Kagocel tab 12mg 10 pc

Description

Composition
Active substance:
1 tablet contains: Kagocel (in terms of dry matter) – 12 mg.
Excipients:
Potato starch – 10 mg Calcium stearate – 0.65 mg, ludipress (composition: lactose monohydrate – from 91% to 95%, povidone (Kollidon 30) – from 3.0% to 4.0%, crospovidone (Kollidon CL) -from 3.0% to 4.0%) – up to obtain tablets each weighing 100 mg.
Description:
Tablets from white to brownish shade to light brown round biconvex interspersed with brown.
Product form:
Tablets of 12 mg.
Packing 20 tablets.
Contraindications
– Pregnancy and lactation;
– Age up to 3 years;
– Increased sensitivity to the drug;
– lactase deficiency, lactose intolerance, glucose-galactose malabsorption.
Dosage
12 mg
Indications
Kagocel drug used in adults and children from 3 years as a preventive and therapeutic agent for influenza and other acute respiratory viral infections (ARI), and as a remedy for herpes in adults.
Interaction with other drugs
The drug Kagocel well with other antivirals, immunomodulators and antibiotics (additive effect).
Overdose
In case of accidental overdose, it is recommended to appoint a plentiful drink, induce vomiting.
pharmachologic effect
Pharmacological group:
An antiviral agent.
Pharmacodynamics:
The main mechanism of action Kagocel is the ability to induce the production of interferons. Kagocel causes formation in the human body so-called late interferons are a mixture of alpha- and beta-interferons possessing high antiviral activity. Kagocel cause interferon production in virtually all cell populations involved in the antiviral response of the body: T and B lymphocytes, macrophages, granulocytes, fibroblasts, endothelial cells. When one ingestion dose Kagocel titer of interferon in serum reaches a maximum after 48 hours. Interferon response of the organism to the introduction is characterized Kagocel long (up to 4-5 days) interferons circulation in the bloodstream. Dynamics of accumulation in the intestine of interferon when administered Kagocel does not coincide with the dynamics of circulating interferon titers. The serum interferon production reaches high values ​​only 48 hours after receiving Kagocel, while in the intestine maximum production of interferon is noted in only 4 hours.
Kagocel drug, when administered at therapeutic doses, non-toxic, does not accumulate in the body. The drug has no mutagenic and teratogenic properties, not carcinogenic and has no embryotoxic activity.
The highest efficiency in the treatment of drug Kagocel achieved in his appointment no later than the 4th day from the beginning of the acute infection. As a preventive measure the drug can be used in any period of time, including immediately after exposure to an infectious agent.
Pharmacokinetics:
After 24 hours, after administration into the body Kagocel accumulates mainly in the liver, to a lesser extent in the lung, thymus, spleen, kidney, lymph nodes. Low concentrations were in the adipose tissue, heart, muscle, testes, brain, blood plasma. Low content Kagocel in the brain due to the high molecular weight drug, impeding its penetration through the blood-brain barrier. In the preparation of blood plasma it is predominantly in bound form.
With daily repeated administration Kagocel volume of distribution varies widely in all organs. Especially pronounced accumulation of the drug in the spleen and lymph nodes. When administered into the bloodstream misses about 20% of the administered dose. Suck drug circulating in the blood, mainly in the form associated with macromolecules: lipids – 47% protein – 37%. Unrelated of the drug is about 16%.
Excretion: preparation derived from the organism mainly through the intestine: 7 days after administration of the organism displays 88% of the administered dose, including 90% – through the intestine and 10% – kidneys. Breath drug is not detected.
Pregnancy and breast-feeding
Due to the lack of clinical data product is contraindicated to take during pregnancy and lactation.
Conditions of supply of pharmacies
Without recipe.
side effects
May develop allergic reactions.
If any of these instructions side effects are compounded, or if you notice any other side effects not mentioned in the instructions, tell your doctor.
special instructions
To achieve the therapeutic effect of the drug should be started no later than the fourth day from the onset of the disease.
Effects on ability to drive a vehicle engine.
Effect on ability to drive vehicles, has not been studied mechanisms.
Storage conditions
In the dark place at a temperature not higher than 25 C.
Keep out of the reach of children.
Dosing and Administration
Inside, regardless of the meal.
For treatment of influenza and acute respiratory viral infections in adults appoint the first two days – 2 tablets 3 times a day, in the next two days – one tablet 3 times a day. Throughout the course – 18 tablets, course duration – 4 days.
Prevention of influenza and acute respiratory viral infections in adults held 7-day cycles: two days – 2 1 pill once a day, 5 days off, and then repeat the cycle. The duration of prophylactic course – from one week to several months.
For the treatment of herpes in adults prescribed 2 tablets 3 times a day for 5 days. Throughout the course – 30 tablets, course duration – 5 days.
For treatment of influenza and acute respiratory viral infections in children aged 3 to 6 years to designate the first two days – 1 tablet 2 times a day, in the next two days – one tablet 1 time a day. Throughout the course – 6 tablets, course duration – 4 days.
For treatment of influenza and acute respiratory viral infections in children aged 6 years to designate the first two days – 1 tablet 3 times a day, in the next two days – one pill 2 times per day. Throughout the course – 10 tablets, course duration – 4 days.
Prevention of influenza and acute respiratory viral infections in children is carried out 7-day cycles of 3 years: two days – 1 tablet 1 time per day, 5 days off, and then repeat the cycle. The duration of prophylactic course – from one week to several months.
If after treatment there is no improvement or symptoms are aggravated, or there are new symptoms, you should consult with your doctor.
Use according to the drug only indications that the application and in those doses which are specified in the instruction.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist