Dolgit gel naruzhn.prim th 5% 50g tube

Description

Composition
Active substance:
100 g of gel contains: active agent 5 g of ibuprofen-
Excipients:
Isopropanol dimetilgidroksimetildioksolan (solketal), poloxamer a; b; c = 101; 56; 101 (Poloxamer 407, Pluronic F 127), srednetsepochnye triglycerides (Miglyol 812), purified water, lavender oil, orange flower oil (nerolovoe oil).
Description:
The clear, colorless gel with characteristic odor.
Product form:
Gel for topical application 5%.
20 g, 50 g or 100 g of gel in an aluminum tube with internal protective lacquer coating, a membrane and a sealed plastic screw-cap.
One tube together with instructions for use placed in a cardboard box.
Contraindications
Hypersensitivity to ibuprofen, the drug component and other NSAIDs; bronchial asthma, urticaria, rhinitis, triggered by reception of acetylsalicylic acid; oozing dermatitis, eczema, destroying the integrity of the skin at the site of gel application, including infected wounds and abrasions; pregnancy (III trimester), children up to 12 years.
Carefully
Pregnancy (I-II trimester), lactation.
Dosage
0.05
Indications
– inflammatory and degenerative diseases of the musculoskeletal system: Articular Syndrome during exacerbation gout, arthritis (rheumatoid, psoriatic, gout), scapulohumeral periarthritis, ankylosing spondylitis (Bechterew’s disease), osteoarthritis deformans, low back pain with radicular syndrome, sciatica, tendonitis, tenosynovitis, bursitis , lumbago, sciatica. – Muscle pain (myalgia), rheumatic and rheumatic origin. – Injury (sports, industrial, household, etc..) Without compromising the integrity of the skin (sprains, strains or tears of muscles and ligaments, bruises, post-traumatic soft tissue swelling, etc.).
Interaction with other drugs
Drug interaction is described with other drugs. However, it should be appreciated that even when applied topically ibuprofen is systemic, and, theoretically, while using the gel with the other NSAIDs may increase side effects.
Overdose
The cases of drug overdose not described.
If you accidentally taking the drug inside is necessary to induce vomiting, gastric lavage, activated charcoal to take. Further treatment, if necessary, symptomatic.
pharmachologic effect
Pharmacological group:
Nonsteroidal anti-inflammatory drug (NSAID).
Pharmacodynamics:
The drug has a local analgesic and anti-inflammatory effect. It suppresses the production of inflammatory mediators. Indiscriminately blocked cyclooxygenase (COX-1 and COX-2) and exerts an inhibitory effect on the synthesis of prostaglandin, prostacyclin and thromboxane. Analgesic effect is most pronounced with inflammatory pain: for pain medication attenuates pain at rest and in motion; reduce morning stiffness and swelling of joints; increases the range of motion. Furthermore anti-inflammatory effect, ibuprofen reduces platelet aggregation at the site of inflammation, and leukocyte migration and release of lysosomal enzymes in the area of ​​inflammation.
Pharmacokinetics:
When applying a gel to the skin ibuprofen penetrates deeper into tissue (subcutaneous tissues, muscles, joints, synovial fluid) and reaches them therapeutic concentrations. The therapeutic effect in the zone of application is achieved by direct distribution through the skin into the target tissue. In small quantities determined in the blood plasma. When the preferred method of application in the synovial fluid concentration – about 2 ug / ml.
Conditions of supply of pharmacies
Without a prescription.
side effects
Usually the drug is well tolerated. In rare cases perhaps temporary signs of local irritation of the skin in the form of redness, swelling, rash, itching, burning sensations and tingling. In the case of hypersensitivity to NSAIDs may be the phenomenon of bronchospasm. Long-term use of the drug in particularly sensitive patients can lead to systemic side effects when they appear, should stop taking the drug and consult a doctor.
special instructions
In severe cases the recommended combined use of a gel externally to the reception of other dosage forms of NSAIDs (parenterally, orally, rectally).
Gel contact should be avoided in the eyes and mucous membranes.
Use of the drug does not affect the activities requiring increased attention, coordination of movements, a high rate of mental and physical reactions (eg, transport drivers, persons who work with complex mechanisms, etc.).
Storage conditions
Stored in a dry place at a temperature of 15-25 C. Keep out of reach of children !.
Dosing and Administration
Outdoor! Gel strip 5-10 cm in length is applied to the damage area thoroughly rubbed lightly until absorbed 3-4 times per day. The duration of treatment depends on the severity of the disease and damage nature, and amounts, on average, 2-3 weeks.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist