Klindatsin cream vaginas. 20g 2% with applicator


Klindatsin cream vaginas. 20g 2% with applicator


SKU: 801884733 Categories: , , Tags: ,


Composition Active ingredient: 1 g of cream contains: clindamycin phosphate in terms of 100% substance – 20 mg ;. Excipients: Sodium benzoate 40 mg, castor oil, 100 mg, 440 mg propylene glycol, emulsifier EM 3398 100 mg Macrogol-1500 300 mg. Description: Cream white to white with yellowish or Valium a color shade. Presence of weak specific smell. Product: vaginal cream 2%. 20 or 40 g of aluminum into a tube. Each tube 20 together with 3 g of applicators and instructions for use, or the tube 40 together with 7 g of applicators and application instructions are placed in a pile of cardboard. Contraindications: Hypersensitivity to clindamycin or lincomycin. Dosage 0.02 Indications Bacterial vaginosis caused by sensitive microorganisms. Interaction with other drugs between clindamycin and erythromycin marked antagonistic interaction. Cross-resistance exists between clindamycin and lincomycin. Overdosing When drug overdose intravaginal application is not installed. The drugs group: Antibiotic – lincosamide. Pharmacological properties: Antibiotic lincosamides group for vaginal use. The mechanism of action of the drug associated with impaired intracellular protein synthesis in a microbial cell at ribosomal 50S subunits. Clindamycin has a broad spectrum of action, bacteriostatic action, at higher concentrations, in respect of some microorganisms – bactericidal. It is active against organisms that cause bacterial vaginosis: Gardnerella vaginalis, Mobiluncus spp., Bacteroides spp., Mycoplasma hominis, Peptostreptococcus spp. To clindamycin is not sensitive Trichomonas vaginalis and Candida albicans. Pharmacokinetics after single intravaginal administration of 100 mg of clindamycin, an average of 4% of the administered dose undergoes systemic absorption. The maximum concentration of clindamycin in the plasma is 20 ng / ml. Pregnancy and lactation No clinical studies on the use of clindamycin for women in I trimester of pregnancy is not carried out, so the use of the drug is possible only if the expected benefit to the mother outweighs risk to the fetus. Application in II and III trimester of pregnancy is possible, since not revealed any adverse effects on the fetus. It is not known whether clindamycin is released from the mother’s milk in intravaginal application, therefore it is necessary to compare the benefits of the drug during breast-feeding and the potential risk to the infant. Conditions of supply of pharmacies by prescription. Side effects may develop allergic reactions, the appearance of irritation at the injection site, cervicitis, vaginitis, vulvovaginal candidiasis. Specific guidance With prolonged use of the drug possible overgrowth insensitive thereto microorganisms, particularly fungi of the genus Candida. Considering the possibility of a minimal systemic absorption of the drug (about 4%), one can not exclude the occurrence of diarrhea during treatment with the drug. In this case, the drug should be discontinued. Not recommended for use concomitantly with other intravaginal means. The efficacy and safety of clindamycin in intravaginal application in children has not been established. In dry storage conditions, protected from light at a temperature not higher than 20 ° C. Keep out of the reach of children. Dosing and dose introduced intravaginally with an applicator. The recommended single dose of 100 mg of clindamycin (one full applicator), preferably at bedtime for 3-7 days. Disposable applicators supplied with the package with Klindatsinom® designed for proper administration of the cream into the vagina. 1. Remove the cap of a tube of cream. Screw the plastic applicator on the threaded neck of the tube. 2. squeezing the tube at the opposite end, gently squeeze out the cream into the applicator. Piston applicator moves independently as required filling volume. The applicator is filled when the piston reaches the stop. 3. Lying on your back, take the applicator horizontally and insert it into the vagina as far as possible, but so as not to cause discomfort. 4. Slowly push the plunger all the way. 5. Carefully remove the applicator from the vagina, and discard it. Info appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

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Weight0.100 kg




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