Don tab n / 750mg film about 60 pc

Description

Composition
Active substance:
1 tablet contains: crystalline glucosamine sulfate 942 mg (equivalent to 750 mg of glucosamine sulphate and sodium chloride 192 mg) ;.
Excipients:
Microcrystalline cellulose 68 mg K 25 Povidone (polyvinylpyrrolidone K 25) 45 mg Sodium croscarmellose 20 mg macrogol 6000 (polyethylene glycol 6000) 15 mg Magnesium stearate 8.50 mg Talc 1.50 mg; sheath: methacrylic acid and methyl methacrylate copolymer [1: 1] (Eudragit® L 12.5) 1,0 mg of titanium dioxide particulate 11.50 mg talc 10.55 mg, methylmethacrylate, ethylacrylate trimetilammonioetilmetakrilata chloride copolymer [2: 0.2: 1] (Eudragit RL 30 D) 4,50 mg, triacetin (glycerol triacetate), 0.90 mg of macrogol 6000 (polyethylene glycol 6000) 0.55 mg.
Description:
Elongated oval tablets, coated white. The cross section shows two layers – an outer white, internal – White with yellowish or brownish tint.
Product form:
Film-coated tablet 750 mg.
By 60 and 180 tablets in a plastic bottle with a snap-on lid, along with instructions for use placed in a cardboard box.
Contraindications
Individual sensitivity to the active agent and other ingredients, severe chronic renal failure. We do not recommend use of the drug during pregnancy and lactation, and in children (below 12 years) due to a lack of scientific clinical findings in these patients.
Precautions taken in bronchial asthma and diabetes mellitus.
Dosage
750 mg
Indications
Osteoarthritis of peripheral joints and spine, low back pain.
Interaction with other drugs
Compatible with NSAIDs, corticosteroids and paracetamol. It increases the absorption of tetracyclines reduces – semisynthetic penicillins, chloramphenicol; It enhances the effect of coumarin anticoagulants.
Overdose
Cases of overdose are unknown. Treatment: gastric lavage, symptomatic therapy.
pharmachologic effect
Pharmacological group:
Tissue repair promoter.
Pharmacological properties:
DONA® possesses anti-inflammatory and analgesic effect, replenishes the endogenous glucosamine deficit stimulates the synthesis of proteoglycans and hyaluronic acid synovial fluid; increases the permeability of the joint capsule, restores enzymatic processes in the cells of the synovial membrane and articular cartilage. Promotes fixation of sulfur in the synthesis of chondroitin acid facilitates the normal deposition of calcium in bone tissue, inhibits the development of degenerative processes in the joints, restores their function, reducing joint pain.
Pharmacokinetics:
Absorption in the gastro-intestinal tract 90%, 25% bioavailability, half-life – 70 hours.
Pregnancy and breast-feeding
We do not recommend use of the drug during pregnancy and lactation because of the lack of scientific clinical findings in these patients.
Conditions of supply of pharmacies
Without recipe.
side effects
Good tolerability of the drug. In some cases, possible: gastralgia, flatulence, nausea, diarrhea, constipation; headache, drowsiness; allergic reactions – erythema, urticaria, pruritus.
special instructions
caution should be observed in patients with allergies to seafood (shrimp, clams). The preparation contains 75.5 mg sodium in a tablet that patients should be taken into account, which keep the controlled sodium diet.
When using the drug in patients with impaired glucose tolerance, with severe hepatic or renal insufficiency requires medical supervision.
For information about the possible effects of the drug for medical use on the ability to drive vehicles, mechanisms: the impact is missing.
Storage conditions
Store at a temperature not higher than 25 C.
Keep out of the reach of children.
Dosing and Administration
Inside. 1 tablet of 750 mg taken orally two times a day, preferably during meal time a glass of water. Symptomatic effect after 2-3 weeks after treatment. Minimum course of treatment is 4-6 weeks.
If necessary, repeat the treatment at intervals of 2 months. The duration of the treatment regimen, and appoints doctor.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist