Dramina 50mg tab piece 10 (motion sickness)

Description

Composition
Active substance:
1 tablet contains: 50 mg of dimenhydrinate ;.
Excipients:
Monogidrat- lactose 112.86 mg; microcrystalline cellulose – 57.50 mg magnesium stearate – 1,150 mg; povidone K30 – 4,247 mg; crospovidone – 4,247 mg.
Description:
Tablets white, round shape, flat, bevelled and the notch on one side.
Product form:
Tablets of 50 mg. 5 or 10 tablets in PVC / Al blister. One blister together with instructions for use placed in a cardboard box.
Contraindications
Hypersensitivity to the drug, epilepsy, acute exudative and vesicular dermatitis, children up to 3 years, pregnancy, lactation.
Carefully:
Writhing syndrome, angle-closure glaucoma, prostatic hyperplasia, asthma, cardiovascular diseases, hyperthyroidism, stenosing peptic ulcer, obstruction pyloroduodenal and bladder neck obstruction.
Dosage
50 mg
Indications
motion sickness (nausea, car sickness, air sickness); prevention and treatment of symptoms of vestibular and labyrinth disorders (dizziness, nausea, vomiting), except for the symptoms caused by anticancer therapy; Meniere’s disease.
Interaction with other drugs
It enhances the effects of atropine, tricyclic antidepressants, catecholamines, barbiturates, alcohol, sedatives and hypnotics, neuroleptics, weakens the effect of corticosteroids, anticoagulants. Decreases response to apomorphine. Reduces depressive effect of acetylcholine on the heart muscle. The combination of a bismuth drugs, scopolamine, anesthetics and psychotropic drugs increases the likelihood of visual impairment. Incompatible with ototoxic antibiotics (streptomycin, neomycin, biomycin, amikacin, kanamycin), as may mask the symptoms of ototoxicity and contribute to the development of irreversible hearing loss.
Overdose
Overdose symptoms: dry mouth, nose and throat, redness of the face, slow and labored breathing, confusion in children – seizures, hallucinations. When you see these symptoms should seek immediate medical attention. Treatment: gastric lavage suspension of activated charcoal (20-30 g), the purpose of saline laxative (10-15 g of sodium sulfate), symptomatic therapy, in convulsions in children – phenobarbital (5.6 mg / kg), diazepam.
pharmachologic effect
Pharmacological group:
Gistaminnovyh H1-receptor blocker.
Pharmacodynamics:
Blocking histamine H1 -receptors and M-cholinergic receptors of the central nervous system. Inhibits the vestibular apparatus of the inner ear, working primarily on the otoliths, in high doses – on the semicircular canals. It has antiemetic, anorectic, sedative, mild anti-allergic effect, eliminates dizziness.
Pharmacokinetics:
After oral administration the drug is well absorbed, distributed in organs and tissues. Effect of the drug appears after 15-30 minutes and lasts for 3-6 hours. Almost completely excreted in the urine within 24 hours. Small amounts are excreted in breast milk.
Pregnancy and breast-feeding
Contraindicated (I trimester). Perhaps with extreme caution (II-III trimester), if the effect of therapy outweighs the potential risk to the fetus. At the time of treatment should stop breastfeeding.
Conditions of supply of pharmacies
Without recipe.
side effects
frequency parameters of side effects: very common (> 1/10), common (> 1/100,
special instructions
Given the side effects, caution should be exercised when engaging in potentially hazardous activities that require increased attention and psychomotor speed reactions (including road management).
Storage conditions
At temperatures above 25 ° C, the reach of children.
Dosing and Administration
Inside, the food: motion sickness (sea sickness, car sickness, air sickness): children from 3 to 6 years old – 1/4 1/2 tablet 2-3 times a day; Children from 7 to 12 years – 1/2 -1 tablet 2-3 times a day; Children over 12 and adults – 1-2 tablets 2-3 times a day; prevention and treatment of symptoms of vestibular and labyrinth disorders (dizziness, nausea, vomiting), except for the symptoms caused by antineoplastic therapy: children from 3 to 6 years – 1/4 -1/2 tablets 2-3 times daily; Children from 7 to 12 years – 1/2 -1 tablet 2-3 times a day; Children over 12 and adults – 1-2 tablets 2-3 times a day; Meniere’s disease: c Children 3 to 12 years – 1 / 2-1 tablet 2-3 times a day; Children over 12 and adults 1-2 tablets 2-3 times a day.
The maximum daily dose for adults should not exceed 7 tablets. For the prevention of kinetoses should take 1-2 tablets 30 minutes prior to the trip. Long-term use and the possibility of a repeat course of treatment – in consultation with your doctor.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist