Hondroksid tab 250mg 60 pieces

Description

Composition
Active substance:
1 tablet contains sodium chondroitin sulfate – 250.0 mg ;.
Excipients:
Calcium stearate – 4.8 mg Crospovidone – 12.39 mg, povidone K30 – 9,312 mg Microcrystalline cellulose – 96.0 mg magnesium hydroxycarbonate pentahydrate – 107.498 mg.
Description:
Tablets from white to white with yellowish or kremovatam color allowed impregnations, with Valium and chamfered.
Product form:
Tablets of 250 mg. 10 tablets in blisters. 6 the contour of cellular packaging together with instructions for medical use of the formulation was put in a cardboard pack.
Contraindications
Hypersensitivity to the drug, children’s age (efficacy and safety in children has not been established), pregnancy, breastfeeding.
Dosage
250 mg
Indications
Degenerative-dystrophic diseases of the spine and joints treatment and prevention of osteoarthritis, degenerative disc disease of the spine.
Interaction with other drugs
May increase the action of indirect anticoagulants, antiplatelet agents, fibrinolytics.
Overdose
Symptoms: rare – nausea, vomiting, diarrhea, chronic administration at excessively high doses (greater than 3 g / day) are possible hemorrhagic lesions.
Treatment: symptomatic therapy.
pharmachologic effect
Pharmacological group:
Tissue repair stimulant of natural origin.
Pharmacodynamics:
It has hondrostimuliruyuschee, regenerating, anti-inflammatory effect. Hondroksid® involved in the construction of the basic substance of cartilage and bone tissue; It affects the metabolic processes in hyaline and fibrous cartilage, inhibits enzymes that cause cartilage damage. The drug inhibits the processes of destruction of cartilage and stimulates the reparative processes in the articular cartilage.
Hondroksid® stimulates the biosynthesis of proteoglycans, promotes regeneration of articular cartilage surfaces of the bag and of the joints with anti-inflammatory action. Slows bone resorption and reducing calcium loss, accelerates bone regeneration.
Hondroksid® slow the progression of osteoarthritis and degenerative disc disease. In applying Hondroksid® drug reduced pain and improved mobility of the affected joints, the therapeutic effect lasts for a long time after the end of therapy.
With structural similarity to heparin may potentially inhibit the formation of fibrin clots in synovial and subchondral microvasculature.
Pharmacokinetics:
Suction
In single ingestion sredneterapevticheskih dose maximum plasma concentration is reached after 3-4 hours, in the synovial fluid – within 4-5 hours. Bioavailability is 13%.
Distribution
Accumulates mostly in the cartilaginous tissue (maximum concentration in the articular cartilage is reached after 48 hours); synovium is not an obstacle to its penetration into the joint cavity.
breeding
Excreted by the kidneys within 24 hours.
Conditions of supply of pharmacies
Without recipe.
side effects
frequency score seldom – by> = 0.01%
Disorders of the gastrointestinal tract: rarely – nausea, vomiting, diarrhea.
Disorders of immune system: rare – allergic reactions.
special instructions
In a joint application of the drug with indirect anticoagulants, antiplatelet agents, fibrinolytics require more frequent monitoring of blood coagulation parameters.
It does not affect the ability to drive and other mechanisms.
Storage conditions
In dry protected from light at a temperature not higher than 25 ° C.
Keep out of the reach of children.
Dosing and Administration
Inside, and 0.5 g (2 tablets), 2 times a day.
Tablets are taken with a little water.
The recommended duration of the initial course of treatment is 6 months. The therapeutic effect of the drug is maintained for 3-5 months after its cancellation, depending on the location and stage of the disease. If necessary, may repeat courses of treatment, the duration of which is determined individually.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist