Lugol solution with glycerol solution mest.pr. 25ml vial

Description

Composition
Active substance:
100 g of the preparation contains: Iodine 1 g
Excipients:
2 g of potassium iodide, glycerin (glycerol) -94 g Purified water 3 g
Description:
Transparent syrupy liquid reddish-brown color with iodine odor.
Product form:
Solution for topical application. 25 g, 30 g, 40 g, 50 g or 100 g of amber glass vials. 1 vial together with instructions for use placed in a pile of cardboard. 1 bottle is placed in a pile of cardboard on which a full text of the instructions for use.
Contraindications
Hypersensitivity, decompensated liver disease and kidney.
Precautions: hyperthyroidism, dermatitis herpetiformis, pregnancy, lactation, children under 12 years.
Dosage
10 mg / g
Indications
Inflammatory diseases of the pharynx and larynx mucous membranes.
Interaction with other drugs
Pharmaceutically not compatible with essential oils, ammonia solutions, a white sediment mercury. The alkalinity or acidity of the medium, the presence of fat, pus, blood impair preservative activity.
Iodine is inactivated with sodium thiosulfate. In case of contact with the drug inside may decrease the effect of drugs that suppress the function of the thyroid gland, and also may vary thyroid function tests.
iodine preparations may exacerbate the irritating effects of some drugs (including aspirin) on the mucosa of the gastrointestinal tract in case of accidental ingestion.
Overdose
Symptoms of irritation of the upper respiratory tract (burn laringo-, bronchospasm); After swallowing – irritation of the mucous membranes of the gastrointestinal tract, hemolysis, hemoglobinuria; lethal dose – about 3 years
Treatment: gastric lavage with 0.5% sodium thiosulfate solution, sodium hydrogencarbonate solution, sodium thiosulfate intravenously 30% – to 300 ml.
pharmachologic effect
Pharmacological group:
Antiseptic.
Pharmacological properties:
The main active substance is molecular iodine antiseptic and irritant effect. It has bactericidal activity against gram-positive and gram-negative flora, as well as pathogenic fungi and yeast; more resistant Staphylococcus aureus, but long-term use of the drug in 80% of cases there is suppression of staphylococcal flora; Pseudomonas aeruginosa is resistant to the drug. When applied to extensive mucosal surfaces iodine has resorptive action: actively influences on metabolism, amplifies dissimilation processes involved in the synthesis of T3 and T4, possesses proteolytic activity.
Part of the potassium iodide improves dissolution of iodine in water and glycerol has a softening effect.
The drug has low toxicity.
Pharmacokinetics:
Resorption of iodine through the skin and mucous membranes of the mouth insignificant. Upon contact with the mucous membranes is 30% converted to iodides. If swallowed, iodine is rapidly absorbed. The absorbed part of a well into the organs and tissues (including the thyroid gland). Write mainly kidneys, to a lesser extent the intestine and sweat. It passes into breast milk.
Conditions of supply of pharmacies
Without recipe.
side effects
Allergic reactions. With prolonged use – the phenomenon of “yodizma”: rhinitis, urticaria, angioneurotic edema, salivation, lacrimation, acne.
special instructions
Iodine passes into breast milk and may potentially have an impact on thyroid function in children who are breastfed.
Sunlight and a temperature above 40 ° C accelerate the degradation of the active iodine.
Storage conditions
At a temperature of 12 to 25 C, protected from light.
Keep out of the reach of children.
Dosing and Administration
Locally. Swab dipped preparation lubricate mucous membrane of the pharynx and larynx.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist