Grammidin spray metered + 0.06mg 0.1mg / dose vials 112doz

Description

Composition
Active substance:
1 dose contains gramicidin C dihydrochloride – 0.0638 mg (in terms of gramicidin S – 0.06 mg), cetylpyridinium chloride – 0.10 mg.
Excipients:
Ethanol 96% -19.00 mg, sucralose – 0.20 mg Glycerol – 33.20 mg Peppermint flavor – 0.82 mg citric acid monohydrate – 0.058 mg of sodium citrate – 0.022 mg of polysorbate 80 – 0.40 mg methyl parahydroxybenzoate (methyl paraben) – 0.184 mg propyl parahydroxybenzoate (propylparaben) – 0.02 mg purified water – up to 0.2 ml.
Description:
Transparent or opalescent colorless or yellowish solution with a characteristic odor of mint.
Product form:
Spray dosed topical 0.06 mg + 0.1 mg / dose.
By 112 dose vials made of glass or aluminum coated with plastic, provided with a pump and with a folding pusher cannula.
1 bottle together with instructions for use in a cardboard pack.
Contraindications
-Increased sensitivity Gramicidin S, cetylpyridinium chloride and other ingredients; -Pregnancy (I term); is the period of lactation; -children up to age 18 years.
Carefully
Pregnancy (P-W term).
Dosage
0.06 mg + 0.1 mg / dose
Indications
Infectious and inflammatory diseases of the oral cavity and throat: pharyngitis, tonsillitis, periodontitis, gingivitis, stomatitis.
Interaction with other drugs
Currently not described cases clinically significant interactions with other drugs.
Overdose
Symptoms: The use of the drug in doses higher than recommended, can cause disorders of the gastrointestinal tract: nausea, vomiting, diarrhea.
Treatment: You should stop using the product and seek medical advice.
pharmachologic effect
Pharmacological group:
+ Antibiotic antiseptic.
Pharmacodynamics:
A combined preparation for the treatment of infectious and inflammatory diseases of the throat and mouth.
The preparation includes an antimicrobial agent gramicidin C and antiseptic – cetylpyridinium chloride. The mechanism of action of gramicidin C is associated with increased permeability of the cytoplasmic membrane of a microbial cell that gives its resistance and causes death. Gramicidin C has antibacterial activity against a broad spectrum of gram-positive and gram-negative microorganisms. Cetylpyridinium chloride relates to antiseptic agents, inhibits the growth and multiplication of pathogens of the mouth and throat infections. The drug has antimicrobial effect, reduces inflammation, softens the unpleasant sensation in the throat, swallowing easier.
Pharmacokinetics:
The preparation of local action. According to preclinical studies Pharmacokinetics Absorption is virtually nonexistent.
Pregnancy and breast-feeding
Before using the product if you are pregnant or suspect that you might be pregnant, or planning to become pregnant, you must consult your doctor. Adequate controlled trials of the drug during pregnancy was conducted. Use of the drug in the I trimester of pregnancy is contraindicated. Use of the drug in II-III trimester of pregnancy is possible if the potential benefit to the mother outweighs the potential risk to the fetus. No data on the penetration of the components of the drug in breast milk. If necessary, use during lactation should stop breastfeeding.
Conditions of supply of pharmacies
Without a prescription.
side effects
Allergic reactions to components of the formulation.
If you have marked side effects listed in the instructions, or they are compounded, or if you notice any other side effects not mentioned in the instructions, tell your doctor.
special instructions
Do not use the drug in the presence of open wounds in the mouth, as cetylpyridinium chloride slows wound healing.
Formulation contains ethanol. The maximum single dose of the drug content of ethanol to 0.08 g of
Effects on ability to drive vehicles, machinery.
The drug does not affect the ability to perform potentially hazardous activities that require special attention and speed of reaction (control of the vehicle and other vehicles, work with moving machinery, manager and operator of the work, etc.).
Storage conditions
The original package at a temperature not higher than 25 ° C.
Keep out of the reach of children.
Dosing and Administration
Locally, by spraying on the mucosa of the mouth and throat. It applies after a meal.
The dosage for adults: 4 injection per application three times a day for 7 days.
Immediately after application of the preparation should refrain from eating and drinks for 1 hour.
If after treatment there is no improvement or symptoms are aggravated, or there are new symptoms, you should consult with your doctor.
Use according to the drug only indications that the application and in those doses which are specified in the instruction.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist