Dexpanthenol ointment 5% vertex 30g tuba

Description

Composition
Active substance:
Dexpanthenol – 50.0 mg ;.
Excipients:
White soft paraffin (white petrolatum, petrolatum) – 270.0 mg; lanolin (anhydrous lanolin) – 170.0 mg; Liquid paraffin (mineral oil, liquid petrolatum) – 100.0 mg; isopropyl – 30.0 mg; cholesterol (cholesterol) – 5.0 mg; methyl parahydroxybenzoate (methyl paraben, Nipagin) – 0.7 mg; propyl parahydroxybenzoate (propylparaben, Nipasol) – 0.3 mg; Purified water – 1.0 g
Description:
Homogeneous ointment of light yellow color with a characteristic odor of lanolin.
Product form:
Ointment for external use 5%. 30 g in a tube of aluminum.
Each tube together with instructions for use placed in a pile of cardboard.
Contraindications
Hypersensitivity to any component of the drug.
Dosage
5 %
Indications
– violations integrity of the skin caused by mechanical, chemical, thermal factors or after surgery: – burns of various origins (including solar); – scratches, abrasions, wounds, pressure sores; – poorly healing skin grafts; – aseptic surgical wounds; – inflammation of the skin: dermatitis, boils, venous leg ulcers; – Skin care around the tracheostomy, gastrostomy tube and colostomy; – treatment and prevention of adverse effects to skin environmental factors (cold, wind, moisture); – children: nappy rash, skin irritation, treatment and prevention of diaper rash; y nursing mothers – cracks and inflammation of the breast nipples; – treatment and protection of dry skin as a source of neutral fats and dexpanthenol.
Interaction with other drugs
Cases of interaction with other drugs for external use are not known.
Overdose
No cases of overdose have been reported.
pharmachologic effect
Pharmacological group:
Tissue repair promoter.
Pharmacodynamics:
Dexpanthenol – a derivative of pantothenic acid. Pantothenic acid – water-soluble vitamin of group B (Vitamin B5) – is a component of coenzyme A. It stimulates the regeneration of the skin, normalize cellular metabolism, increases the strength of collagen fibers. Increasing demand for pantothenic acid is observed for damaged skin or tissue, and it can make up for lack of local application of dexpanthenol. The optimal molecular weight, hydrophilicity and low polarity enable its penetration into all layers of the skin. Provides regenerating, weak anti-inflammatory action.
Pharmacokinetics:
Absorption, distribution
When applied topically rapidly absorbed and converted into pantothenic acid, binds to plasma proteins (mostly with beta-globulin and albumin). pantothenic acid concentration in blood of 0.5-1 mg / liter in blood plasma – 100 g / l.
Metabolism, excretion
Pantothenic acid is not subjected to metabolism in the body and excreted unchanged by the kidneys.
Pregnancy and breast-feeding
Dexpanthenol The drug can be used during pregnancy and lactation.
Conditions of supply of pharmacies
Without a prescription.
side effects
Allergic reactions (including delayed due to the presence of the drug parahydroxybenzoate) – urticaria, pruritus.
If any of these instructions side effects are compounded, or observed any other side effects not mentioned in the instructions, you should immediately inform your doctor.
special instructions
Treatment of venous ulcers and poorly healing skin grafts should be under the supervision of a doctor.
Do not apply to oozing wounds.
Avoid contact with eyes.
Effects on ability to drive vehicles and mechanisms:
Dexpanthenol The drug has no effect on ability to drive and use machines.
Storage conditions
Store at a temperature not higher than 25 ° C.
Keep out of the reach of children.
Dosing and Administration
Outwardly.
The ointment is applied 2-4 times a day (more if necessary).
Apply a thin layer to the affected area of ​​the skin, gently rubbing. In the case of application to the infected area of ​​the skin, it must be pre-treated by any antiseptic.
Nursing mothers to lubricate the surface of the nipple ointment after each breastfeeding.
Infants applied ointment after each change of underwear or water treatments.
Long-term use and the possibility of repeating the course of treatment depend on the individual characteristics of the disease in the patient and identifies reached therapeutic effect and tolerability.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist