Enterol prig.susp.dlya powder for oral 100mg pack. 20 pc

Description

Composition
Active substance:
Saccharomyces boulardii 100 mg of lyophilisate ;.
Excipients:
13 mg of lactose monohydrate, fructose 188.76 mg Colloidal silicon dioxide 2.50 mg, tutti-frutti flavor 1.74 mg.
Description:
Light brown powder with a fruity flavor.
Product form:
Powder for suspension for oral administration 100 mg.
On 306 mg of the powder was placed in a paper-aluminum-polyethylene sachets. 10, 14 or 20 bags together with instructions for use placed into cardboard pack. 10 bags were placed in a cardboard pack without the upper bound and 2 or 5 such packs are placed in a pack carton along with instructions for use.
Contraindications
– hypersensitivity to any component of the drug, in particular lactose or fructose (contains both components in the composition). – Intolerance to lactose, galactose, lactase deficiency (Lapp type) or malabsorption syndrome glucose, galactose or fructose (rare hereditary diseases). – Presence at the patient of central venous catheter.
Dosage
100 mg
Indications
Auxiliary symptomatic treatment and prevention of diarrhea of ​​different etiology in adults and children aged 1 year, including when dysbiosis, irritable bowel syndrome, enterocolitis, antibiotic-associated diarrhea, traveler’s diarrhea, diarrhea caused by Clostridium difficile, used in addition to rehydration.
Interaction with other drugs
Enterol® not take in conjunction with antifungal medications. Compatible with antibiotics.
Overdose
An overdose of the drug is not possible, due to its pharmacokinetic properties.
pharmachologic effect
Pharmacological group:
Antidiarrheals.
Pharmacodynamics:
The preparation Saccharomyces boulardii is a probiotic.
Saccharomyces boulardii has antimicrobial effect due to an antagonistic effect against pathogenic and conditionally pathogenic microorganisms: Clostridium difficile, Candida albicans, Candida kruesei, Candida pseudotropicalis, Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella typhimurium,
Yersinia enterocolitica, Escherichia coli, Shigella dysenteriae, Staphylococcus aureus, and others, as well as Entamoeba histolitica and Lambliae. Saccharomyces boulardii has antitoxin activity against bacterial enterotoxins cyto- and improves enzymatic bowel function. cell wall component mannitol Saccharomyces boulardii is a substrate for pathogenic strains of Escherichia coli and Salmonella typhimurium, which causes their adhesion (attachment) to the surface of Saccharomyces boulardii and subsequent elimination from the body. Saccharomyces boulardii has a natural resistance to antibiotics.
Pharmacokinetics:
Saccharomyces boulardii is not eubiotic because It is not a component of the normal intestinal microflora. Saccharomyces boulardii does not multiply in the digestive tract and is completely eliminated from the body within 2-5 days after discontinuation.
Pregnancy and breast-feeding
No data available.
Conditions of supply of pharmacies
Without a prescription.
side effects
Violations by the immune system
Rare: urticaria.
Very rare: allergic reactions (up to angioedema), rash, itching.
Disorders of the gastrointestinal tract
Common: constipation, flatulence.
Disorders of the nervous system
Common: headache, feeling hot.
special instructions
In children aged 2 to 6 years rehydration may be the primary tool used for the treatment of acute diarrhea. It should be systematically taken into account.
For the prevention or treatment of dehydration is carried oral rehydration therapy.
It is recommended to use solutions provided for this purpose, and to comply with the following conditions: – Na + concentration should be in the range of from 30 to 60 mmol / l. With moderate dehydration apply solutions with lower sodium content (30 mmol / l). – It is necessary to compensate for losses of chlorine and potassium. – Recommended glucose concentration is from 74 to 110 mmol / l. – Addition of hydrolysed proteins or amino acids does not improve the process of rehydration and nutritional status. – It is necessary to offer the baby to drink very often, such as every 15 minutes.
The proposed amount of oral rehydration solution has from about 50 to 100 ml / kg at a loss of 5 to 10% of the body weight due to dehydration.
In the case of severe or prolonged diarrhea, severe vomiting or refusal of oral rehydration, should consider the use of intravenous rehydration.
If after two days of the drug Enterol® diarrhea does not pass, and when the temperature rises, the blood is detected or mucus in the stool you should immediately consult a doctor.
In the appointment of rehydration by receiving rehydration solution for children from 2 to 6 years professional should clearly explain the procedure for its preparation and method of use.
However, when there is no need to appoint rehydration following should be considered: – the child’s need to drink salted or sweet drinks to compensate for fluid loss during diarrhea (average daily rate of fluid intake is 2 liters); – diarrhea should observe the following diet: eliminate raw and unripe fruits and vegetables, spicy dishes, as well as chilled foods and beverages, preferring meals of rice and meat cooked on the grill.
Exception of milk and dairy products from the diet should be considered separately in each case.
It is not recommended to open the bags with the drug in close proximity to patients with a central venous catheter to prevent catheter colonization, in particular, due to contact with hands (see. Also “Contra ‘). This is due to the fact that among patients with a central venous catheter, even those who did not take Saccharomyces boulardii, have been reported very rare cases fungemia, usually expressed by fever and positive blood cultures to Saccharomyces boulardii. In all cases, after application of antifungal therapy and, if necessary, removal of the catheter patients’ condition returned to normal.
Specific action at the first admission of the drug or its cancellation is not provided.
Omitting the reception of one or more doses of medicament further action by the patient’s doctor or a paramedic is required.
Special precautions for the destruction of unused drugs is required.
Effect on ability to drive and use machines:
Enterol® does not affect the ability to drive and use machines.
Storage conditions
At a temperature of 15 to 25 ° C.
Keep out of the reach of children!.
Dosing and Administration
For ingestion. On 2-8 sachets a day 1 hour before meals. Stirred contents of the sachet in a glass of water or other drink room temperature.
Children from 1 year to 3 years – 1-3 sachets twice a day.
Children from 3 years of age and adults – 2-4 sachets twice a day.
Preparation Enterol® contains living cells that are activated at a temperature of 37 ° C, and the drug should not be confused with too hot (above 50 ° C) or cold liquids containing alcohol or food products.
For the treatment of acute diarrhea of ​​viral, bacterial or protozoal etiology treatment is 5-10 days.
In the prevention of antibiotic-associated diarrhea duration of application corresponds to the rate of antibiotic use.
In the prevention of recurrence of infection caused by Clostridium difficile, in combination with metronidazole or vancomycin application duration of 1 month.
In the prevention of travelers’ diarrhea duration of application corresponds to the duration of the trip.
For the treatment of irritable bowel syndrome drug application should continue until symptoms disappear.
Acceptance of the drug for the treatment of acute diarrhea must necessarily be accompanied by rehydration (drinking copious).
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist