Magnemaks tab 500mg 20 pieces

Description

Composition
Active substance:
Magnesium orotate dihydrate 500 mg ;.
Excipients:
Lactose monohydrate, corn starch, microcrystalline cellulose, povidone K-30, sodium croscarmellose, colloidal silicon dioxide (Aerosil), sodium cyclamate, talc, magnesium stearate.
Description:
Round Valium tablets white or nearly white with a facet and Valium.
Product form:
Tablets of 500 mg.
10 tablets in blisters of PVC film and aluminum foil printed patent.
1, 2, 3, 5, 10 contour cell packages together with instructions for use placed in a pile of cardboard.
Contraindications
Increased sensitivity to the drug, urolithiasis, renal dysfunction, a predisposition to the formation of calcium-magnesium-ammonium-phosphate stones, cirrhosis with ascites.
Children up to age 18 years.
The preparation contains lactose, so it should not be used for patients with lactose intolerance, lactase deficiency or glucose-galactose malabsorption.
Dosage
500 mg
Indications
Established magnesium deficiency, isolated or associated with other deficiency states, accompanied by symptoms such as irritability, minor sleep disturbances, gastrointestinal spasms, fatigue, pain, and muscle spasms, tingling sensation in the muscles. If after a month of treatment there is no reduction in these symptoms, continued treatment is inappropriate.
Interaction with other drugs
When simultaneous administration of magnesium preparations with iron preparations, sodium fluoride and tetracyclines may reduce the absorption of the latter. Furthermore, aminoquinolines, quinidine, penicillamine should not be administered concurrently with magnesium preparations. Therefore, these drugs should be taken with an interval of 2-3 hours.
Oral contraceptives, diuretics, muscle relaxants, glucocorticoids, insulin, reduce the effect of the drug.
Magnesium should be used with caution if you are taking magnesium-containing medications such as antacids or laxatives, or potassium-sparing diuretics or medications containing calcium. While the use of preparations containing aluminum, the aluminum may be increased in the absorption body.
Magnesium should be used with caution while the use of digitalis preparations, since simultaneous application can interfere with the absorption of digitalis preparations.
Some antibiotics (aminoglycosides), cisplatin and cyclosporin A can lead to increased excretion of magnesium.
Some diuretics (furosemide and thiazides), erlotinib and cetuximab, proton pump inhibitors (omeprozol and pantoprazole), foscarnet, pentamidine, rapamycin and amphotericin B may cause a magnesium deficiency, and thus, result in decreased drug effect.
Overdose
In normal renal function receiving magnesium inside does not cause toxic reactions. Magnesium poisoning may occur in patients with renal insufficiency. Toxic effects are mainly dependent on the magnesium concentration in the blood serum.
Symptoms: reduced blood pressure, nausea, vomiting, depression, diminished reflexes, respiratory depression, coma, cardiac arrest, anurichesky syndrome.
Treatment: Rehydration, forced diuresis. In renal failure requires dialysis or peritoneal dialysis.
pharmachologic effect
Pharmacological group:
The preparation of magnesium.
Pharmacodynamics:
The preparation of magnesium. Magnesium is an essential trace element, is involved in more than 300 enzymatic reactions regulating cell permeability and neuromuscular excitability. Necessary to ensure the many energy processes involved in the metabolism of proteins, fats, carbohydrates and nucleic acids. Magnesium exerts kurarepodobnymi closure effect on cholinergic neurons, with reduction of acetylcholine release. Magnesium and calcium in the body is partially interact synergistically: nevertheless, in the competitive inhibition of calcium and magnesium can also affect the binding sites as “physiological calcium antagonist.”
Pharmacokinetics:
It absorbed approximately 35-40% of the dose. Hypomagnesaemia stimulates absorption of magnesium ions. The presence of orotic acid salts of magnesium improves the absorption.
Magnesium is excreted by the kidneys, excretion decreases with magnesium deficiency and increased when it is excess.
Pregnancy and breast-feeding
It can be used during pregnancy only on the advice of a doctor. Magnesium is excreted in breast milk. It should avoid the use of the drug during breastfeeding.
Use of the drug during pregnancy and lactation is possible if the potential benefit to the mother outweighs the potential risk to the fetus and child.
Conditions of supply of pharmacies
Without a prescription.
side effects
On the part of the gastrointestinal tract: an unstable chair, and diarrhea, which usually runs alone at lower dose.
Immune system: allergic reactions.
special instructions
The preparation contains lactose monohydrate, therefore, its use is not recommended for patients with hereditary galactosemia, malabsorption syndrome glucose and galactose and lactase deficiency.
Effect on ability to drive and use machines The drug does not affect the ability to drive vehicles, mechanisms and engage in other activities that require high concentration and speed of psychomotor reactions.
Storage conditions
At temperatures above 25 ° C.
Keep out of the reach of children.
Dosing and Administration
Inside, before meals with a little liquid.
Assign 2 tablets 3 times a day for 7 days, then – 1 tablet 2-3 times daily. Duration of treatment – 4 weeks.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist