Kolofort tab for the races. 100 pieces

$9.06

Kolofort tab for the races. 100 pieces

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Description

Composition
Active substance:
Antibodies to human tumor necrosis factor alpha (TNF-alpha) affinity-purified r-0.006 *
Brain-specific proteins Antibodies to the S-100 affinity purified – g 0.006 *
Antibodies to histamine affinity-purified – 0.006 g *
* Applied to the lactose in a mixture of three aqueous-alcoholic active substance dilutions diluted respectively at 10012, 10030, 100200 times.
Excipients:
lactose monohydrate, microcrystalline cellulose, magnesium stearate.
Description:
Ploskotsilindricheskoy tablet form with facet and Valium, from white to almost white color. On the flat side coated with Valium inscription MATERIA MEDICA, on the other flat side applied KOLOFORT inscription.
Product form:
Lozenges. 20 tablets in blisters of PVC film and aluminum foil.
5 the contour of cellular packaging together with instructions for medical application is placed in a pile of cardboard.
Contraindications
Increased individual sensitivity to the drug.
Indications
irritable bowel syndrome; functional disorders of the gastrointestinal tract.
Interaction with other drugs
Incompatibilities with other drugs has not yet been registered.
Overdose
Accidental overdosing possible diarrheal phenomena caused by members of the formulation excipients.
pharmachologic effect
Pharmacological group:
Anti-inflammatory, antispasmodic, anxiolytic agent
Pharmacodynamics:
It is shown experimentally that the components of the drug activity is modified ligand-receptor interaction of endogenous regulators of the corresponding receptors: antibodies to protein S-100 – the serotonin receptors and sigma 1 receptors; antibodies to TNF-alpha – alpha TNF receptor; Antibodies to the histamine – to localized in the gastrointestinal tract (GIT) H4 – histamine receptors.
The combination of three active ingredients allows for a complex effect on the central and peripheral pathogenesis of functional bowel disorders, including abdominal pain.
Antibodies to S-100 protein possess a broad spectrum psychotropic activity, including the anxiolytic and antidepressant, nootropic and antiasthenic effect that is clinically manifested in the removal of internal stress, anxiety, visceral normalization of some functions, including colon activity. Do not have sedation, addiction, withdrawal syndrome. Antibodies to TNF – alpha have a pronounced anti-inflammatory effect, help to normalize the balance of proinflammatory and anti-inflammatory cytokines.
Antibodies to histamine has antispasmodic, anti-inflammatory, anti-edema effect.
The combined use of components in the complex preparation promotes the normalization of neural and humoral regulation of bowel function; reducing visceral hypersensitivity colon receptors stretchability, ensuring recovery of impaired GI motility; relief of bloating and feeling of fullness, reducing the severity of pain. Antispasmodic drug is smooth muscle relaxation and a decrease in gastrointestinal wall tonicity reduce intraluminal pressure, normalization of stool consistency, its frequency and associated symptoms (mild urgency, tenesmus, feelings of incomplete emptying of the intestine, the additional force when the act of defecation et al.).
Pharmacokinetics:
Sensitivity modern physico-chemical methods of analysis (gas-liquid chromatography, high performance liquid chromatography, gas chromatography-mass spectrometry) does not allow to evaluate the content of ultra-low doses of antibodies in biological fluids, organs and tissues, making it impossible to study the pharmacokinetics technically Kolofort preparation.
Conditions of supply of pharmacies
Without recipe
side effects
Possible reactions of individual hypersensitivity to the drug.
special instructions
The preparation includes lactose, in connection with which it is not recommended for patients with congenital galactosemia, malabsorption of glucose or galactose, or with congenital lactase deficiency.
Kolofort does not affect the ability to drive vehicles and other potentially dangerous machinery.
Storage conditions
In the dark place at a temperature not higher than 25 ° C. Keep out of the reach of children.
Dosing and Administration
Inside. At one time – 1 or 2 tablets (kept in the mouth until complete dissolution – not during a meal). Take 2 times a day. The course of treatment – 1 – 3 months; If necessary, treatment can be extended to 6 months and / or repeated after 1-2 months. Against the background of acute diseases may increase the reception frequency up to 4 times a day for 7 to 14 days.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg
Manufacturer

Materia Medica

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