Libeksin muko syrup for children 2% 125ml fl

Description

Composition
Active substance:
100 ml of syrup contains: karbotsistein – 2.000 g;
One spoonful syrup (5 ml) contains 100 mg of carbocisteine, 3.5 g of saccharose and 13 mg of sodium.
Excipients:
Sucrose – 70,000 g methyl parahydroxybenzoate – 0.150 g vanillin – 0.05 g, carmine dye (Ponceau 4R) (cochineal red A (E 124)) – 0.005 g, raspberry flavor – 1.00 mL, cherry flavoring – 0,50 ml sodium hydroxide – to pH = 6,10-6,30, purified water – 100 ml.
Description:
Syrupy red liquid.
Product form:
Syrup for children 20 mg / ml. 125 ml or 200 ml clear glass vial (type III), aluminum closed screw cap with tamper-evident. 1 bottle together with the measuring spoon and instructions for use in a cardboard box.
Contraindications
Hypersensitivity to carbocisteine ​​or other components of the formulation. Gastric ulcer and duodenal ulcer in the acute stage. Chronic glomerulonephritis (exacerbation) cystitis. Pregnancy. Children under 2 years old.
Carefully:
Gastric ulcer and duodenal ulcer in the anamnesis (see. “Special Instructions” section). During breastfeeding. Elderly patients (see. Section “Special Instructions”). Simultaneous treatment with drugs that increase the risk of gastrointestinal bleeding (see. Section “Special Instructions”).
Dosage
20 mg / ml
Indications
Acute and chronic bronchopulmonary diseases and diseases of upper respiratory tract accompanied by the formation of a viscous sputum (tracheitis, bronchitis, tracheobronchitis, bronchial asthma, bronchiectasis) and mucus (inflammation of the middle ear diseases of the nose and paranasal sinuses – rhinitis, otitis media, sinusitis ).
Preparing the patient for bronchoscopy or bronhografii.
Interaction with other drugs
Karbotsistein glucocorticosteroid increases efficiency and antibacterial therapy of inflammatory diseases of the upper and lower respiratory tract. Potentiate the bronchodilator effect of theophylline. Action carbocisteine ​​weaken antitussives and m-anticholinergic medicaments.
Overdose
Symptoms: gastralgia, nausea, diarrhea. Treatment is symptomatic.
pharmachologic effect
Pharmacological group:
Expectorant mucolytic agent.
Pharmacodynamics:
Karbotsistein, being mucolytics, has an effect on the gel-phase endobronchial secretions, glycoproteins breaking disulfide bridges and thus decreasing the viscosity and increasing the elasticity of secretion. Karbotsistein activates sialic transferase – enzyme goblet cells of the bronchial mucosa, normalizes the proportion of acidic and neutral sialomutsinov promotes regeneration of the mucosa, it normalizes its structure, activates the activity of the ciliary epithelium, restores the secretion of immunologically active IgA (specific protection), improves mucociliary clearance.
Pharmacokinetics:
Karbotsistein rapidly absorbed after oral administration, reaching a maximum serum concentration after 2 h. Bioavailability is low (less than 10% of the administered dose) due to possible rapid passage through the liver. The half – about 2 hours. Excreted mainly by the kidneys with metabolites.
Pregnancy and breast-feeding
Pregnancy and lactation: Not recommended (. See section “Contraindications”) due to insufficient clinical data the use of the drug Libeksin Muko® in pregnant women.
Lactation: It is unknown whether karbotsistein excreted in breast milk. During the period of breastfeeding preparation Libeksin Muko® should be used with caution (see. Section ”
Carefully “).
Conditions of supply of pharmacies
Available without prescription.
side effects
Disorders of the gastrointestinal tract Nausea, diarrhea, epigastric pain, gastrointestinal bleeding, vomiting.
Disorders of immune system allergic skin rash and anaphylactic reactions including urticaria, angioedema; itching, rash, fixed drug eruption.
Violations of the skin and subcutaneous tissue
Individual cases bullous dermatitis, such as Stevens-Johnson syndrome and erythema multiforme.
Common disorders
Dizziness, weakness, malaise.
special instructions
Caution should be exercised when using the drug Libeksin Muko® in elderly patients with gastric ulcer and duodenal ulcer in the anamnesis, while receiving drugs that increase the risk of gastrointestinal bleeding (see. Section ”
Carefully “). With the development of gastrointestinal bleeding should stop taking the drug. In applying the drug Libeksin muko® in patients with diabetes or patients complying low-carbohydrate diet, it should be appreciated that one measuring spoon of syrup (5 ml) contains 3.5 g sucrose. Subject patients salt-free or low-salt diet should be appreciated that one measuring spoon of syrup (5 ml) contains 13 mg of sodium. Since Libeksin muko® preparation contains sucrose, its use is not recommended in patients with deficiency of sucrase / isomaltase, fructose intolerance, malabsorption syndrome glucose / galactose
Effects on ability to drive and engage in other potentially hazardous activities
In the period of treatment must be careful when driving and when engaging in other potentially hazardous activities due to the possibility of dizziness and weakness.
Storage conditions
Store at a temperature not higher than 25 C.
Keep out of the reach of children.
Dosing and Administration
Inside.
One spoonful syrup (5 ml) contains 100 mg of carbocisteine.
Children aged 2 to 5 years: one measuring spoon (5 ml) 2 times a day (200 mg per day).
Children over 5 years: one measuring spoon (5 ml) 3 times a day (300 mg per day).
Treatment should not last more than 8 days without consulting a doctor.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist