Dlyanos Nazal drop. 0.05% 10ml children. fl

Description

Composition
Active substance:
Per 1 ml: 0.5 mg Xylometazoline hydrochloride;
Excipients:
Benzalkonium chloride – 0.11 mg Sodium dihydrogen phosphate dihydrate – 2.8 mg sodium hydrogen phosphate dodecahydrate – 3 mg Disodium edetate – 0.5 mg Sodium chloride – 7 mg Distilled water – up to 1 ml.
Description:
Nasal drops to 0.05% of children as a clear, colorless solution odorless.
Product form:
Drops 10 ml amber glass vials with screw aluminum lid provided with the first opening control system complete with screw cap pipette polypropylene / polystyrene / rubber. Lid – pipette low density packed in a sealed bag made of polyethylene. The bottle with the cap-pipette and instructions for use are placed in a pile of cardboard.
Contraindications
Arterial hypertension; tachycardia; pronounced atherosclerosis; glaucoma; atrophic rhinitis; hyperthyroidism; state after transsphenoidal hypophysectomy; surgical intervention on meninges (in history); pregnancy; Children under 2 years old; Hypersensitivity to xylometazoline and other ingredients.
Dosage
0.5 mg / ml
Indications
Acute respiratory illness with symptoms of rhinitis (common cold); acute allergic rhinitis; hay fever; sinusitis; evstahiit; Otitis media (to minimize swelling of nasal mucosa); Preparing the patient for diagnostic procedures in the nasal passages.
Interaction with other drugs
Xylometazoline is contraindicated in patients receiving monoamine oxidase inhibitors in a given time or receive them during the previous 2 weeks. The simultaneous use of three – or tetracyclic antidepressants and sympathomimetic drugs can lead to increased sympathomimetic effect of xylometazoline, however such combinations should be avoided.
Overdose
Xylometazoline local administration of excessive doses or accidental ingestion can cause severe dizziness, increased sweating, a sharp decrease in body temperature, headache, bradycardia, hypertension, respiratory depression, coma and convulsions. Following the increase in blood pressure can be observed its sharp decline. By appropriate supportive measures should be taken in any suspected overdose, in some cases shown immediate symptomatic treatment under the supervision of a physician. These should include monitoring the patient for several hours. In case of severe poisoning with cardiac arrest CPR should be continued for at least 1 hour.
pharmachologic effect
Pharmacological group:
R01AA07
Pharmacodynamics:
Xylometazoline relates to Grupe local vasoconstrictive agents (decongestants) with a-adrenomimeticheskim action causes vasoconstriction of nasal mucosa, eliminating edema and hyperemia nasopharyngeal mucosa. Xylometazoline also reduces concomitant hypersecretion of mucus and secretions facilitates drainage of blocked nasal passages, and thus improves nasal breathing when nasal congestion. In therapeutic drug concentrations does not irritate the mucous membrane, does not cause flushing. Effect occurs within 2 minutes after application and lasts for 12 hours. In vitro studies have shown that ksilometazolin inhibit the infectious activity of the human rhinovirus, which causes “cold.”
Pharmacokinetics:
When applied topically practically not absorbed, the plasma concentrations below the detection limit.
Pregnancy and breast-feeding
The drug should not be used during pregnancy. During the period of lactation should be used with caution. The drug should only be used after careful assessment of risks and benefits to mother and fetus. It is not allowed to exceed the recommended dosage.
Conditions of supply of pharmacies
Without recipe
side effects
The classification of the frequency of occurrence of adverse effects (WHO): very often> 1/10; often by> 1/100 to
special instructions
Not recommended for use in continuous operation for more than 10 days. Do not exceed the recommended dose, especially in children and the elderly. Long term (over 10 days) or excessive use may cause the effect of “rebound” (rhinitis medicamentosa). The effect on the ability to control vehicle or equipment transoportnym xylometazoline, at dosages higher than recommended, may affect the ability to drive the vehicle or equipment.
Storage conditions
The drug should be kept out of reach of children at a temperature not higher than 30 ° C.
Dosing and Administration
Intranasally. Nasal drops 0.05% indicated for children between 2 and 5 years: 1-2 drops in each nostril 1-3 times / day, should not be used more than 3 times / day. Children from 6 to 11 years old – 2-4 drops in each nostril 2-3 times / day, should not be used more than 3 times / day. The drug in children should be used under adult supervision.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist