Finalgon ointment for naruzhn.prim th 20g tube

Description

Composition
Active substance:
1 g of ointment contains: nonivamide (vanillilamid nonylic acid) (P5VA) 4 mg, nikoboksil (butoxyethyl ester of nicotinic acid) (NSBE) 25 mg.
Excipients:
Diisopropyl adipate (Krodamol) 120 mg; colloidal silicon dioxide 20 mg; Vaseline (paraffin, white soft) 822 mg sorbic acid 2 mg, citronella oil 2 mg 5 mg Purified water.
Description:
Almost colorless or slightly brownish, transparent or translucent, homogeneous homogeneous ointment.
Product form:
Ointment for external use. 20 g or 50 g of aluminum into a tube closed with a cap of plastic material for the punch membrane. Each tube with the applicator, and instructions for use are placed in a pile of cardboard.
Contraindications
Hypersensitivity to nikoboksilu, adjuvants or nonivamide preparation. Do not apply ointment on the sensitive skin of open wounds, inflamed skin, areas of the skin with increased permeability: the neck, abdomen, inner thighs. Children up to age 18 (due to insufficient data pas efficacy and safety for this group of patients).
Indications
Arthritis, rheumatic pain in joints and muscles, sports injuries, bruises and damaged ligaments, muscle pain caused by excessive physical exertion, lumbago, neuritis, sciatica, bursitis, tenosynovitis, acute nonspecific pain in the lower back. For preliminary “warm-up” the muscles before exercise, sports competitions. In the combined vasodilator therapy in disorders of the peripheral circulation.
Interaction with other drugs
Interactions with other drugs used topically or systemically, are not revealed.
Overdose
Symptoms: effect of skin hyperemia and severity of dose-related side effects can be compounded after the application of an excessive amount finalgon ointment. Using excessive amounts of the drug could cause vesicle or pustule at the site of an ointment. Drug overdose can cause systemic reactions (redness upper body, fever, “flushing” of blood, painful congestion, decrease in blood pressure), because nicotinic acid esters possess good transdermal absorption.
Treatment: when using an excess amount of drug effect can be reduced if the ointment removed from the skin surface with vegetable oil or cosmetic cream for greasy basis with eye mucosa (for accidental ingestion) – via medical vaseline. If necessary, it should be carried out symptomatic treatment.
pharmachologic effect
Pharmacological properties:
nonivamide
It is a synthetic analog of capsaicin and has analgesic properties, which are manifested in the gradual penetration of the substance into peripheral nociceptive
C-fibers and A-delta nerve fibers from the second deposition of the drug on the skin. Nonivamide exerts vasodilatory effect which is accompanied by intense prolonged sensation of heat, due to the stimulation of afferent nerve endings in the skin.
Nikoboksil
It is a derivative of nicotinic acid having vasodilating properties, with the participation of prostaglandins E2 and I2. Hyperemic effect nikoboksila (butoxyethyl ester of nicotinic acid) develops faster and has a greater intensity than hyperemic effect nonivamide.
The combined action
Nonivamide and nikoboksil possess complementary vasodilating properties, cause skin flushing, increase the rate of enzymatic reactions, activate metabolism.
The appearance of redness and skin temperature increase within a few minutes after application show a rapid penetration of the active ingredients of the drug into the skin.
Action finalgon manifested locally.
Effect of the drug develops within a few minutes. a maximum effect occurs within 20-30 minutes. The analgesic effect of the combination of 0.4% and 2.5% nonivamide nikoboksila been demonstrated in the study of efficacy in patients with acute nonspecific pain in the lower back found that in patients treated with the drug finalgon (2 cm ointment per application and apply medication to 3 once a day for 4 days), clinically significant decrease in the intensity of pain in the lower back within 4 hours after the first application; on the last day of treatment is determined individually, Taxco clinically significant reduction in pain. In a clinical study found that the reduction of pain began within 1-2 hours.
Pregnancy and breast-feeding
Finalgon special studies of the drug during pregnancy and breastfeeding period is not carried out. Do not use the drug during pregnancy and breastfeeding. Studies of the effect of the drug on fertility have been conducted.
Conditions of supply of pharmacies
Without recipe.
side effects
In the course of clinical studies and long experience with the drug have been identified following side effects:
Immune system: anaphylactic reactions, hypersensitivity. From the nervous system: paresthesia, burning sensation
On the part of the respiratory system: cough, shortness of breath.
Skin and subcutaneous tissue disorders: vesicle or pustule the site of application, erythema, local skin reactions (e.g., contact dermatitis), itching, rash, facial swelling, urticaria, heat sensation at the site of application.
special instructions
The drug causes skin flushing, whereby there redness, the feeling of warmth, itching and burning at the application site. These symptoms may be more pronounced when applying an excess amount of the drug or in case of intensive rubbing on the skin surface. Using excessive amounts of the drug or vigorous rubbing over the skin surface may lead to vesicle or pustule at the site of an ointment. After using finalgon drug should immediately wash your hands with soap and water. Care should be taken to avoid accidental contact with the drug on other areas of the skin or contact with the drug on another person. Avoid accidental contact with the drug on the face, eyes, nose or mouth as it may cause a temporary swelling of the face, facial pain, inflammation of the conjunctiva, eye redness, a burning sensation in the eyes, blurred vision, discomfort in the mouth, and stomatitis. Before or after application to the skin should not take a hot bath or shower. Perspiration or heat application to the site of application of the drug can cause reddening of the skin and an intense feeling of warmth even several hours after application finalgon. In the composition preparation contains sorbic acid, which may cause local skin irritation (e.g., contact dermatitis).
Effects on ability to drive and use machines
Special clinical studies of the effect of the drug on the ability to drive and not carried out mechanisms. However, during use of the drug caution should be exercised when driving and operating machinery.
Storage conditions
At temperatures above 25 C, the reach of children.
Dosing and Administration
Treatment should start with the application of small amounts of drug on a small area of ​​skin to assess individual responses. Individual response to the drug can vary greatly: some people will be enough to apply a small amount of ointment, in order to cause the desired effect of warming while others razoprevayuschy effect will be negligible or absent. Root application necessary with the smallest dose. To do this using the provided applicator column preparation, not larger than 0.5 cm is applied to the appropriate size of the skin area with palm with light rubbing movements. To enhance the therapeutic effect of the skin area to which the formulation is applied can be covered by a woolen cloth. With repeated use of the reaction is not the ointment can be reduced, which requires an increase in the dose that is selected individually. The maximum recommended dose of the drug coating constitutes no more than 1 cm in size with palm area (about 10 x 20 ohm cm). If necessary, use the ointment 3 times a day. Day preheating muscles before exercise, sports competitions is recommended to rub about 30 minutes before they begin. In the absence of the desired effect within 10 days refer to the specialist. After applying the product on the skin should be thoroughly wash your hands with soap and water.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist