Duphaston tab p / 10 mg of the film 28 pc


Duphaston tab p / 10 mg of the film 28 pc

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Active substance:
1 tablet contains: 10 mg dydrogesterone.
Lactose monohydrate; methylhydroxypropylcellulose; corn starch; dye Opadry Y-1-1000 white; colloidal anhydrous silica; magnesium stearate.
Product form:
20 or 28 mg tablets in the blister 10 of aluminum foil and PVC films, uncoated or coated with PVDC, packed in a cardboard box.
Idiosyncrasy of progesterone and other components that make up the drug. Dubin-Johnson syndrome, Rotor syndrome.
10 mg
progesterone deficiency
For the treatment of conditions characterized by deficient progesterone as endometriosis; infertility due to luteal insufficiency; threatening or habitual abortion, associated with the specified deficit of progesterone; premenstrual syndrome; dysmenorrhea; irregular menstruation; secondary amenorrhea; dysfunctional uterine bleeding.
Hormone Replacement Therapy
To neutralize the proliferative effect of estrogens on the endometrium as part of hormone replacement therapy in women with disorders due to natural or surgical menopause with an intact uterus.
Interaction with other drugs
Incompatibilities and interactions with other drugs are known. Inductors microsomal liver enzymes such as phenobarbital, may accelerate metabolism Dyufastona® and weaken its effect.
So far registered no reports of overdose symptoms. When a large overdose recommended gastric lavage. There is no specific antidote, and treatment should be symptomatic.
pharmachologic effect
Pharmacological properties:
Dydrogesterone is a progestogen effective when taken orally, which completely provides the phase advance secretion in the endometrium, thus reducing the risk of endometrial hyperplasia and / or carcinogenesis, increased under the action of estrogen. The drug is indicated in all cases of endogenous progesterone deficiency. Dydrogesterone has no estrogenic, androgenic, thermogenic, corticoids or anabolic activity.
Pregnancy and breast-feeding
The drug can be used during pregnancy.
Dydrogesterone is excreted in breast milk. Dyufastona® Breastfeeding is not recommended during the reception.
Conditions of supply of pharmacies
Available on medical prescription.
side effects
In rare cases, you may experience breakthrough bleeding, which can be prevented by increasing the dose of the drug. During clinical use DYUFASTONA® found no other side effects, including virilizuyuschego effect.
special instructions
Some patients may experience breakthrough bleeding, which, however, can be eliminated by increasing the dose of the drug.
There is a general rule that hormone therapy should not be administered without a general medical examination, including a pelvic examination. Recommended regular mammography.
Abnormal bleeding and lesions revealed during gynecological examination, can serve as an indication to the study of the endometrium.
In combination with estrogen should be used with caution dydrogesterone in patients with impaired renal function, cardiovascular disease, diabetes, epilepsy, migraine.
Dyufaston® not affect the ability to drive a car and control of machines and mechanisms.
Storage conditions
In the dark place at a temperature of from 0 to 30 ° C.
In the reach of children.
Dosing and Administration
Endometriosis 10 mg 2 or 3 times daily from the 5th to 25th day of the cycle or continuously.
Infertility is 10 mg per day from the 14th to 25th day of the cycle. Treatment should be carried out continuously for three or six successive cycles or more.
The treatment is recommended to continue in the first months of pregnancy as well as in habitual abortion.
Threatened abortion 40 mg once, then 10 mg every 8 hours until disappearance of symptoms. After the disappearance of the symptoms continue treatment an effective dose of 1 week. Thereafter, the dosage Dyufastona® gradually reduced. If the symptoms reappear, treatment should be continued using the previous effective dose.
Habitual abortion 10 mg 2 times a day before the 20th week of pregnancy.
Premenstrual syndrome is 10 mg 2 times a day from the 11th to 25th day of the cycle.
Dysmenorrhea 10 mg 2 times a day from 5th to 25th day of the cycle.
Irregular menstruation 10 mg 2 times a day from 11 th to 25 th day of the cycle.
1 estrogenic drug once a day from the 1st to the 25th day of the cycle, together with 10 mg Dyufastona® 2 times a day from the 11th to 25th day of the cycle.
Dysfunctional uterine bleeding (for hemostasis) 10 mg 2 times a day for 5 days or 7 in combination with estrogens.
Dysfunctional uterine bleeding (to prevent bleeding) 10 mg 2 times a day from 11 th to 25 th day of the cycle.
Hormone replacement therapy in combination with estrogens
During continuous estrogen administration schedule – 1 tablet dydrogesterone 10mg daily for 14 days under the 28 day cycle.
When the cyclic regimen of estrogen – 1 tablet of 10 mg dydrogesterone during the last 12-14 days of estrogen.
If ultrasound or biopsy evidence of inadequate response to drug progestogen daily dose of progesterone to be increased to 20 mg.
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg


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