Dioksidin injection 1% 10ml amp 10 pcs

$14.28

Dioksidin injection 1% 10ml amp 10 pcs

Quantity:

Description

Composition
Active substance:
1 ml contains: gidroksimetilhinoksalindioksid (dioxidine) -10 mg.
Excipients:
Water for injection – up to 1 ml.
Description:
The transparent greenish-yellow liquid.
Product form:
A solution for intra cavitary and external application of 10 mg / ml.
5 ml or 10 ml in neutral glass ampoules.
3, 5 or 10 vials in blisters of PVC film or tape of polyethylene terephthalate and aluminum foil or polyethylene coated paper with or without foil or without paper.
1 or 2 blisters with instructions for use and a knife for opening ampoules or lancet ampulnam a pile of cardboard.
When packing ampoules fracture ring or fracture point opener ampoules or scarifier ampoule not invest.
Contraindications
Individual drug intolerance, adrenal insufficiency (including history), pregnancy, lactation, infancy (up to 18 years).
Carefully.
Renal insufficiency.
Dosage
1 %
Indications
Purulent bacterial infections caused by sensitive microflora of the ineffectiveness of other chemotherapeutic agents or their poor tolerability.
Intracavitary administration – purulent processes in the thoracic and abdominal cavities with purulent pleuritis, pleural empyema, lung abscess, peritonitis, cystitis, wound with the presence of deep purulent cavities (soft tissue abscesses, phlegmon pelvic tissue, surgical wounds of the urinary and biliary tract purulent mastitis and et al.), for the prevention of infectious complications after catheterization.
External application – superficial and deep wounds of different localization, long-term healing wounds and trophic ulcers, soft tissue cellulitis, infected burns, purulent wounds with osteomyelitis.
Interaction with other drugs
With increased sensitivity to the drug, Dioksidin applied simultaneously with antihistamines or calcium preparations.
Overdose
In case of overdose dioksidina may develop acute adrenal insufficiency, which requires immediate discontinuation of the drug and appropriate hormone replacement therapy.
pharmachologic effect
Pharmacological group:
The antimicrobial agent, quinoxaline.
Pharmacodynamics:
Antibacterial preparation of a wide spectrum of groups quinoxaline derivatives and possesses chemotherapeutic activity against infections caused by Proteus vulgaris, Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli, Shigella dysenteria, Shigella Hexneri, Shigella boydii, Shigella sonnei, Salmonella spp., Staphylococcus spp .. Streptococcus spp., pathogenic anaerobes (Clostridium perfringens), acts on strains of bacteria resistant to other chemotherapeutic drugs, including antibiotics.
Perhaps the development of drug resistance in bacteria. Processing burns and necrotic wounds promotes faster cleansing of the wound and stimulates the reparative regeneration and epithelialization edge and favorably affects the course of wound healing.
Pharmacokinetics:
When applied topically partially sucked from the wound or burn surface, kidneys displayed.
Pregnancy and breast-feeding
During pregnancy and lactation use dioksidina contraindicated.
Conditions of supply of pharmacies
Prescription.
side effects
When intracavitary administration may headache, chills, fever, diarrheal disorders, convulsive muscle contractions, allergic reactions, the photosensitizing effect (appearance of pigmented spots on the body when exposed to sunlight). For exterior use – okoloranevoy dermatitis, pruritus.
special instructions
Dioxidine prescribed only for adults. Before starting the treatment is carried out on a sample of drug tolerance, which is introduced into the cavity 10 ml of a 1% solution. In the absence of a period of 3-6 hours adverse events (dizziness, fever, increased temperature tepa), begin to exchange treatment.
Dioksidin administered only under severe infectious diseases or the ineffectiveness of other antibacterial drugs, including cephalosporins of generations II-IV, fluoroquinolones, carbapenems.
In chronic renal failure dose reduced.
When pigmented spots prolong the dose of 1.5-2 hours, reduce the dose or prescribe antihistamines cancel Dioksidin.
In case of loss of crystals during storage (at a temperature below 15 ° C), they are dissolved by warming the ampoule in a boiling water bath with shaking until crystals dissolve (clear solution). If upon cooling to 36-38 ° C the crystals will not fall again, the drug is fit for use.
The possible effect of the drug on the ability to drive vehicles, mechanisms:
During the period of treatment must be careful when driving and occupation of other potentially hazardous activities that require high concentration and psychomotor speed reactions.
Storage conditions
In the dark place at a temperature of from 15 to 25 ° C.
Keep out of the reach of children.
Dosing and Administration
Dioxidine administered in a hospital environment. Applied externally, intracisternally. 1% solution Dioxydinum can not be used for intravenous administration due to storage at low temperature instability of the solution.
Intracavitary administration.
The purulent cavity depending on its size administered per day from 10 to 50 ml of a 1% solution Dioxydinum. Dioxydinum solution is introduced into the cavity through the catheter, drainage tube or syringe.
The maximum daily dose for oral administration to – 70 ml of a 1% solution.
The drug is injected into the cavity is typically once a day. By indications may administering a daily dose in two steps. With good tolerance drug can be administered daily for 3 weeks or more. If necessary, after 1-1.5 months to repeat courses.
External application.
Apply 0.1-1% solutions Dioxydinum. For solutions of 0.1-0.2% solutions ampoule preparation diluted to a desired concentration with sterile 0.9% sodium chloride solution or water for injection. For the treatment of superficial infected purulent wounds at the wound superimposed wipes moistened with a solution of 0.5-1% Dioxydinum. Deep wounds after treatment loosely tamponiruyut swabs moistened Dioxydinum 1% solution, and in the presence of a drainage tube is introduced into the cavity of from 20 to 100 ml of 0.5% drug solution.
For the treatment of deep wounds with purulent osteomyelitis (wounds hand, foot) apply 0.5-1% solutions of the drug in the form of trays or conduct special processing wounds drug solution within 15 20 minutes (the introduction of the solution into the wound in this period), followed by the imposition dressing with 1% solution Dioxydinum.
Dioksidin as 0.1-0.5% solutions can be used for prevention and treatment of infection after surgery. According to the testimony (patients with osteomyelitis) and good tolerability, treatment can be done every day for 1.5-2 months.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg
Manufacturer

Valenta Pharm

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