Magnesium diasporal prig.rastvora granules for oral 300mg / 5g bags 20 pcs

Description

Composition
Active substance:
1 sachet contains: magnesium citrate, 1830.0 mg, equivalent to 295.7 mg of magnesium content.
Excipients:
Sucrose – 2341.2 mg Citric Acid – 660.0 mg Sodium bicarbonate 145.0 mg Orange flavoring – 22.3 mg, riboflavin (E101) – 1.5 mg.
Description:
The mixture of pellets of irregular shape, and a yellow powder.
Product form:
Granules for oral solution.
5,0 g packet of the composite material (paper, aluminum foil, plastic film). SP2 connected heat seal seam. According to the package 2 are connected with the applied heat seal seam text instructions, individually or packages 20 or 50 together with instructions for use in a cardboard box.
Contraindications
Individual hypersensitivity to the drug, severe renal failure, atrioventricular block, myasthenia gravis, gipermagniemiya, children under 12 years.
Due to the presence of sucrose in the formulation Magnesium Diasporal® 300 contraindicated in fructose intolerance, malabsorption syndrome glucose or galactose deficiency or sucrase – isomaltase.
Carefully
Moderate renal failure (risk of gipermagniemii).
Dosage
300 mg
Indications
Magnesium deficiency is accompanied by symptoms such as: minor sleep disturbances, irritability, mild anxiety, fatigue, spasms of the calf muscles.
Interaction with other drugs
Aminoglycoside antibiotics, cisplatin and cyclosporine accelerate the excretion of magnesium.
magnesium ions, iron, fluoride, and tetracycline, mutually influence on the absorption of each other, so it is necessary to observe 2 – 3 hour interval between reception Magnesium Diasporal® 300 and drugs containing the above agents.
Magnesium reduces the effect of indirect anticoagulants, reduces the absorption of iron. Simultaneous application of preparations containing phosphate or calcium salts, can significantly reduce the magnesium absorption in the gastrointestinal tract.
Overdose
In normal renal function receiving oral magnesium does not cause toxic reactions. Only the alleged symptoms may occur against a background of severe renal insufficiency.
Overdose symptoms: decrease in blood pressure, nausea, vomiting, diminished reflexes, respiratory depression, coma, heart failure, anuria.
Treatment: Intravenous administration of calcium, and intramuscular or subcutaneous injection vials 1-2 (0.5-1 mg / ml) neostigmine; intravenous or oral administration of 0.9% sodium chloride; in the case of kidney failure – peritoneal dialysis or hemodialysis.
pharmachologic effect
Pharmacological group:
Magnesium preparation.
Pharmacological properties:
Magnesium is involved in many metabolic reactions, it activates more than 300 enzymes. An indispensable element in processes providing intake and energy expenditure. Participates in the balance of electrolytes, ion transport, membrane permeability, in the transmission of nerve impulses and regulating muscle contraction. It is a natural antagonist of calcium.
Pharmacokinetics:
Magnesium slowly and incompletely absorbed in the gastrointestinal tract in syndrome of malabsorption and use of food rich in fats, magnesium absorption decreases. The unabsorbed portion of magnesium excreted through the intestines.
The serum contains about 1% of adsorbed magnesium (0,8-1,0mmol / l). Approximately 45% of magnesium binds to intracellular proteins and energy-rich phosphates and deposited in skeletal muscle, kidney, liver and myocardium. The remaining part is deposited into bone tissue; in small quantities, in the tissue fluid and red blood cells.
Magnesium ions penetrate the blood-brain barrier and the placental barrier.
Absorbed magnesium is eliminated by the kidneys, and only a small fraction is excreted in the bile and through the sweat glands.
Partially resorbed in the renal tubules. rate of excretion by the kidneys is proportional to the plasma concentration and glomerular filtration of magnitude.
Pregnancy and breast-feeding
Use of the drug during pregnancy only on the advice of a doctor. Taking into account that magnesium gets into breast milk, it is recommended to stop feeding if necessary dose.
Conditions of supply of pharmacies
On prescription.
side effects
Allergic reactions, disorders of the gastrointestinal tract: diarrhea, abdominal pain, constipation, nausea, bloating.
special instructions
The drug has no effect on machines and mechanisms management ability.
Storage conditions
Store at a temperature of from 15 to 25 ° C.
Keep out of the reach of children!.
Dosing and Administration
Inside.
Adults and children over 12 years, 1 packet daily. Dissolve the contents of 1 package in 1/2 cup of fruit juice, tea or water. The average duration of treatment is 1 month. Treatment should be discontinued after the normalization of the level of magnesium in the blood.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist