Don Injection 200mg / ml 6 pcs 2ml solvent

Description

Composition
Active substance:
Solution A: each ampoule (2 ml) contains: crystalline glucosamine sulphate 502.5 mg (containing 400 mg of glucosamine sulphate and sodium chloride 102.5 mg);
Solution B: contains no active substances.
Excipients:
Solution A: lidocaine hydrochloride 10.0 mg Water for Injection to 2 ml.
Solution B: diethanolamine – 24.0 mg Water for injection to 1 ml.
Description:
Solution A – colorless or light yellow transparent liquid; solution B – a colorless transparent liquid; plus solution A solution B – light-yellow transparent liquid without suspended particles.
Product form:
A solution for intramuscular injection of 200 mg / ml. 2 ml ampoule A transparent lighting glass, type 1, the ampules are white ring denoting place fracture ampoules.
Solvent. To 1 ml ampoules Bytes transparent colorless glass type 1 ampoule ring have white color, indicating the location of fracture ampoules.
6 vials A PVC plate 6 and ampoules B (solvent) in the PVC plate are placed together with instructions for use in a cardboard box.
Contraindications
Individual hypersensitivity to glucosamine, lidocaine hydrochloride, and other ingredients. Due to the presence of lidocaine in the product, it is contraindicated for patients with cardiac conduction disturbances and acute heart failure, epileptiform convulsions in history, severe liver and kidney; during pregnancy and lactation, and in children under 12 years old.
Carefully.
Precautions should be used drug to patients with chronic heart failure, hypotension. caution should be observed in patients with allergies to seafood (shrimp, clams).
Indications
Primary and secondary osteoarthritis, osteochondrosis, spondylarthrosis.
Interaction with other drugs
Compatible with NSAIDs, corticosteroids and paracetamol.
Care must be taken when assigning injection preparation in combination with beta-blockers, digitoxin, ajmaline, amiodarone, verapamil, quinidine, novokainamidom, geksenalom or sodium thiopental, MAO inhibitors, polymyxin-B, sedatives or hypnotics, cimetidine.
Overdose
Overdose cases are not marked.
pharmachologic effect
Pharmacological group:
Tissue repair promoter.
Pharmacological properties:
DON – anti-inflammatory and analgesic effect, replenishes the endogenous glucosamine deficit stimulates the synthesis of proteoglycans and hyaluronic acid synovial fluid; increases the permeability of the joint capsule, restores enzymatic processes in the cells of the synovial membrane and articular cartilage. Promotes fixation of sulfur in the synthesis of chondroitin acid facilitates the normal deposition of calcium in bone tissue, inhibits the development of degenerative processes in the joints, restores their function, reducing joint pain.
Pharmacokinetics:
In intramuscular bioavailability of 95%, is rapidly spreading in the tissue half-life of about 60 hours is outputted mainly by the kidneys.
Conditions of supply of pharmacies
On prescription.
side effects
Good tolerability of the drug. In some cases, possible: flatulence, diarrhea, constipation, allergic reactions – urticaria, pruritus. Because the content of lidocaine in a formulation can include nausea, vomiting, drowsiness, diplopia, headaches, dizziness, numbness of tongue and oral mucosa, tremor, euphoria, confusion, impaired cardiac conduction.
special instructions
When using the drug in patients with impaired glucose tolerance, with severe hepatic or renal insufficiency requires medical supervision.
Storage conditions
Store at a temperature not higher than 25 ° C.
Keep out of the reach of children.
Dosing and Administration
INTRAMUSCULARLY! The drug is not intended for intravenous administration.
Before using the mixed solution B (solvent) with a solution A (solution formulation) in one syringe.
The prepared drug solution is injected intramuscularly to 3 ml (solutions A + B) 3 times a week for 4-6 weeks. Injection of the drug can be combined with ingestion of the drug in the powder for oral solution (bags).
The duration of the treatment regimen, and appoints doctor.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist