Kloveyt ointment 0.05% 25g tube

$8.72

Kloveyt ointment 0.05% 25g tube

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SKU: 01787172738 Categories: , , Tags: ,

Description

Composition
Active substance:
1 g of cream contains: clobetasol propionate 0.5 mg.
Excipients:
Propylene glycol, sorbitan sesquioleate, white petrolatum 1.0 g
Description:
White, translucent, oily, soft smooth.
Product form:
Ointment for external use 0.05%.
25 g of ointment lithographed lacquered aluminum tubes with an inner surface.
Lithographed tube is placed in a cardboard box with instructions for use.
Contraindications
Rosacea.
Acne vulgaris.
Skin cancer.
Nodular prurigo Gajda.
Perioral dermatitis.
Perianal and genital itching.
Cutaneous manifestations of syphilis, diaper rash.
Bacterial, viral and fungal diseases of the skin (including herpes simplex, varicella, lupus, actinomycosis).
Spread plaque and pustular psoriasis.
Hypersensitivity to the active drug and excipients.
Up to 1 year.
Lactation.
Pregnancy.
Indications
Psoriasis (except and extensive pustular psoriasis plaque).
Eczema (various forms).
Lichen planus.
Discoid lupus erythematosus.
Skin diseases that are resistant to therapy less active corticosteroids for topical use.
Interaction with other drugs
No data.
Overdose
The development of acute overdose unlikely. However, in the case of chronic overdose or misuse of hypercortisolism may develop symptoms that require the gradual withdrawal of the drug events supervision of a physician.
pharmachologic effect
Pharmacological group:
Glucocorticosteroids for local use.
Pharmacodynamics:
Glucocorticosteroids for external application. Warns accumulation of neutrophils boundary, reduces the inflammatory exudation and production of lymphokines inhibits the migration of macrophages, reduces the intensity of infiltration and granulation processes, has a local anti-inflammatory, antipruritic, anti-allergic and anti-exudative effects.
Pharmacokinetics:
The average maximum concentration of clobetasol propionate is reached in plasma after 13 hours after the first application and after 8 hours after repeated application to healthy skin 30 g of clobetasol propionate 0.05% in the form of ointments and 0.63 ng / ml. After 10 hours after application of the second dose (30 g), clobetasol propionate in a cream its mean maximum plasma concentration slightly higher than that of ointments. After 3 hours after a single application of 25 g of 0.05% clobetasol propionate ointment in patients with psoriasis and eczema mean maximum drug concentration in plasma was 2.3 ng / ml and 4.6 ng / ml, respectively.
When applied to extensive areas of skin absorption may (integrity damage or inflammation of the skin enhances absorption) and the manifestation of a systemic effect. Metabolized mainly in the liver, a small part – in the kidney. Excreted by the kidneys.
Pregnancy and breast-feeding
Steroids for topical use should not be used during pregnancy for a long time in large doses.
Security application clobetasol during lactation has not been established.
Conditions of supply of pharmacies
On prescription.
side effects
Burning, itching, steroid acne, dry skin.
With prolonged use: the weakening of the skin barrier function. When applied to large surface may develop systemic side effects (gastritis, ulceration of the gastrointestinal mucosa, increased intraocular pressure, Cushing’s symptoms).
Long term administration of corticosteroids for topical application in large doses or applying them to the vast areas of the skin may be accompanied by systemic absorption and the subsequent development of Cushing’s symptoms. The risk of this complication is elevated in children, especially in the application of occlusive dressings, and the diaper may serve as a bandage.
Provided Kloveyt drug administration to adult patients at a dosage of not more than 50 g per week, suppression of the pituitary and adrenal function has a smooth transient-recovery immediately after completion of treatment.
Prolonged treatment with highly active corticosteroids for topical application in high doses may cause atrophic changes of the skin, in particular its thinning, the appearance of stretch marks (striae), dilation of superficial blood vessels, particularly when applied under occlusive dressings and applied the preparation on skin with wrinkles. May develop skin pigmentation and hypertrichosis. In rare cases of psoriasis glucocorticosteroid treatment for topical use (or cancel) provokes pustular psoriasis.
Rarely Kloveyt drug can cause exacerbation of symptoms.
special instructions
Kloveyt drug, ointment, recommended for skin lesions, accompanied by dryness, hyperkeratosis, thickening.
The drug is recommended for short term use.
Should be avoided glucocorticosteroids for topical administration for a long time, especially in the treatment of young children, as this can happen adrenal suppression. Use of the drug Kloveyt in children requires medical supervision at least once a week.
On the face more often than in other areas of the body may appear atrophic skin changes as a result of prolonged use of local glucocorticosteroids.
Do not apply the drug in the eye area because drug use in peri orbital region can cause the development of glaucoma treatment psoriasis corticosteroids for topical application may be accompanied by the development of relapses, tolerance to the drug, generalized pustular forms of the disease, local or systemic toxic reactions due to a violation of the barrier function of the skin, so it is particularly important close observation of patient.
When joining a secondary infection should be appropriate antibiotic therapy. If any signs of generalized infection should stop the topical application of glucocorticosteroids and conduct appropriate treatment with antibacterial drugs.
Warm moist conditions created upon application of occlusive dressings, contribute to the emergence of a bacterial infection, so be sure to clean the skin before applying a new bandage.
The effect on the ability to drive the vehicle, and maintenance of moving mechanisms.
Does not affect.
Storage conditions
Store at a temperature not higher than 25 ° C. Do not freeze.
Keep out of the reach of children.
Dosing and Administration
Outwardly. The ointment is applied a thin layer to the affected areas of skin 1-2 times a day. The duration of continuous treatment is limited to 3-4 weeks.
In a particularly resistant cases, especially in the presence of hyperkeratosis, ointments Kloveyt anti-inflammatory effect may be enhanced by blending overnight on area of ​​the drug from the bandage of plastic film, which is usually accompanied by a positive effect. If you change the skin occlusive dressings should be cleaned. Subsequently the achieved effect can be maintained without the use of occlusive dressings.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg
Manufacturer

VALEANT

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