Ernits tab 10mg 50 pc


Ernits tab 10mg 50 pc



Active substance:
1 tablet contains: Ernits tabletting mass-beads – 0.2475 g, pentaerythrityl tetranitrate containing 10 mg.
Calcium stearate monohydrate – 0.0025 g
Tablets of white color, slightly marble, lenticular shape.
Product form:
Tablets 10 mg. 10 tablets in blisters. 1 or 5 contour cell packages together with instructions for use placed into the package.
Hypersensitivity, severe hypotension (systolic blood pressure below 90 mm Hg. V., Diastolic blood pressure below 60 mm Hg. V.), Collapse, shock, acute myocardial infarction, flowing with hypotension, hemorrhagic stroke, traumatic brain injury, zakratougolnaya glaucoma, severe liver failure (risk of methemoglobinemia), severe renal failure, severe anemia, hypertrophic obstructive cardiomyopathy, constrictive pericarditis, cardiac tamponade, severe stenosis of the aorta experimentally and / or mitral valve, hyperthyroidism, primary pulmonary hypertension (hyperemia insufficiently ventilated alveolar regions may lead to hypoxia), chronic heart failure with low left ventricular filling pressure, simultaneous reception of phosphodiesterase-5 inhibitors (including sildenafil, vardenafil, tadalafil), lactose intolerance and sucrose, sucrase-isomaltase deficiency, lactase or glucose-galactose malabsorption, increased sensitivity to the drug and its components, other organic RTD there, under the age of 18 years (effectiveness and safety have been established).
Apply a tendency to hypotension in the elderly, dehydrated patients; the tendency to orthostatic hypotension in history.
10 mg
Ernits used to prevent angina attacks.
Interaction with other drugs
Together with the admission of the drug with other drugs, consult with your doctor.
Under the influence of dihydroergotamine may reduce the antianginal effect erinita. The combination of these assets is considered unsustainable.
Perhaps greater hypotensive action while applying a vasodilator and antihypertensive agents (beta-blockers, calcium channel blockers, etc.), Antipsychotics, tricyclic antidepressants, monoamine oxidase inhibitors, procainamide, ethanol, 5-phosphodiesterase inhibitors.
Combination with anaprilinom is rational, as anti-anginal action amplifies.
At the use of the drug in high doses may develop tolerance.
Symptoms: orthostatic hypotension, the feeling of compression of the head, throbbing headache, severe sweating, skin cold covered clammy or hyperemic, palpitations, bradycardia, impaired conduction (block), labored respiration, Kussmaul breathing, bloody diarrhea, vomiting, dizziness, confusion, syncope, coma, fever, paralysis, blurred vision.
Treatment: gastric lavage, imparting a horizontal position with the raised feet, with severe arterial hypotension and / or in patients in shock – introduction of fluid into / from a drip infusion solutions, monitoring the level of methemoglobin in the blood by its increasing – assignment of ascorbic acid in a dose of 1 g orally, methylthioninium chloride (methylene blue) / in 50 ml of a 1% solution of toluidine blue – 2 – 4 mg / kg body weight / in quickly, if necessary – again at a dose of 2 mg / kg with intervals of 1 hour , oxygen therapy, hemodialysis, about BMENA transfusion.
pharmachologic effect
Pharmacological group:
Vasodilating agent – nitrate.
Venous vasodilator has antianginal effect. It stimulates the formation of blood vessels in the wall of nitric oxide, which is endothelial relaxing factor. Reduces preload (expansion of peripheral veins and reduced blood flow to the right atrium) and afterload total peripheral vascular resistance (SVR) on the heart; reducing myocardial oxygen demand.
Restores blood flow in small endocardial vessels, improves blood flow in the epicardial coronary arteries, improves exercise tolerance in patients with ischemic heart disease (IHD), angina pectoris.
In heart failure, myocardial unloading contributes by reducing the preload. It reduces the pressure in the pulmonary circulation.
Compared with nitroglycerin, it has a slower but more prolonged action (up to 10 hours). When administered beginning effect – in 30 – 45 min (sublingual – 15 – 20 minutes) duration – 45 hours.
Slowly absorbed by mucous membranes.
Pregnancy and breast-feeding
Use of the drug during pregnancy and lactation is contraindicated.
Conditions of supply of pharmacies
On prescription.
side effects
Allergic reactions, skin flushing, headache, tinnitus, dizziness, nausea, fatigue, tachycardia, fatigue, anxiety, sweating, lowering blood pressure (BP), orthostatic hypotension; sometimes there is a disorder of bowel function (diarrhea). By reducing the dose or upon discontinuation of drug side effects are.
special instructions
When receiving an increased risk of arterial hypotension in elderly patients, dehydrated patients.
Should be excluded in the process of alcohol treatment.
With prolonged use may decrease the therapeutic effect (due to development of tolerance). It recommended to observe “beznitratny” period to reduce the risk of development of tolerance (8 – 12 h).
In applying the drug 1 time per day in combination with other antianginal drugs, the risk of tolerance less.
The drug is not used for the relief of angina attacks. You should not suddenly discontinue treatment with the drug.
Due to the fact that when using the drug may cause side effects such as dizziness, drowsiness and blurred vision, so you must refrain from driving vehicles and activities potentially hazardous activities that require high concentration and rapid mental and motor responses.
Storage conditions
The preparation is stored in a cool, dark place at a temperature not higher than 25 ° C.
Dosing and Administration
Ernits taken orally (per 1 hour before meals) in the form of tablets 10 – 20 mg (1 – 2 tablets) 3 – 4 times a day, if necessary – up to 40 mg four times a day, it is permissible purpose 80 mg 2 times a day.
To prevent nocturnal angina administered 20 mg at bedtime. The course of treatment typically 2 – 4 weeks. Repeated course administered intermittently, the duration of which depends on the course of the disease.
If necessary, possible sublingual drug, but not for relief of angina.
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg


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