Lioton 1000 1000me gel / 100g g tuba

Description

Composition
Active substance:
100 g of gel contains: heparin sodium – 100 000 IU.
Excipients:
Carbomer 940 – 1.25 g methyl parahydroxybenzoate – 0,12 g propyl parahydroxybenzoate – 0.03 g, ethanol 96% – 30.00 ml, neroli oil – 0.05 g, lavender oil – 0.05 g, trolamine (triethanolamine ) – 0.85 g, purified water – up to 100.00 g
Description:
Colorless or slightly yellowish tinge, almost transparent gel viscous consistency with a pleasant smell.
Product form:
Gel for external use 1000 IU / g.
30, 50 or 100 g in aluminum tubes internally coated with epoxy resin, a screw-cap-puncher (polyethylene / polypropylene).
1 tube together with instructions for use in a cardboard package.
Contraindications
Increased sensitivity to the drug; violation of integrity of the skin at the site of the drug (open wounds, ulcerative necrotic lesions); increased tendency to bleeding, thrombocytopenia; age 18 years (the safety and efficacy of the drug has not been studied).
Indications
Disease of the superficial veins: varicose veins, chronic venous insufficiency and associated complications (thrombophlebitis, periflebit); blunt injuries and soft tissue injuries; subcutaneous hematoma, including hematoma after surgery on veins, phlebectomy; localized infiltrates and edema of soft tissues.
Interaction with other drugs
Not recommended simultaneous application for external use, containing tetracycline, antihistamines or steroidal antiinflammatory agents.
Overdose
Very low systemic absorption of the active ingredient of the drug when applied externally makes practically impossible overdose.
In case of overdose effect of heparin may be neutralized with a solution of protamine sulfate.
pharmachologic effect
Pharmacological group:
Anticoagulant means of direct action for topical application.
Pharmacodynamics:
Sodium Heparin – direct anticoagulant action, refers to a group srednemodekulyarnyh heparins. Prevents thrombus formation, inhibits the activity of hyaluronidase, activates the fibrinolytic properties of blood.
When applied externally has a local antithrombotic, anti-oedematous and anti-inflammatory action, improves blood circulation and activate tissue metabolism, thereby accelerating the processes of resorption hematoma, prevented thrombus formation, tissue edema decreases.
Pharmacokinetics:
When applied topically penetrate small amount of heparin in the systemic circulation, without causing systemic effects without causing any changes of blood coagulation parameters. It does not cross the placental barrier.
Pregnancy and breast-feeding
Use of the drug Lioton® 1000 is not contraindicated during pregnancy and lactation.
Heparin does not cross the placental barrier and into breast milk. Due to the insignificant absorption of heparin when used topically, the drug has no systemic effect on the body. However, before using the product Lioton® 1000 should consult a doctor.
Conditions of supply of pharmacies
Without recipe.
side effects
In some cases there may be a hypersensitivity reaction to the drug manifested by redness and / or pruritus of the skin that are usually tested after cessation of the drug.
special instructions
Should not be applied to the mucous membranes, open wounds and apply the presence suppurative lesions in the intended place of application of the gel.
Prolonged use of the drug Lioton® 1000 extensive areas of the skin and simultaneous application of indirect anticoagulants (warfarin, sinkumar et al.), It is necessary to monitor the prothrombin time and clotting time.
Do not use the drug Lioton® 1000, and deep vein thrombosis.
Effect on ability to drive vehicles and management mechanisms
Lioton® 1000 does not affect the ability to drive vehicles and work requiring high concentration.
Storage conditions
At a temperature not exceeding 25 C. Keep out of reach of children !.
Dosing and Administration
For outdoor applications.
A small amount of gel (3-10 cm), 1-3 times a day applied thinly to the skin and rubbed gently.
When the localized effects of injuries and bruises (hematoma, infiltration, edema of soft tissues) applied until symptoms disappear.
When the initial symptoms of venous insufficiency ( “gravity”, leg pain, swelling venous) applied for 1 – 3 weeks depending on the severity of symptoms.
In chronic venous insufficiency (varicose veins and superficial periphlebitis, superficial thrombophlebitis) to apply for 4 – 6 weeks depending on the severity of symptoms.
The need for further treatment is determined by the doctor.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist