Itraconazole capsules. 100mg 15 pieces of ozone

Description

Composition
Active substance:
In one capsule: pellets of itraconazole (22%) – 455 mg, relative to the itraconazole – 100 mg.
Excipients:
Capsules Composition: Body: gelatin – 100% kryshechka: indigo dye – 0.0471% titanium dioxide – 1.0% gelatin – up to 100%.
Product form:
Capsules 100 mg of 5, 10 kapsulrazmeschayuts in blisters of PVC film and aluminum foil printed patent. At 5, 10, 15, 20, 30, 50 or 100 capsules in banks of PET for drugs or banks for polymeric drugs with instructions placed in the carton (pack).
Contraindications
• Hypersensitivity to itraconazole or the excipients. • Simultaneous administration of drugs substrates of CYP3A4 isoenzyme. • Simultaneous administration of midazolam (oral) and triazolam. • Simultaneous use of drugs ergot alkaloids such as dihydroergotamine, ergometrine, ergotamine and metilergometrin. • Simultaneous use of eletriptan; nisoldipine. • Congestive heart failure at present or in history. • fructose intolerance, lack of sucrase / isomaltase, glucose-galactose malabsorption. • Children under 3 years old. • Pregnancy and lactation.
Dosage
100 mg
Indications
Fungal infections caused by susceptible pathogens to itraconazole: – Skin and mucous membranes: • vulvovaginal candidiasis; • pityriasis versicolor; • ringworm; • mucosal candidiasis of the oral cavity; • fungal keratitis; – onychomycosis caused by dermatophytes and / or yeast-like fungi; – systemic mycoses: • System aspergillosis and candidiasis, • cryptococcosis (including cryptococcal meningitis): in immunocompromised patients and in all patients with cryptococcosis of the central nervous system itraconazole should be used only in cases where the first-line treatment drugs do not apply or are not effective. • histoplasmosis, blastomycosis •, • sporotrichosis, paracoccidioidomycosis •, • other rarely occurring systemic or tropical mycoses.
pharmachologic effect
Pharmacological group:
Antifungal agent. ATC code J02AC02.
Pharmacological properties:
Itraconazole – synthetic antifungal broad-spectrum triazole derivative. The mechanism of action of itraconazole is to inhibit ergosterol biosynthesis – the major component of the cell membrane of the fungus involved in maintaining the structural integrity of the membrane. Violation of ergosterol synthesis results in a change in membrane permeability and cell lysis that causes the antifungal effect of the drug. Itraconazole is active against infections caused by fungi – dermatophytes (Trichophyton spp, Microsporum spp, Epidermophyton floccosum..); – yeast fungi (. Candida spp, including C. albicans, C. tropicalis, C. pararsilosis, C. krusei, Cryptococcus neoformans, Malassezia spp, Trichosporon spp, Geotrichum spp…); Aspergillus spp .; Histoplasma spp, including H. capsulatum.; Paracoccidioides brasiliensis; Sporothrix schenckii; Fonsecaea spp .; Cladosporium spp .; Blastomyces dermatitidis; Coccidiodes immitis, Pseudallescheria boydii; Penicillium marneffei and many others.
Conditions of supply of pharmacies
Prescription.
Dosing and Administration
Inside, immediately after a meal. The capsules should be swallowed whole. Uncommon: edema syndrome. Very rare: pyrexia.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist