Gepatrombin rektal g suppositories. 10 pieces

$5.64

Gepatrombin rektal g suppositories. 10 pieces

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SKU: 651968596 Categories: , Tags: ,

Description

Composition
Active substance:
Heparin sodium lauromacrogol 600 + + Prednisone
Description:
Suppositories are white, conical shape; on a section of white, homogeneous.
Product form:
Rectal suppositories. 5 suppositories in blisters made of PVC. 2 blisters together with instructions for use placed into cardboard pack.
Contraindications
hypersensitivity to the drug; bacterial, viral, fungal infections of the skin; tuberculosis; syphilis; skin tumors (anorectal area); predisposition to bleeding; response to vaccination; I trimester of pregnancy; Children up to age 12 years.
Indications
external and internal hemorrhoids; thrombophlebitis hemorrhoidal veins anus; fistulas, eczema and pruritus in the anus; anal fissure; preparation for surgery in the anorectal region; in the complex therapy of thrombosed hemorrhoids or operated.
Interaction with other drugs
Interactions with other drugs have been identified. Not recommended simultaneous use with other preparations for rectal administration.
Overdose
Not identified.
pharmachologic effect
Pharmacological group:
Anticoagulant means of direct action for local application + other drugs.
Pharmacodynamics:
Combination drug with anti-thrombotic, anti-inflammatory and venoskleroziruschim action for local use in proctology. Heparin – anticoagulant direct action. When applied externally has a local antithrombotic, protivoekssudativnoe and mild anti-inflammatory effect; promotes regeneration of connective tissue; It prevents the coagulation of blood in the hemorrhoids. Prednisolone – glucocorticosteroid, anti-inflammatory, anti-allergic effect and protivoekssudativnoe, reduces itching, burning sensation, pain in the anorectal region. Lauromacrogol 600okazyvaet mestnoanesteziruyuschee effect and provides hardening of hemorrhoids.
Pharmacokinetics:
heparin
After adsorption of plasma protein binding of 95%. From the tissue is slowly released from the half-release about 1 hr. 50% active substance remains on the skin after administration. The release rate is dependent on the dose. After absorption is metabolized in the liver (hepatic enzyme heparinase partially) and reticuloendothelial system. 20-50% is excreted in the urine in unchanged form and partly as urogeparin having a weak anticoagulant effect. The degree of separation depends on the dose (lower doses have a short half-life in plasma).
prednisolone
Prednisolone after absorption is metabolized in the liver. About 1% is excreted in the urine in unchanged form. Biological T1 / 2 of 18-36 hours, and the T1 / 2 of plasma – 115-212 min.
Pregnancy and breast-feeding
Application in I trimester of pregnancy – contra. In the second and third trimester of pregnancy and lactation – use with caution when the expected benefit to the woman than the potential risk to the fetus and infant.
Conditions of supply of pharmacies
Without recipe
side effects
Systemic reactions: allergic reactions, skin flushing. With prolonged use and / or applied to the large surfaces are possible systemic side effects deceleration regeneration cracks, swelling.
special instructions
Just as in the treatment with all other corticosteroids, care must be taken not to use the drug in large amounts or over long periods.
The drug has no effect on the ability to manage road and potentially dangerous machinery.
Storage conditions
Store at a temperature of from 15 to 25 ° C. Keep out of the reach of children.
Dosing and Administration
Rectal suppositories are administered 1-2 times daily rectal cavity after defecation.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg
Manufacturer

STADA

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