Indomethacin ointment tube 40g 10%

$1.87

Indomethacin ointment tube 40g 10%

5 in stock

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SKU: 01268615861 Categories: , , Tags: ,

Description

Composition
Active substance:
1 g of ointment contains: indomethacin – 10,0,0 mg ;.
Product form:
Ointment for external application 10%.
Contraindications
Hypersensitivity to indomethacin, other NSAIDs, or other components of the preparation (including dimexide), complete or partial combination of asthma, recurrent nasal polyposis and paranasal sinuses and intolerance to acetylsalicylic acid and other non-steroidal anti-inflammatory drugs (including history) , breach the integrity of skin at the site of the intended application, the III trimester pregnancy, infancy (up to 14 years).
Carefully
The simultaneous use of other nonsteroidal anti-inflammatory drugs, hepatic porphyria (exacerbation), erosive ulcerous diseases of the gastrointestinal tract in the acute phase (including gastric ulcer and 12 duodenal ulcer, ulcerative colitis, Crohn’s disease), severe liver and kidney failure, chronic heart failure, asthma, older age, blood coagulation disorders (including hemophilia, prolonged bleeding, bleeding tendency, bleeding iatez); severe renal failure (less than 30 ml / min creatinine clearance), progressive renal disease, severe liver failure or active liver disease, condition after coronary bypass, confirmed hyperkalemia, pregnancy-P 1 trimester, during breastfeeding.
Dosage
10 %
Indications
Articular Syndrome (rheumatoid arthritis, osteoarthritis, ankilozirutoschy spondylitis, gout); traumatic inflammation of soft tissue and musculoskeletal system; neuralgia; myalgia.
The drug is intended for the symptomatic therapy reduce pain and inflammation at the time of use, does not affect the progression of the disease.
Interaction with other drugs
Indomethacin effect is enhanced by its combination with corticosteroids and pyrazolone derivatives. Simultaneous use of the drug with corticosteroids leads to increased ultserogennogo past. Can enhance the effect of drugs cause photosensitization.
Overdose
Overdose symptoms only possible if accidentally swallowed ointments, this may occur when burning in the mouth, salivation, nausea, vomiting. It is necessary to lavage the mouth and stomach; if necessary, appoint symptomatic treatment. Hemodialysis is ineffective.
pharmachologic effect
Pharmacological group:
Nonsteroidal anti-inflammatory drug.
Pharmacological properties:
Anti-inflammatory and analgesic effect due to non-selective inhibition of cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) regulating the synthesis of prostaglandins. It helps to reduce pain, particularly joint pain at rest and during motion, decrease of morning stiffness and swelling of the joints, increase range of motion.
Pharmacokinetics:
Indomethacin penetrates through the skin with repeated application to be accumulated in the tissues, muscles, joints, synovial fluid. When applied topically clinically insignificant amount iidometatsina may enter the systemic circulation, where renal elimination of metabolites and in small amounts in unmodified form, and partially through the gastrointestinal tract.
Conditions of supply of pharmacies
Without recipe.
side effects
Local reactions: eczema, photosensitivity, contact dermatitis, itching and skin flushing, rash at the site of application, dry skin, burning sensation. Systemic reactions: generalized skin rash, allergic reactions (urticaria, angioedema, bronchospastic reactions), anaphylactic reactions. In rare cases – exacerbation of psoriasis. When side reactions should seek medical advice.
special instructions
When the duration of treatment 10 days necessary to check the blood picture (the number of white blood cells and platelets). The ointment should be applied only to undamaged skin, to avoid contact with the eyes or the mucous membranes. In case of contact with eyes, mucous membranes or open wounds observed local irritation – lacrimation, redness, burning, and pain. In this case, the corresponding portion of the body is washed with distilled water or saline. Do not use in the form of occlusive dressings! Do not give to children under 14 years of age due to lack of sufficient clinical experience!
Effect on the ability to drive
For external use of indomethacin is not revealed effects on the ability to drive or operate machinery.
Storage conditions
At a temperature of not higher than 25 C.
Keep out of the reach of children!.
Dosing and Administration
Outwardly. The ointment is rubbed lightly in a thin layer to the skin of painful areas of the body of ointment 2-3 cm (1-1.5 g), 2-3 times a day. The total amount of ointment for adults per day should not exceed 15 cm, extruded from the tube, for children over 14 years – 7,5 cm. The duration of treatment should not exceed 10 days.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg
Manufacturer

Russia

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