Patients receiving metformin in doses of 2000-3000 mg / day may be transferred to receiving 1000 mg of the drug. The maximum recommended dose is 3000 mg / day, divided into 3 doses. In the case of transition planning with the reception of other hypoglycemic agents: it is necessary to stop taking other means and start receiving the drug Metformin dosage, above. Combination with insulin: to achieve better control of blood glucose, metformin and insulin may be used as combination therapy. The usual starting dose of metformin 500 mg or 850 mg of one tablet 2-3 times a day, the drug Metformin 1000 mg – 1 one tablet once a day, while the dose of insulin is selected based on the blood glucose concentration. Children and adolescents: children from 10 years of age the drug Metformin may be used as monotherapy or in combination with insulin. The usual initial dose is 500 mg or 850 mg 1 time per day after or during meals. After 10-15 days, the dose should be adjusted based on the concentration of blood glucose. The maximum daily dose is 2000 mg, divided into 2-3 doses. Elderly: due to a possible reduction in the dose of metformin renal function should be selected under the supervision of regular indicators of renal function (creatinine determine the concentration of at least 2-4 times in the blood serum of a year). The duration of treatment determined by the doctor. Not recommended termination of the drug without a doctor.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg
Manufacturer

OZONE generics

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