Geparideks gel 50g tuba


Geparideks gel 50g tuba


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Active substance:
100 g of gel contains: heparin sodium on a dry matter – 0.417 g; dexpanthenol – 2.5 g; dimethyl – 15.0 g
Carbomer 940 (Carbopol 980), trometamol (tromethamine), lavender oil, Cremophor RH 40 (makrogolglitserola hydroxystearate, polyoxyl 40 hydrogenated castor oil), isopropanol (isopropyl alcohol), purified water.
Clear or almost clear, colorless or slightly yellowish tint gel with specific odor. Presence of opalescence.
Product form:
Tube 30 g, 50 g or 100 g
Increased sensitivity to the drug, bronchial asthma, severe kidney and / or liver failure expressed human cardiovascular system, pregnancy, lactation, infancy (up to 5 years), the open wound at the site of application.
Swelling, bruising and inflammation of soft tissues, muscles, tendons, tendon sheaths;
Contusions, bruises;
Joint injuries from sprained ligaments and tendons;
shoulder epicondylitis ( “tennis elbow”), tendonitis (tendon inflammation), tenosynovitis (inflammation of the tendon sheath), bursitis (inflammation of the lining of the joint bags);
Periarthritis of shoulder joint;
Acute neuralgia.
Interaction with other drugs
Topical administration of other drugs together with the drug enhances their permeability through the skin.
With simultaneous application Geparideks preparation and medicaments containing sulindac (NSAID), may develop severe toxic reactions (peripheral neuropathy).
Data on overdose of the drug available.
In the case of drug overdose, immediately seek medical attention.
pharmachologic effect
Pharmacological group:
Anticoagulant means of direct action for local application + other drugs. Sodium heparin in combination with other drugs.
The action of the drug due to its constituent active substances: sodium heparin, dexpanthenol, dimethylsulfoxide. Dimethylsulfoxide has anti-inflammatory and anti-edematous action due to inactivation of hydroxyl radicals and improving metabolic processes in inflammation. It provides local analgesic effect by reducing the speed of the nociceptive (pain) pulses in peripheral neurons. Dimethylsulfoxide penetrates through biological membranes (from 50% or more), including the skin, promoting a deeper penetration in the tissue of other formulation ingredients.
Heparin – direct anticoagulant, anti-inflammatory action that promotes regeneration of connective tissue due to inhibition of hyaluronidase activity prevents thrombosis, activates the fibrinolytic properties of blood, improve local blood flow.
Dexpanthenol has anti dermatoprotektornoe action. Improving metabolism, promoting regeneration of damaged tissues.
Physiological concentrations of dimethyl sulfoxide (DMSO) in normal plasma is 40 ng / ml. After 6 hours after application of the preparation the maximum concentration in plasma is 120 ng / ml and maintained until 12 hours after application. 12-25% DMSO absorbed is excreted within the first 24 hours and 37-48% output for 7 days in an unmodified form through the kidneys or in the form of a metabolite (dimethyl sulfone). 3.5-6% of DMSO is output through the lungs in the form of dimethyl sulfide after 6-12 hours after applying the drug.
DMSO half life is 11-14 hours.
Heparin when used topically absorbed slightly.
Dexpanthenol when applied topically after absorption is transformed into pantothenic acid that is part of coenzyme A, which plays an important role in the processes of acetylation and oxidation.
Pregnancy and breast-feeding
Due to the fact that the experience of the application of DMSO in pregnant women to date is insufficient to use the drug during pregnancy is contraindicated.
Dimethyl sulfoxide passes into breast milk, so during the use of the drug should stop breastfeeding.
Conditions of supply of pharmacies
Without recipe.
side effects
Possible local skin reactions (redness, itching and burning sensation at the site of gel), which usually disappear gradually in the treatment process.
Sometimes it may cause an allergic skin reaction. In rare cases, may cause allergic reactions of immediate type (urticaria, angioneurotic edema).
In rare cases during use of the drug in some patients may appear the smell of garlic breath. The smell is caused by dimethyl sulfide, dimethyl sulfoxide is a product of metabolism.
You can change the taste, disappears after a few minutes after applying the gel.
It is extremely rare when applying the drug on extensive areas of the body may cause nausea, diarrhea, shortness of breath, headache, chills.
In case of adverse reactions in the use of the drug is recommended to consult a doctor.
special instructions
Before use, the gel should be thoroughly cleaned area of ​​skin from other drugs and contaminants. Bandaging is possible only after greater penetration of the gel into the skin and evaporation contained in its composition of an alcohol (a few minutes).
Geparideks can not be applied to mucous membranes of the eyes, nose, mouth, open wounds or damaged skin (due to irradiation of strong sunburn, post-surgical scars).
At the time of treatment may be exacerbated skin sensitivity, so the period of its application should be limited to the intense sun bath and solarium. In case of skin reaction, treatment should be discontinued.
Due to the high absorption of dimethylsulfoxide Geparideks not be used in combination with other ointments and gels.
With self-application of the drug should not exceed the recommended maximum dose and time of application of the drug. In the absence of reduction or weighting of symptoms it is recommended to consult a doctor.
Effects on ability to drive a vehicle engine.
The drug does not affect the ability to drive and engage in other potentially hazardous activities that require high concentration and psychomotor speed reactions.
Storage conditions
Store at a temperature not higher than 25 C. Keep out of reach of children.
Dosing and Administration
The drug is applied in a thin layer on the skin surface over the area of ​​soft tissue, joints or tendons (edema, hematoma, inflammation, trauma), and uniformly distribute light rubbing movements.
The procedure is repeated 2-4 times a day for 7-10 days or until the disappearance of such symptoms as pain, swelling, edema, inflammation.
If within 10 days of treatment does not occur a clear improvement, seek medical advice.
Geparideks can be applied by iontophoresis. It must be remembered that the treatment of electric shock can cause local skin irritation reactions. Therefore, you must carefully follow the instructions by the manufacturer, to the use of the drug is not strengthened these local reactions.
Geparideks can be used as ultrasound contact gel during therapy (phonophoresis). The active ingredients of the gel (dimethylsulfoxide and heparin) complement the therapeutic action of ultrasonic waves.
Do not use the drug for more than 8 days without consulting a doctor.
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg


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