Detraleks oral suspension 1000mg / 10ml 10ml sachet 30 pcs

Description

Composition
Active substance:
1 sachet (10 ml) contains: micronized purified flavonoid fraction is 1000 mg, containing diosmin 900.0 mg (90%) and flavonoids, hesperidin, based on 100.0 mg (10%).
Excipients:
Citric acid 12.5 mg, 15.0 mg of orange flavoring, maltitol 1800.0 mg Sodium benzoate 15.0 mg, 50.0 mg xanthan gum, purified water q.s. to 10 ml.
Description:
Uniform suspension of light yellow color with a characteristic odor.
Product form:
A suspension for oral administration, 1,000 mg / 10 ml.
10 ml of a suspension for ingestion into multilayer sachets (polyester, aluminum, polyethylene). 15 or 30 together with instructions sachet for medical use in a cardboard pack.
Contraindications
Hypersensitivity to the active substance or auxiliary substances included in the preparation.
Fructose intolerance.
We do not recommend the drug to nursing women.
Dosage
1000 mg
Indications
Detraleks® indicated for the treatment of chronic venous disease symptoms (elimination and the relief of symptoms).
Therapy symptoms venous-lymphatic insufficiency: – pain; – spasms of the lower limbs; – a feeling of heaviness and fullness in the legs; – “tired” legs.
Therapy manifestations of venous-lymphatic insufficiency: edema of the lower extremities; trophic changes in the skin and subcutaneous tissue; venous trophic ulcers.
Symptomatic treatment of acute and chronic hemorrhoids.
Interaction with other drugs
Not mentioned.
Should inform your doctor about any
You are taking medications.
Overdose
Overdose is not described.
If overdose seek immediate medical attention.
pharmachologic effect
Pharmacological group:
Venotoniziruyuschee and venoprotektornoe means.
Pharmacodynamics:
Detraleks® has angioproteguoe and venotonic properties.
The drug reduces the extensibility of the veins and venous stasis, reduces the permeability of capillaries and improves their resistance. Results of clinical studies confirm the pharmacological activity of the drug against venous hemodynamic indices.
A statistically significant dose-dependent effect of the drug was demonstrated Detraleks® following venous plethysmographic parameters: venous capacity, venous distensibility, venous emptying time. The optimum ratio of “dose-effect” is observed when receiving 1000 mg per day.
Detraleks® increases venous tone: using venous occlusion plethysmography been shown to decrease venous emptying time. Patients with signs of pronounced microcirculatory disorders, post-treatment drug. Detraleks® marked (statistically significant compared to placebo) increasing capillary resistance estimated by angiostereometrii.
Detraleks® proved the therapeutic efficacy of the drug in the treatment of chronic diseases of the lower limbs, as well as in the treatment of hemorrhoids.
Detraleks® reduces unwanted side effects of invasive treatments HZV (reduces the incidence of unwanted side effects at surgical and endovascular treatment of varicosity: significantly reduces the intensity of postoperative pain, edema and hemorrhages severity and after endovascular surgery).
Pharmacokinetics:
Main drug selection occurs in the faeces. The urine, on average, about 14% output the received amount of the drug.
half-life is 11 hours.
The drug undergoes active metabolism, which is confirmed by the presence of phenolic acids in the urine.
Pregnancy and breast-feeding
Pregnancy
Animal experiments did not reveal any teratogenic effects.
Until now there has been no reports of adverse effects when using the drug in pregnant women.
Breastfeeding
Due to lack of data on the excretion of the drug in breast milk, breast-feeding women are not recommended to take the drug.
Effects on reproduction
Reproductive toxicity studies have not shown effects on reproductive function in rats of both sexes.
Conditions of supply of pharmacies
Without a prescription.
side effects
Side effects of the drug Detraleks® observed in clinical trials were mild degree. Advantageously marked disorders of the gastrointestinal (diarrhea, dyspepsia, nausea, vomiting).
At the time of taking the drug Detraleks® reported the following side effects in the form of the following gradation: very common (> 1/10); common (> 1/100,
special instructions
– Before you start taking the drug Detraleks®, it is recommended to consult a doctor. – In acute hemorrhoids Detraleks® use of the drug does not replace specific treatment other anal disorders.
The duration of treatment should not exceed the time specified in the “Method of administration and dose.” In that case, if the symptoms do not disappear after the recommended course of treatment, should be examined by a proctologist, who will pick up further therapy. – If venous circulation disorders maximum treatment effect provided by a combination therapy with a healthy (balanced) lifestyle; it is desirable to avoid a long stay in the sun longer stay on his feet, and recommended reduction of overweight. Hiking and, in some cases, wearing special stockings (compression stockings) help to improve blood circulation.
Immediately contact your doctor if you are in the process of treating your condition worse or no improvement.
Effects on ability to drive and perform work requiring a high rate of mental and physical reactions
Does not affect.
Storage conditions
Store at a temperature not higher than 30 ° C.
Keep out of the reach of children.
Dosing and Administration
Inside.
The recommended dose for venous-lymphatic insufficiency – 1000 mg (1 sachet contents) per day, preferably in the morning at mealtimes.
The duration of treatment may last several months (up to 12 months). In the case of recurrence of symptoms, on doctor’s advice, treatment can be repeated.
The recommended dose for acute hemorrhoid – 3000 mg per day (1000 mg (the contents of one sachet) in the morning, afternoon and night) for 4 days, then to 2000 mg per day (1000 mg (the contents of one sachet) in the morning and evening) over the next 3 days.
The recommended dose for chronic hemorrhoids – 1000 mg (1 sachet contents) per day at any time of the day together with a meal.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist