Fastum gel appearance. 2.5% 50g tube

Description

Composition
Active substance:
100 g of gel contains: Ketoprofen – 2.50 g
Excipients:
Carbomer 940 – 1.50 g, ethanol 96% – 40.00 ml, neroli oil – 0.05 g, lavender oil * – 0.05 g, trolamine (triethanolamine) – 2.80 g Purified water – up to 100, ’00 * lavender oil is a hybrid ( “Lavandin”).
Description:
Colorless, almost transparent gel is a viscous consistency, with a pleasant smell.
Product form:
Gel for topical application, 2.5%.
30 g, 50 g or 100 g in tubes made of soft aluminum coated with epoxy-phenol lacquered inside with a screw cap-puncher (polyethylene / polypropylene) or 100 g in a polypropylene container with a dosing device (dispenser).
According to one tube 1 or dispenser together with instructions for use in a cardboard box.
Contraindications
Individual hypersensitivity to ketoprofen or other ingredients, acetylsalicylic acid or other NSAIDs (indicating a history of bronchospasm, urticaria and rhinitis caused by the intake of acetylsalicylic acid), and fenofibrate; increased skin sensitivity to sunlight exposure (photosensitivity) history; cutaneous history of allergy to ketoprofen, tiaprofenic acid, fenofibrate, sunscreens and perfume; sun exposure on the treated areas, including a sun deck during the course of the drug, and 2 weeks after. oozing dermatitis, eczema, infected abrasions, wounds (in the place of application of the gel); Children up to age 12 years (effectiveness and safety have been studied); pregnancy and lactation.
Precautions: severe renal impairment, advanced age.
Dosage
2.5%
Indications
The pain of traumatic origin (bruises, sprains and muscle); tension and stiffness of the neck muscles; lumbago (pain in the lumbosacral spine); muscle and bone – joint pain rheumatic proiskhodzheniya (eg osteoarthritis).
Interaction with other drugs
When applied topically as a gel ketoprofen possible potentiation of drugs that cause photosensitization. Other interactions have not been established. However, patients taking coumarin anticoagulants are recommended regular monitoring of the international normalized ratio (INR).
Overdose
Very low systemic absorption of the active components of the preparation for external application makes it virtually impossible to overdose.
In case of accidental ingestion of large amounts of the drug may be a manifestation of systemic side effects. Treatment should be symptomatic.
pharmachologic effect
Pharmacological group:
Nonsteroidal anti-inflammatory drugs (NSAIDs) for local application.
Pharmacodynamics:
The mechanism of action of the drug associated with inhibition of prostaglandin synthesis. Ketoprofen has analgesic and protivovocpalitelnoe action. Ketoprofen, penetrate through the skin, reaching the hearth of inflammation, thus providing the possibility of local treatment of lesions (joints, tendons, ligaments and muscles), accompanied by pain syndrome.
Pharmacokinetics:
When applied topically, penetrates the focus of inflammation through the skin absorption of ketoprofen inflammatory focus is extremely slow (gel bioavailability – about 5%). After application of a dose of 50-150 mg of ketoprofen concentration in blood plasma after 5-8 hours of 0.08-0.15 g / ml. Virtually accumulates in the body. The half-life of 1-3 hours. Communication with the plasma proteins 60 – 90%. Excreted mainly via the kidneys as glucuronide.
Pregnancy and breast-feeding
Fastu® The drug is contraindicated in pregnancy and during breastfeeding.
Conditions of supply of pharmacies
Without a prescription.
side effects
Possible side effects are listed in descending frequency of occurrence: very often (> 10%), frequent (> 1%> 10%), rare (> 0.1%> 1%), rare (> 0.01%> 0.1%), very rarely (> 0.01%).
For the skin:
Uncommon: erythema, itching, eczema;
Rare: photosensitivity, bullous dermatitis, urticaria;
Very rarely, contact dermatitis, angioedema.
On the part of the gastrointestinal tract:
Very rare: peptic ulcers, bleeding, diarrhea
Immune system:
Very rare: anaphylactic reactions, hypersensitivity reactions.
From the urinary system:
Very rare: aggravation of current renal failure.
special instructions
Do not apply to damaged (in Vol. H. The open wounds) and inflammation of the skin!
Avoid eye (conjunctiva irritation hazard).
It is recommended to wash hands thoroughly after using the drug.
Do not use in a hermetic casts. Do not use in combination with a tight dress.
Long-term use of topical agents can lead to increased sensitivity or local irritation. To avoid any manifestations of hypersensitivity or photosensitization, avoid exposure to sunlight (in t. H. The solarium) during treatment and for two weeks after the drug is recommended to cover the areas to be treated clothes.
Patients with severe renal, cardiac or hepatic insufficiency should be careful when applying Fastum® preparation.
It should stop using the product in the event of any skin reatskii including while soltsezaschitnyh applied to the skin or other cosmetics containing organic sunscreen octocrylene.
Using the drug in large quantities may, in very rare cases, the development of systemic side effects (hypersensitivity, asthma, disorders of the gastrointestinal tract, worsening course of renal failure).
The risk of systemic effects poboychnyh increases depending on the amount of gel applied, the area of ​​the treated skin area, skin condition, the treatment duration.
Avoid exposure to sunlight or UV-rays including a solarium at processed portions during treatment and for two weeks after treatment.
Effect on ability to drive vehicles and management mechanisms
Fastum® drug does not affect the ability to drive vehicles and work requires high concentration of attention.
Storage conditions
Store at a temperature not higher than 30 C.
Drug store out of reach of children !.
Dosing and Administration
For outdoor applications.
When using tubes: gel strip 5-10 cm in length coated with a thin layer to the affected area of ​​the skin or inflammatory focus 1-2 times daily and gently rubbed.
When using the container with the dispenser (dispenser): double-press on the dome of the dispenser or on the base until the gel. It is recommended to keep the container in a horizontal position. Gel thin layer applied to the affected area of ​​the skin or inflammatory focus 1-2 times daily and gently rubbed.
Quantity of gel applied depends on the area to be treated.
Perhaps the use of the drug Fastum® in conjunction with physical therapy (phonophoresis and iontophoresis).
The course of treatment 10 days.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist