Katalin tab for prig.kapel Ch. + 0.75mg solvent 15ml vials.

Description

Composition
Active substance:
1 tablet (1 vial) contains: sodium pirenoxine monohydrate (based on 0.75 mg of pirenoxine) – 0.85 mg.
Excipients:
Aminoethylsulphonic acid (taurine) – 62 mg Boric acid – 12.15 mg.
solvent components: boric acid – 180 mg, sodium borate – 1.2 mg, potassium chloride – 24 mg methyl parahydroxybenzoate – 3 mg propyl parahydroxybenzoate 1.5 mg Purified water – up to 15 ml.
Description:
Pills from orange-red to yellow, complete with a clear colorless solvent. After dissolution, the clear solution from orange-red to yellow.
Product form:
Tablets for the preparation of eye drops 0.75 mg together with the solvent 15 ml. 1 tablet in the blister with aluminum foil and PVC film and transparent solvent 15 ml polypropylene vial amber yellow placed together with instructions for use in a cardboard pack.
Contraindications
Idiosyncrasy. Children age due to insufficient data on safety.
Dosage
0.75 mg
Indications
The initial stages of senile cataracts.
Interaction with other drugs
Drug interactions has not been studied. In the case with other ophthalmic drugs local interval between their application should be at least 5 minutes.
It is not recommended to use simultaneously with eye drops containing metal ions (silver solutions colloid silver, zinc sulfate), since Katalin ® changes color in their presence.
Capabilities and features of application of pregnant women, women during breast-feeding, child
In the absence until now of sufficient studies, the drug is not recommended during pregnancy and breastfeeding.
Overdose
So far, cases of overdose are not logged in.
pharmachologic effect
Pharmacological group:
Cataract means of treatment.
Pharmacological properties:
Katalin ® has an inhibitory effect actions of quinone compounds, the process of fat oxidation and action apdoz reductase and impedes progress of cataract. The data are presented based on theory quinoid, results obtained in guinea pigs.
Pharmacokinetics:
Action quinone substances produced as a result of abnormal metabolism of aromatic amino acids, stimulates the conversion of the water soluble protein insoluble in the lens, whereby the lens material becomes cloudy. By inhibiting the action of substances quinone, pirenoxine prevents the development of cataracts. Based on study data radiolabeled hydrogen when instilled into the eyes of rabbits Katalin preparation ®, pirenoxine concentration in the tear fluid over 2 hours after the instillation is 0.0189 ug eq. / Ml, the maximum concentration after 4 hours after instillation of 0.003 ug eq. / Ml.
Conditions of supply of pharmacies
By prescription.
side effects
Diffuse superficial keratitis, blepharitis, conjunctival hyperemia, itching, burning pain in the eye, contact dermatitis, conjunctivitis, irritation, tearing, eye discharge, discomfort and foreign body in the eye, blurred vision. May cause allergic reactions due to the presence in the formulation parabens. In the event of adverse reactions, use of the drug should be discontinued.
special instructions
Effect of the drug on the ability to drive, the mechanisms
So far, the possibility of influence of the drug on the ability to drive is not established.
Storage conditions
Store at a temperature not higher than 25 C.
Do not freeze.
After dissolution stored protected from light at a temperature not higher than 15 C.
Keep out of the reach of children.
Dosing and Administration
Use only by instillation. Immediately before use, dissolve one tablet in 15 ml of solvent and instilled into the conjunctival sac of 1-2 drops of solution 3-5 times a day. The duration of treatment is determined by the doctor.
Precautions for the use of
When backfilling should not touch the tip of the bottle eyes.
If the solution is instilled immediately after the vial is removed from the cool space, especially in cases where the vial remains a small amount of the solution, the solution can be poured not drip, and jet. This effect is due to expansion of cool air in the bottle under the influence of heat on the bottle hands.
To avoid this effect is necessary to warm the bottle by holding it in your hand for some time prior to instillation.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist