Heparin-1000 quinacrine gel 1000me / g 50g tube 1 piece

Description

Composition
Active substance:
100 g of gel contains: heparin sodium on a dry matter – 0.83 g (100,000 I.U.) ;.
Excipients:
Methyl parahydroxybenzoate – 0.15 g, Carbomer 940 – 1.25 g, Trometamol – 0.85 g, 96% ethanol (rectified ethyl alcohol) – 24 g, lavender oil – 0.02 g, oil of orange flowers (neroli oil) – 0.01 g purified water – 100 g
Description:
Clear or almost clear, colorless or slightly yellowish tint gel with specific odor.
Product form:
Gel for external use 1000 IU / g.
30 or 50 g in a tube of aluminum. Each tube together with instructions for use in a stack of cardboard.
Contraindications
Hypersensitivity to any of the components of the drug, the ulcer-necrotic skin lesions in places intended application of the gel, traumatic breach of integrity of the skin, reduced blood clotting, and thrombocytopenia.
Dosage
1000 IU / g
Indications
Thrombophlebitis of superficial veins; localized edema and infiltration of soft tissues; tendon and joint injuries, bruises of soft tissues and joints.
Interaction with other drugs
Do not mix with other agents for external application. Do not appoint locally simultaneously with non-steroidal anti-inflammatory drugs, tetracycline, antihistamines. The combined use of a gel with oral anticoagulants may cause elongation of prothrombin time.
Overdose
Overdosing is unlikely due to the low absorbability of the gel components. Manifested bleeding. Cleared protamine sulfate (chemical antagonist).
pharmachologic effect
Pharmacological group:
Anticoagulant means of direct action for topical application.
Pharmacodynamics:
Direct anticoagulant, anti-inflammatory, antiproliferative, anti-inflammatory and analgesic effects. Decreases platelet aggregation binds antithrombin III, preventing the passage of prothrombin to thrombin. Depresses the activity of thrombin. It reduces the activity of hyaluronidase, increases fibrinolytic properties of blood. Improves microcirculation and activates tissue metabolism, thereby accelerates the resorption of hematomas and blood clots, eventually restores patency of vein is clinically accompanied by a pronounced analgesic and anti-inflammatory action.
Pharmacokinetics:
Minor amounts of heparin absorbed from the skin into the systemic circulation. The maximum concentration of active substance in the blood observed after 8 hours after application. Excretion of heparin occurs mainly via the kidney, half-life 12 hours.
Pregnancy and breast-feeding
The drug is not contraindicated during pregnancy and lactation.
Conditions of supply of pharmacies
Without recipe.
side effects
Skin allergies, skin hyperemia.
special instructions
Not recommended for use in bleeding disorders, as well as on open wounds, mucous membranes and the presence of local purulent processes. Use with extreme caution in increased vascular permeability. Application of the gel is not recommended for deep venous thrombosis.
Storage conditions
At a temperature of 15 to 25 C. Keep out of reach of children.
Dosing and Administration
Outwardly. The gel was applied thinly to the affected area at the rate of 3-5 cm of the gel to the skin portion with a diameter of 3-5 cm and gently rubbed into the skin. Apply 1-3 times a day every day until the disappearance of inflammation, an average of 3 to 7 days. Timing of treatment determined by the doctor.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist