Ersefuril caps. 200mg 28 pieces

Description

Composition
Active substance:
1 capsule contains: nifuroxazide – 200 mg ;.
Excipients:
Corn Starch – 88.0 mg, sucrose – 72.0 mg Magnesium stearate – 1.8 mg.
Capsule Shell: Gelatin – 100%, a titanium dioxide (E171) – 2.0% ferric oxide, yellow dye (E172) – 0.6286%; cap: gelatin – 100%, a titanium dioxide (E171) – 2.0% ferric oxide, yellow dye (E172) – 0.6286%.
Description:
Hard gelatin capsules № 1 consisting of cor- Pusa yellow and yellow caps. Contents of capsules – powder yellow.
Product form:
Capsules 200 mg. 14 capsules in blisters made of PVC / aluminum foil. 1 or 2 blisters together with instructions for use in a cardboard box.
Contraindications
Hypersensitivity to nitrofuran derivatives or any of the excipients of the drug.
Children up to age 6 years.
Pregnancy.
Fructose intolerance syndrome glucose-galactose malabsorption or sucrase and isomaltase deficiency (due to the presence of sucrose in the composition of the drug).
Dosage
200 mg
Indications
Acute bacterial diarrhea flowing without deterioration in general condition, fever, intoxication (in addition to adequate severity of diarrhea by rehydration and electrolyte fluid receiving inwards or, if appropriate, their intravenous administration).
Interaction with other drugs
No data.
Overdose
No data.
pharmachologic effect
Pharmacological group:
Antimicrobials nitrofuran.
Pharmacodynamics:
Like other nitrofurans, nifuroxazide blocks some redox enzyme reactions in microbial cells. When used in therapeutic doses it has a bacteriostatic action, in high doses – bactericidal. Highly active against Campylobacter jejuni, Escherichia coli, Salmonella spp, Shigella spp; Clostridium perfringens, Vibrio cholerae, pathogenic Vibrions and Vibrio parahaemolytique, Staphylococcus spp. Very sensitive to nifuroxazide: Citrobacter spp, Enterobacter cloacae and Proteus indologenes. Resistant to nifuroxazide: Klebsiella spp, Proteus mirabilis, Providencia spp, Pseudomonas spp.. No effect on saprophytic flora (dysbiosis causes). microbial drug resistance does not develop.
Pharmacokinetics:
Nifuroxazide practically not absorbed from the gastrointestinal tract, 99% of the dose remains in the intestine and exerts its antimicrobial effect there. Nifuroxazide output intestine: 20% unchanged and the remainder nifuroxazide – chemically modified.
Pregnancy and breast-feeding
Pregnancy: animal studies have nifuroxazide showed no teratogenic effects. However, as a precaution, take nifuroxazide during pregnancy is not recommended (insufficient clinical experience in pregnancy).
lactation: during lactation is possible to continue breastfeeding in the case of a short course of treatment with the drug.
Conditions of supply of pharmacies
Without recipe.
side effects
Allergic reactions such as skin rash, urticaria, angioneurotic edema, anaphylactic shock.
special instructions
In the case of bacterial diarrhea with signs of systemic injury (worsening of general condition, fever, symptoms of intoxication or infection) should be used antibacterials with good systemic diffusion. In case of severe, prolonged diarrhea, severe vomiting or refusal of food should be considered intravenous administration of fluids and electrolytes for rehydration. If during treatment with diarrhea persists for more than 2 days, treatment should be reviewed and consider the need to receive fluids and electrolytes into or intravenous administration. The volume of fluid injected and the method of administration (oral, w / w) must match the severity of diarrhea, age and clinical state of the patient.
Possible effects on the ability to drive vehicles or engage in other potentially hazardous activities
The drug has no effect on the ability to drive vehicles or busy with other potentially hazardous activities.
Storage conditions
Stored in a dry place at a temperature not higher than 30 C.
Keep out of the reach of children.
Dosing and Administration
The drug is intended for ingestion by adults or children over the age of 6 years. Adults: 4 capsules (800 mg) per day, divided into 2-4 doses. Children older than 6 years of age: 3-4 capsules (600-800 mg) per day, divided into 2-4 doses. Duration of treatment: no more than 7 days.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist