Ketonal gel 2.5% 50g tube


Ketonal gel 2.5% 50g tube



Active substance:
1 g of gel contains: Ketoprofen – 25.00 mg ;.
Carbomer – 20.00 mg, trolamine (triethanolamine) – 37,00 mg, 96% ethanol – 285,00 mg, lavender oil (Lavender essential oil) – 0.28 mg Water – 632.72 mg.
Homogeneous transparent colorless gel.
Product form:
Gel for topical application, 2.5%
50 g or 100 g of an aluminum tube, sealed at the neck of the membrane tubes, screw-capped plastic cap provided with a cone-shaped device to puncture the membrane. According to one tube together with instructions for use placed in a cardboard box.
Hypersensitivity to ketoprofen or other components of the drug as well as the salicylates, tiaprofenic acid or other NSAIDs, fenofibrate; skin allergy history on sunscreen and perfume; complete or partial combination of asthma, recurrent nasal polyposis and paranasal sinuses and intolerance to acetylsalicylic acid or other NSAIDs (including history); III trimester of pregnancy; children’s age (15 years); violation of integrity of the skin in the area of ​​application of the gel (eczema, acne, dermatitis, weeping, infected wound or open); a history of photosensitivity reactions; exposure to sunlight, including indirect sun rays and UV radiation in the solarium during the entire treatment period and 2 weeks after cessation of treatment.
It should consult a physician before using the gel Ketonal® if you have: dysfunction of liver and / or kidney; erosive and ulcerative lesions of the gastrointestinal tract; blood diseases; bronchial asthma; chronic heart failure; hepatic porphyria (exacerbation).
Symptomatic therapy – reduction of pain and inflammation at the time of use, the progression of the disease is not influenced – under the following conditions: Reactive arthritis (Reiter’s syndrome); osteoarthritis different localization; periarthritis, tendinitis, bursitis, myalgia, neuralgia, sciatica; injuries of the musculoskeletal system (including sports), bruised muscles and ligaments, sprains, torn ligaments and muscle tendons.
Interaction with other drugs
When applied topically in a dosage form of ketoprofen gel possible potentiation of drugs that cause photosensitization.
Patients taking coumarin anticoagulants, it is advisable to carry out regular monitoring of the international normalized ratio (INR).
Ketoprofen, like other NSAIDs, may reduce the excretion of methotrexate and help to increase its toxicity.
Interaction with other medicinal products and the impact on their removal are not significant.
Overdosing is unlikely with topical preparation.
In case of overdose, the skin should be thoroughly rinsed under running water.
In case of contact of the drug may develop into systemic adverse reactions. In this case, symptomatic treatment and supportive therapy as an overdose forms for oral administration.
pharmachologic effect
Pharmacological group:
Nonsteroidal anti-inflammatory drug (NSAID).
Ketoprofen is one of the most effective inhibitors of cyclooxygenase. It also inhibits lipoxygenase activity and bradykinin. Stabilizes lysosomal membranes and prevents the release of enzymes involved in the inflammatory process.
The main properties of ketoprofen are analgesic, anti-inflammatory and anti-edematous action. Ketoprofen has no negative impact on the status of the articular cartilage.
Ketoprofen with a topical application of the gel does not accumulates in the body. Bioavailability gel – approximately 5%. The maximum concentration of ketoprofen in plasma achieved 6 h after drug application. Penetrates into the tissue of the joints, including in synovial fluid, and there reaches therapeutic concentrations. Plasma concentration of the drug is extremely low.
Ketoprofen is metabolized in the liver to form conjugates that are derived mainly kidneys. Metabolism of ketoprofen not dependent on age, presence of severe renal failure or liver cirrhosis. Excretion of ketoprofen kidney is slow.
Pregnancy and breast-feeding
Application in I and II trimesters
Since the safety of ketoprofen in pregnant women has not been evaluated, it should avoid the use of ketoprofen in I and II trimesters of pregnancy.
Application in the III trimester of pregnancy
The drug Ketonal® gel is contraindicated in the III trimester of pregnancy.
During the III trimester of pregnancy, all prostaglandin inhibitors, including ketoprofen, may have toxic effects on the heart, lungs and kidneys of the fetus.
In late pregnancy, may increase bleeding time in mother and child. NSAIDs may delay the onset of labor.
To date, no data on the allocation of ketoprofen into breast milk, therefore the use of the drug Ketonal® gel during breastfeeding is not recommended.
Conditions of supply of pharmacies
Without a prescription.
side effects
According to the World Health Organization (WHO), undesirable effects are classified according to their rate of development as follows: very common (> 1/10), common (by> 1/100 to
special instructions
It is necessary to avoid contact with the gel in the eye, the skin around the eyes, mucous membranes.
When the skin reactions, including those that develop when used together with octocrylene-containing drugs should stop treatment immediately.
Patients suffering from bronchial asthma combined with chronic rhinitis, chronic sinusitis and / or nasal polyposis, or paranasal sinuses, have a higher risk of allergic reactions with the use of aspirin and / or NSAIDs than the rest of the population.
To reduce the risk of photosensitivity is recommended to protect the treated skin with clothing gel on exposure to UV radiation during the treatment period and 2 weeks after cessation of use. Should not exceed the recommended duration of treatment is due to increased risk of developing contact dermatitis and photosensitivity reactions over time.
It is necessary to wash hands thoroughly after each application of the drug.
Information about the negative impact of the gel Ketonal® on ability to drive and engage in other potentially hazardous activities that require concentration and speed of psychomotor reactions, no.
Storage conditions
At a temperature not exceeding 25 C. Keep out of reach of children.
Dosing and Administration
For outdoor applications.
A small amount of gel (3-5 cm) are thin skin inflamed or painful body portion 1-2 times daily and gently rubbed.
The dosage should be adjusted according to the area of ​​the affected area: 5 cm Ketonal® gel correspond to 100 mg of ketoprofen, 10 cm – 200 mg ketoprofen.
If necessary Ketonal® gel can be combined with other medicinal forms Ketonal® formulation (capsules, tablets, rectal suppositories, solution for intramuscular injection).
The maximum dose of ketoprofen is 200 mg / day.
Occlusive dressing is not recommended.
Do not use without consulting a doctor for more than 14 days.
If you forgot to apply the gel, apply it at a time when the next dose, do not double but it should be applied.
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg

Sandoz UTS

There are no reviews yet.

Add your review