Dimexide gel appearance. 25% 30g tuba

Description

Composition
Active substance:
Dimexidum (DMSO) 25.0 g
Excipients:
Methyl parahydroxybenzoate (Nipagin) 0.050 g propyl parahydroxybenzoate (Nipasol) 0.013 g, carmellose sodium (sodium carboxymethylcellulose) 2.0 g purified water ad 100.0 g
Description:
The antiinflammatory agent for external use.
Product form:
Tuba ’30
Contraindications
Hypersensitivity to Dimexidum or other ingredients, pregnancy, lactation, severe liver disease and kidney failure, angina, myocardial infarction, arteriosclerosis expressed, various types of stroke, glaucoma, cataracts, coma, children up to 12 years.
Dosage
25%
Indications
Used for pain relief in complex therapy of rheumatoid arthritis, ankylosing spondylitis, osteoarthritis deformans, arthropathy, sciatica, trigeminal neuralgia et al., For the treatment of contusions, ligament damage, traumatic infiltrates in the treatment of erythema nodosum.
pharmachologic effect
Pharmacodynamics:
The anti-inflammatory agent with analgesic and local anti-inflammatory action. It has mild antiseptic, and fibrinolytic effect. Dimethyl sulfoxide inhibits inflammatory infiltration of tissues. Furthermore, dimethylsulfoxide fibrin contributes to the normalization process. Dimethylsulfoxide enhances microcirculation in tissues by inhibiting the aggregation of red blood cells increases the phagocyte activity inhibits chemotaxis of neutrophils and reduces the circulating immune complexes. Penetrates through the skin, mucous membranes, the cell wall of bacteria (increases their sensitivity to antibiotics) and other biological membranes, increases their permeability to drugs. The drug has low toxicity.
Pharmacokinetics:
In applications dimethylsulfoxide drug detected in the serum after 8-15 minutes, and the maximum content observed after 2-8 hours. As a rule, after 30-36 hours of dimethyl sulfoxide in the serum is no longer detected. Dimethyl sulfoxide not accumulates. The local application of the drug dimethylsulfoxide penetrates into the joint cavity, blood and tissues associated with the protein. Dimethylsulfoxide excreted unchanged via the kidneys and in the form of oxidation products – dimethyl sulfone and dimethyl sulfate; as well as a reduced product (dimethyl) excreted in expired air.
side effects
In use, the drug may be a contact dermatitis, garlic odor of breath, increased skin pigmentation, allergic reactions, erythematous rash, dry skin, slight burning. Some patients perceived bad odor of the drug (such as nausea, retching), and in rare cases possible bronchospasm. If any of these instructions side effects are compounded or you notice any other side effects not mentioned in the instructions, tell your doctor.
special instructions
Given the possibility of individual intolerance of the drug, it is recommended to carry out drug test for tolerance to it. To this thin layer of gel is applied to the skin of the elbow. The appearance of a sharp redness and itching indicates hypersensitivity to Dimexidum. If there during drug treatment of allergic reactions, use of the drug is stopped blockers administered H1-histamine receptor.
Storage conditions
Store at room temperature of 15-25 degrees.
Dosing and Administration
Outwardly. Adults and children over 12 years, the drug is applied thinly to the affected area 1-2 times a day. The duration of treatment 10-14 days. Repeated courses may be held not less than 10 days.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist