Generolon spray appearance. 5% 60ml vial 3 pcs

$45.29

Generolon spray appearance. 5% 60ml vial 3 pcs

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Description

Composition
Active substance:
1 ml of solution contains: minoxidil – 20.00 mg or 50.00 mg ;.
Excipients:
Ethanol (96%) – 571,00 / 243,00 mg, propylene – 104,00 / 520,00 mg, Water – up to 1 ml.
Description:
The colorless or slightly colored yellowish color, transparent aqueous-alcoholic solution of the alcohol smell.
Product form:
Spray for external use 2% and 5%. 60 ml of a solution in a plastic bottle of white color. The vial is closed with a plastic lid screw in white; complete with a plastic metering pump and a nozzle for spraying in a protective sachet. 1 vial together with instructions for use, a plastic metering pump and a nozzle for spraying the protective bag is placed in a cardboard box.
Contraindications
Hypersensitivity to minoxidil or other components of the formulation; age under 18 years; violation of the integrity of the skin, dermatitis of the scalp.
Carefully:
Old age – 65 years.
Dosage
5 %
Indications
Treatment of androgenetic alopecia (hair restoration) and the stabilization process of hair loss in men and women.
Interaction with other drugs
There is a theoretical possibility (there is no clinical evidence) enhance orthostatic hypotension in patients cal. receiving concomitant treatment of peripheral vasodilators. We can not exclude a very small increase in the content of minoxidil in the blood of patients suffering from hypertension and taking minoxidil inside in case of simultaneous use Generolon® drug, although the corresponding clinical studies have not been conducted. Established that minoxidil for topical application may interact with some drugs for external application. Simultaneous use of the minoxidil solution for external application and a cream containing betamethasone (0.05%) leads to a reduction of systemic absorption of minoxidil. Simultaneous use of a cream containing tretinoin (0.05%). It is resulting in increased absorption of minoxidil. Simultaneous application of minoxidil to the skin and formulations for external application such as dithranol and tretinoin, which cause changes in the protective functions of the skin, can lead to increased absorption of minoxidil.
Overdose
Accidental ingestion of the drug & Generolon may cause systemic side effects due to vasodilating properties minoxidil (5 ml of a 2% solution contains 100 mg minoxidil – the maximum recommended dose for adults when administered in the treatment of hypertension, 5 ml of a 5% solution comprises 250 mg minoxidil, i.e. the dose of 2.5 times the maximum recommended daily dose for an adult when taken orally in the treatment of arterial hypertension). 11riznaki overdose: fluid retention, decreased blood pressure, tachycardia. Treatment: to eliminate fluid retention if necessary can be assigned diuretics; for the treatment of tachycardia – beta adren of locators. For treatment ginotenzii enter intravenously 0.9% sodium chloride solution. You should not assign simiatomimeticheskie means, for example. norepinsfrin and epinsfrin having over a cardio activity.
pharmachologic effect
Pharmacological group:
A treatment for alopecia.
Pharmacodynamics:
When applied topically, minoxidil stimulates hair growth in patients with androgenetic alopecia (hair thinning, hair loss). Improves microcirculation and stimulates the passage of the hair cells in the active growing phase changes the effects of androgens on hair follicles. Reduces the formation of 5-alpha-degidrosterona (perhaps indirectly), which plays a significant role in the formation of hair loss. The best effect is rendered with slight disease duration (less than 10 years), the young age of patients, bald spot in the crown of no more than 10 cm, there is at the center of more than 100 bald vellus and terminal hair. Manifestation of signs of hair growth observed after 4 months or more of the drug. The beginning and the severity of the effect may vary in different patients. 5% solution of the drug stimulates hair growth more than a 2% solution, which was noted to increase vellus hair growth. After discontinuation of the drug Generolop to new hair growth stops, and within 3-4 months may restore the original appearance. The exact mechanism of action Generalov® drug in the treatment of androgenic alopecia unknown. Minoxidil is ineffective in case of alopecia caused by the medication, malnutrition (deficiency of iron (Fe), Vitamin A), resulting in hair styling “tight” hairstyles.
Pharmacokinetics:
When applied topically minoxidil is poorly absorbed through the normal intact skin in an average of 1.5% (0.3 – 4.5%) of the total deposited dose enters the systemic circulation. Effect of skin diseases accompanying the absorption of minoxidil is unknown. After termination of the drug about 95% of minoxidil that has entered the systemic circulation, it is output for 4 days. Metabolic biotransformation profile after topical application of minoxidil preparation Generolon® hitherto not completely understood.
Minoxidil is not bound to plasma proteins and excreted by the kidneys by glomerular filtration. Minoxidil does not penetrate the blood-brain barrier. Ekskrstiruetsya predominantly in the urine. Minoxidil and its metabolites are excreted by hemodialysis.
Pregnancy and breast-feeding
You should not use the drug during pregnancy and breastfeeding.
Conditions of supply of pharmacies
Without recipe.
side effects
Local side effects:
The most common side effect is dermatitis of the scalp. Less frequent are more severe cases of dermatitis manifesting as redness, desquamation and inflammation. In rare cases, there is itching scalp, allergic contact dermatitis, folliculitis, hypertrichosis (unwanted hair growth on the body, including facial hair growth in women), seborrhea.
The use of minoxidil can cause hair loss gain rest of the hair growth phase in the transition from the phase with the old hair falls out and in their place new ones grow. This temporary phenomenon usually observed after 2-6 weeks after initiation of treatment and gradually over the next two weeks, is stopped (the first signs of action of minoxidil).
Systemic side effects (if accidentally swallowed drug):
Dermatological diseases: nespstsificheskis allergic reactions (rash, urticaria), swelling of the face.
Respiratory system: dyspnea, allergic rhinitis.
Nervous system: headache, dizziness, vertigo, neuritis.
Cardiovascular system: chest pain, blood pressure fluctuations, increased heart rate, changes in heart rate, swelling.
special instructions
Do not apply the drug to other areas of the body.
Preparation Generolon® applied on a dry scalp after bathing or should wait about 4 hours after drug application before bathing. Do not let your head get wet sooner than 4 hours after applying the product.
Wash your hair when applying Generolon® drug is recommended in the usual way. During the period of preparation Generolon® can use hairspray and other hair care products. Before applying the tools for hair care, you must first apply the drug Generolon® and wait until the treated area of ​​skin is completely dry. There is no evidence that hair coloring, perm execution or use of softeners for the hair can reduce the effectiveness of the drug. However, to prevent possible irritation of the scalp, make sure that the drug has been completely washed away from the hair and scalp before using these chemicals.
Before starting treatment with Generolon® patients must undergo a general examination, including the collection and study of medical history. The physician should make sure that the skin of the scalp is healthy scalp.
When systemic side effects or severe skin reactions patients should stop the drug and seek medical advice.
The composition of the drug Generolon® include ethyl alcohol, which can cause irritation and eye irritation. In case of contact of the drug with sensitive surfaces (eye, irritated skin, mucous membranes) must be flushed with plenty of cold water.
Avoid inhalation drug when dispersed.
After treatment, wash your hands.
Storage conditions
At temperatures above 25 ° C. Keep out of the reach of children!.
Dosing and Administration
Outwardly.
Regardless of the size of the treated area must be applied 1 ml of a solution using the dispenser (7 taps), 2 times a day to the affected areas of the scalp, since the problem area center. After the application it is necessary to wash your hands. The total daily dose should not exceed 2 mg (dose not depend on the size of the affected area). Patients who by using 2% solution is not satisfactory hair growth is observed and the patients for whom it is desirable faster hair growth, it is possible to use a 5% solution.
For men Generolon® drug is most effective for hair loss on the top, for women – for hair loss in middle parting.
Generolon® drug is applied on a dry scalp. The solution does not require rinsing.
The appearance of the first signs of hair growth stimulation possibly after application of the preparation two times a day for 4 months or more. The beginning and the degree of hair growth and hair quality may vary in different patients.
According to anecdotal reports during the 3-4 months following cessation of treatment can be expected to restore the original appearance. The duration of treatment on average – about 1 year.
Preparation for use: Remove the screw cap and fix the metering pump. On top of the pump tube strengthened elongated nozzle for spraying. Press the spray nozzle 3-4 times to ensure that the pump was filled with a solution, then the product can be used.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg
Manufacturer

Belupo

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