Makmiror tab n / about 20 pcs 200mg

Description

Composition
Active substance:
nifuratel 200.00 mg;
Excipients:
60,00 mg starch maize, rice starch 5.00 mg macrogol 6000 (polyethylene glycol-6000) 15.00 mg talc 30.00 mg magnesium stearate 2.50 mg, 2.30 mg of gelatin, acacia gum (gum arabic ) 2.30 mg;
Coating: Sucrose 150.00 mg 33.00 mg magnesium carbonate, titanium dioxide 0.90 mg, 0.30 mg wax.
Description:
Round biconvex tablets, coated white
Product form:
Coated tablets of 200 mg.
10 tablets in blister PVC / aluminum foil.
2 blister with instructions for use placed in a cardboard box.
Contraindications
Hypersensitivity to the active ingredient or any component of the formulation.
Deficiency of sucrose / isomaltose, fructose intolerance, glucose-galactose malabsorption.
Dosage
200 mg
Indications
Vulvovaginal infections caused by susceptible to malaria pathogens (pathogens, fungi of the genus Candida, Trichomonas, bacteria, chlamydia).
Pyelonephritis, urethritis, cystitis, pyelitis and other diseases of the urinary system.
Intestinal amebiasis and giardiasis.
Chronic inflammatory diseases of the upper gastrointestinal tract associated with infection Helicobacter pilory.
Interaction with other drugs
It enhances the antifungal activity of nystatin.
Overdose
Cases of overdose were observed.
pharmachologic effect
Pharmacological group:
an antimicrobial agent and protivoprotozoynoe -nitrofuran.
Pharmacodynamics:
Nifuratel – antimicrobial agent from the group of nitrofurans; It has protivoprotozoynoe, antifungal and antibacterial properties.
Nifuratel has high efficiency and low toxicity that causes a wide spectrum of its clinical use.
Highly effective against Papiliobacter and Helicobacter pylori, Gram-positive and Gram-negative microorganisms.
The spectrum of action includes: Enterococcus faecalis, Enterococcus faecium, Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Shigella flexneri 2a, Shigella flexneri 6, Shigella sonnei, Salmonella typhi, Salmonella typhimurium, Salmonella enteridis, Klebsiella spp, Enterobacter sph, Serratia spp… , Citrobacter spp., Morganella spp., Rettgerella spp., Pragia
fontium, Budvicia aquatica, Rachnella aquatilis and Acinetobacter spp, atypical other enterobacteriaceae as well as protozoa (Trichomonas, amoeba, giardia).; less active against Proteus mirabilis, Proteus vulgaris, Pseudomonas aeruginosa.
The drug of choice for the treatment of salmonellosis, shigellosis, and others. Acute intestinal bacterial infections.
It is active against Trichomonas vaginalis, is highly active against fungi of the genus Candida.
Particularly effective against Helicobacter pylori strains resistant to metronidazole
Pharmacokinetics:
If ingestion is rapidly absorbed from the gastrointestinal tract. Penetrates the blood-brain barrier and gematoplatsentarny, is excreted in breast milk.
It is metabolized in the liver and muscle. Completely excreted by the kidneys (30-50% unchanged) exerting a strong antibacterial effect in the urinary tract.
Pregnancy and breast-feeding
Nifuratel gematoplatsentarny penetrates the barrier, so the use of the drug is possible only under strict conditions, if the effect of therapy outweighs the potential risk to the fetus.
Nifuratel excreted into breast milk, so if necessary, the appointment during lactation should decide the issue of termination of breastfeeding.
Conditions of supply of pharmacies
Prescription
side effects
Dyspepsia: nausea, vomiting, bitter taste in the mouth, diarrhea, heartburn.
Allergic reactions: skin rash, itching.
special instructions
In the treatment of vaginal infections only performing oral therapy
Makmiror, it is recommended to increase the daily dosage of the drug to 4-6 tablets.
During the period of treatment should refrain from sexual intercourse.
Effects on ability to drive a car or other mechanisms:
The drug has no effect on the ability to drive vehicles and engage in potentially hazardous activities that require high concentration and psychomotor speed reactions.
Storage conditions
In the dark place at a temperature not higher than 25 ° C.
Keep out of the reach of children!
Dosing and Administration
The drug is taken orally following the recommendations.
Vaginal infections:
Adults: 1 tablet 3 times a day after meals for 7 days (taking the drug should both sexual partners).
Children: The recommended dose of 10 mg / kg body weight daily for 10 days.
The recommended dose should be taken in two doses.
Urinary tract infections:
Adults: depending on severity of disease 1-2 tablets three times a day for 7-14 days.
Children: The recommended dose of 30-60 mg / kg body weight. The recommended dose should be taken in two doses.
On the recommendation of the physician treatment of urinary tract infections may be prolonged or repeated.
Intestinal amebiasis:
Adults: 2 tablets 2-3 times a day for 10 days.
Children: The recommended dose of 10 mg / kg body weight 3 times per day.
giardiasis:
Adults: 2 tablets 2-3 times a day for 7 days.
Children: The recommended dose of 15 mg / kg of body weight, 2 times a day for 7 days.
Inflammatory diseases of the upper gastrointestinal tract,
associated with Helicobacter pylori:
Adults: 2 tablets 2-3 times a day for 7 days.
Children: The recommended dose of 15 mg / kg of body weight, 2 times a day for 7 days.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist