Makmiror complex 500 cream vaginas. 30g tube

Description

Composition Active ingredient: nifuratel 10.00 g + nystatin 4000 000,0 ME Excipients: 15 ksalifin 10.00 g, 0.11 g of methyl parahydroxybenzoate, propyl parahydroxybenzoate 0.04 g, glycerol (glycerin) 5,00 g of sorbitol solution 70% 10.00 g, 5.00 g propylene glycol, carbomer 0.40 g, 30% triethanolamine 1.50 g purified water to 100.00 g Description: A liquid, homogeneous cream yellow Product: vaginal cream: 30 g the drug in an aluminum tube. 1 and an applicator tube (graduated syringe) with instructions for use placed in a cardboard box. Hypersensitivity to nifuratel, nystatin or any excipient the formulation. Indications for use of vulvovaginal infection caused by sensitive pathogens, including bacterial vaginosis, trichomoniasis of the vagina; vaginitis, caused by fungi of the genus Candida, mixed vaginitis. Interaction with other drugs not identified clinically significant drug interactions Makmiror complex with other drugs. Overdose Cases of overdose have been reported. Pharmacological Therapeutic effect: combined means (protivoprotozoynoe antimicrobial and antifungal agent +) Code: G01AH Pharmacodynamics: Antimicrobial agent for topical application. It has protivoprotozoynoe, antifungal and antibacterial properties. Nifuratel, nitrofuran derivative. Highly active against a number of bacteria, fungi and protozoa (including Trichomonas vaginalis). Nystatin – antifungal antibiotic polyenes group. By binding to sterols in the cell membrane of fungi, violates its permeability, which leads to cell death. Highly active against Candida albicans. Nifuratel and nystatin combination allows to achieve a more pronounced antifungal activity and greatly expand the range of antimicrobial action. High efficiency and low toxicity of the components of the drug are responsible for a wide range of its clinical application in the treatment of vaginitis of mixed etiology, in particular the use for the prevention of fungal infections caused by specific treatment of trichomoniasis. Makmiror complex does not violate the physiological flora, thus avoiding the development of dysbiosis and quickly restore normotsenoz vagina. Pharmacokinetics: The studies confirm that vaginal application in animals (rabbit and dog) with repeated administration of the daily dose, which is 30 times the therapeutic dose of substance, are part of the drug is not absorbed into the bloodstream and do not have a systemic action. Pharmacokinetics studies have not been conducted in humans. Pregnancy and lactation Use of the drug during pregnancy is possible if the potential benefit to the mother outweighs the risk to the fetus or child. During treatment it is necessary to resolve the issue of termination of breastfeeding. from pharmacy dispensing conditions Prescription Side effects possible allergic reactions such as skin rash or itching. With the development of allergic reactions, use of the drug should be discontinued. Specific guidance is necessary to conduct simultaneous treatment of sexual partners at risk of re-infection. In the period of treatment should avoid sexual contact. Effect on the ability to drive, mechanisms for use of the drug does not affect the ability to drive vehicles, and other activities requiring increased attention. Effects on ability truck control mechanisms and use of the drug does not affect the ability to drive vehicles and other activities that require attention. Storage conditions in the dark place at a temperature not higher than 25 ° C. Keep out of the reach of children! Dosing and dose Intravaginal 2.5 g cream once or twice a day, morning or evening, according to the doctor’s recommendations for 8 days. The required dose of cream to be administered using a graduated applicator. Instructions for use of the graduated applicator: Screw graduated applicator tube of cream. Collect the necessary amount of cream (in accordance with scale lines, denotes the number of grams), pressing on the tube. Disconnect from the tube inserted into the vagina, squeeze out the contents of the applicator, pushing the rod. The presence of a special nozzle allows the introduction of a cream, without damaging the hymen. To do this, remove the cannula from the top of the rod and screw on the syringe head to the other side before you enter the cream into the vagina. Info appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist To do this, remove the cannula from the top of the rod and screw on the syringe head to the other side before you enter the cream into the vagina. Info appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist To do this, remove the cannula from the top of the rod and screw on the syringe head to the other side before you enter the cream into the vagina. Info appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist