Lamisil gel dermgel appearance. 1% 15g tuba

Description

Composition
Active substance:
100 g of gel contain: 1 g of terbinafine
Excipients:
benzyl alcohol – 0.5 g, carbomer – 1 g of isopropyl myristate – 10 g, butylated hydroxytoluene – 0.02 g, sorbitan laurate – 1 g Polysorbate 20 – 5 g, sodium hydroxide (in the form of sodium hydroxide solution 30% m / m) – 0.1 g ethanol 96% (vol.) – 10 g water – 71.38 g
Description:
Gel for external application of 1% brilliant white to almost white color.
Product form:
15 g – aluminum tubes (1) – packs cardboard.
Contraindications
Increased sensitivity to terbinafine or to any component of the formulation. breastfeeding; Children up to age 18 years.
Dosage
1 %
Indications
Prevention and treatment of fungal skin infections, including mycosis stop (tinea pedis), jock itch (tinea cruris), fungal infections of the skin smooth body (tinea corporis), caused by dermatophytes, such as Trichophyton (including Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton verrucosum, Trichophyton violaceum), Microsporum canis and Epidermophyton floccosum; pityriasis versicolor (Pityriasis versicolor), caused by Pityrosporum orbiculare (Malassezia furfur).
Interaction with other drugs
Currently, drug interactions terbinafine Dermgel not described
Overdose
No cases of overdose were reported Dermgel terbinafine. Symptoms: random drug ingestion tubes weighing 30 g, containing 300 mg terbinafine base is comparable with taking 1 tablet of terbinafine at a dosage of 250 mg (single dose for adult humans). If you accidentally receive a larger number of terbinafine Dermgel inside you can expect the same side effects as an overdose of terbinafine tablets (headache, nausea, epigastric pain and dizziness). It should also be noted that spray contains ethyl alcohol (9.4% (v / v) Treatment:…, Activated charcoal, symptomatic therapy if necessary.
pharmachologic effect
Pharmacological group:
D01AE15
Pharmacodynamics:
Antifungal agent for external application, with a broad spectrum of antifungal activity. At low concentrations of terbinafine has fungicidal activity against dermatophytes (Trychophyton rubrum, Trychophyton mentagrophytes, Trychophyton verrucosum, Trychophyton violaceum, Trychophyton tonsurans, Microsporum canis, Epidermophyton floccosum), mold (mainly Candida albicans) and certain dimorphic fungi (Pityrosporum orbiculare). Activity against yeast fungi, depending on their type, may be a fungicidal or fungistatic. Terbinafine specifically alters the early stage of the biosynthesis of sterols, occurring in fungi. This leads to a deficiency of ergosterol and to an intracellular accumulation of squalene, which causes death of fungal cells. Action terbinafine accomplished by inhibition of the enzyme squalene epoxidase located on the cell membrane of the fungus. Terbinafine has no effect on cytochrome P450 system in humans and, accordingly, the metabolism of hormones or other drugs.
Pharmacokinetics:
When applied topically absorption of terbinafine is less than 5%. Systemic action slightly expressed.
Pregnancy and breast-feeding
Clinical experience with terbinafine Dermgel for external use in pregnancy is very limited, it is possible to use if the expected benefit to the mother outweighs the potential risk to the fetus. Terbinafine is excreted in breast milk, so it should not be administered to nursing mothers. In experimental studies, the teratogenic properties of terbinafine is not revealed. To date, no reports of any malformations in the application of terbinafine Dermgel.
Conditions of supply of pharmacies
Without recipe
side effects
Determining the frequency of side effects: very common (> 1/10), common (> 1/100 and
special instructions
Terbinafine Dermgel intended for external use only. The drug should not be applied to the face. Avoid exposure of drug in the eye, as it can cause irritation. In case of accidental contact with eyes, immediately rinse with running water, and in the case of persistent phenomena of irritation, seek medical advice. The preparation contains butylhydroxytoluene, which might cause a local application of local allergic reactions (contact dermatitis), as well as irritation of eyes and mucous membranes. It should be borne in mind that the preparation contains 96% ethanol. Caution must be exercised when applying terbinafine Dermgel on damaged skin because alcohol, included in its composition, can cause irritation. Effect on ability to drive and use machines is not affected.
Storage conditions
The drug should be kept out of reach of children at a temperature not higher than 30 ° C.
Dosing and Administration
Outwardly. Before the first use of terbinafine Dermgel should pierce the sealing membrane using the edge on the outer side of the cap. Terbinafine Dermgel used in adults 1 time / day for any of the indications. you must thoroughly clean and dry the affected area before applying the medication. The drug is slightly rubbed into the affected sites as well as the adjacent intact skin. In case of infections involving diaper rash (under the breasts, between the fingers, in the gluteal folds and inguinal) area of ​​application of the gel can be covered with gauze, especially at night. The duration and frequency of application of terbinafine in tinea Dermgel torso, legs – 1 week, 1 time / day; with Tinea pedis – 1 week, 1 time / day; with multi-colored lichen – 1 week, 1 time / day. Reducing the severity of the clinical manifestations usually noted in the first days of treatment. In the case of irregular or premature treatment termination are at risk of recurrent infection. In the event that after a week of treatment shows no sign of improving, you should verify the diagnosis. For elderly patients do not require a correction mode.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist