Dentamet Gel 25g

Description

Composition
Active substance:
Metronidazole – 1.00 g
Chlorhexidine bigluconate 20% solution – 0.50 g, calculated as chlorhexidine digluconate – 0.10 g
Excipients:
Levomenthol (L-menthol) – 0.25 g
Glycerol (glycerin) – 5.00 g
Propylene glycol – 5.00 g
Trolamine (triethanolamine thermostable) – 0.47 g
Carbomer – 1.25 g
Sodium saccharine dihydrate – 0.25 g
Purified Water – 86.28 g
Description:
Homogeneous gel, from white to white with a yellowish tinge.
Product form:
Dental Gel.
25 g aluminum tubes. Each tube together with instructions for use placed in a pile of cardboard.
Contraindications
– hypersensitivity to metronidazole, chlorhexidine, nitroimidazole derivatives or other components of the formulation;
– disease of the blood system, including a history;
– disorders of the peripheral and central nervous system;
– Children up to age 18 years.
Indications
Infectious inflammatory periodontal disease and oral mucosa:
– acute and chronic gingivitis;
– acute necrotizing ulcerative gingivitis Vincennes;
– acute and chronic periodontitis;
– periodontal disease, gingivitis complicated;
– aphthous stomatitis;
– cheilitis;
– inflammation of the oral mucosa when wearing dentures;
– post-extraction alveolitis (inflammation after tooth extraction wells);
– periodontitis, periodontal abscess (in combination therapy).
Interaction with other drugs
The local application at the recommended doses gel Dentamet system interaction with other drugs is not revealed.
Overdose
Drug overdose cases the topical application were observed.
pharmachologic effect
Pharmacological group:
The antimicrobial agent.
Pharmacodynamics:
Combined antimicrobial. Efficacy of the drug due to the presence in its composition of active ingredients as metronidazole and chlorhexidine.
Metronidazole – derivative nitroimidazole having antiprotozoal and antibacterial action against anaerobic protozoa and anaerobic bacteria causing periodontal disease: Porphyromonas gingivalis, Prevotella intermedia, Prevotella denticola, Fusobacterium fusiformis, Wolinella recta, Treponema spp, Eikenella corrodens, Borrelia vincenti, Bacteroides melaninogenicus, Selenomonas. spp. Not against aerobic bacteria.
The mechanism of action is in the biochemical reduction of 5-nitro group of metronidazole intracellular transport proteins of anaerobic microorganisms and protozoa. The recovered 5-nitro group of metronidazole is reacted with DNA of microbial cells, inhibiting synthesis of nucleic acids, which leads to the death of the bacteria.
Chlorhexidine – antiseptic exhibits against Gram-positive and Gram-negative bacteria bactericidal effect, has fungicidal and virucidal effect (against lipophilic viruses). In bacterial spores only operates at an elevated temperature.
Effective against gram-positive and gram-negative bacteria (including (Treponema spp., Neisseria gonorrhoeae, Chlamidia spp.)), Viruses and fungi.
Pharmacokinetics:
For topical application the active substances substantially do not undergo systemic absorption and have no systemic action.
Pregnancy and breast-feeding
In the absence of clinical data, safety of the drug during pregnancy and lactation has not been established. It is not recommended to use the drug during pregnancy.
During the period of breast-feeding should decide the issue of termination of breastfeeding, if necessary, the appointment of the drug.
Conditions of supply of pharmacies
Without a prescription.
side effects
When applied topically, the gel can sometimes be observed Dentamet “metallic” aftertaste in the mouth, headache, allergic reactions (rash, pruritus, urticaria, anaphylactic reactions, including anaphylactic shock).
If any of these instructions side effects are compounded, or you notice other effects not listed in the instructions, tell your doctor.
special instructions
Avoid contact with eyes.
Application of the gel does not replace the sanitary Dentamet dentifrice, so during the time course of drug treatment cleaning needs to be continued.
The drug should be stored out of reach of children. In case of accidental or deliberate ingestion of the drug a child should immediately seek medical help.
Effects on ability to drive and use machines
No negative impact on the data.
Storage conditions
At temperatures above 25 ° C.
Keep out of the reach of children.
Dosing and Administration
Locally, only for dental applications.
When inflammation of the gums (gingivitis)
Dentamet applied to the gum region or a thin layer of a finger using a cotton swab 2 times per day. After application of the gel should refrain from drinking and eating for 30 min. Rinse off the gel is not recommended.
Duration of treatment is usually 7-10 days.
When periodontitis:
After removal of dental plaque, periodontal pockets treated Dentamet gel, and the gel is made on application area gums. Exposure – 30 min. A number of treatments depends on the severity of the disease. In the future application of the gel the patient can hold their own.
Dentamet applied to the area of ​​the gums 2 times a day for 7-10 days.
If canker sores:
Dentamet applied to the affected area of ​​the oral mucosa 2 times a day for 7-10 days.
For the prevention of exacerbations of chronic gingivitis and periodontitis:
Dentamet applied to the area of ​​the gums 2 times a day for 7-10 days.
Preventive treatments are carried out 2-3 times a year.
For the prevention of alveolitis postekstratsionnogo:
After tooth extraction hole Dentamet processed gel, then the gel is applied 2-3 times a day for 7-10 days.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist