Complivit calcium q3 prig.susp.dlya powder for oral administration to babies 50me + 200mg / 5ml vial 1 piece 43g

Description

Composition
Active substance:
5 ml of suspension contains: calcium carbonate (in terms of calcium) – 500 mg (200 mg); Kolekaltsiferol (based on 100% Kolekaltsiferol) – 0.00135 mg (50 ME), in the form of granules comprising: Kolekaltsiferol, D, L-alpha tocopherol, medium-chain triglycerides, sucrose, acacia, corn starch, calcium phosphate, water .
Excipients:
Sorbitol (sorbitol), 1,479 g, pregelatinized starch (predzhel) – 0.15 g, colloidal silicon dioxide (Aerosil) – 0.0108 g Orange flavoring – 0,01 g
Description:
The powder is white or off-white color with a characteristic smell of orange.
The homogeneous suspension of white or off-white color with a characteristic smell of orange.
Product form:
powder for suspension for oral administration of 200 mg + 50 IU / 5 ml.
According to 43.0 g in 100 ml flasks on a dark (amber) glass. One vial together with instructions for use and the measuring spoon is placed in a pile of cardboard.
Contraindications
Hypersensitivity, hypercalcemia, hypercalciuria, calcium nefrourolitiaz, hypervitaminosis D, tumors decalcifying (myeloma, bone metastases, sarcoidosis) and osteoporosis due to immobilization, the active form of tuberculosis; deficit sucrase / isomaltase, fructose intolerance, glucose-galactose malabsorption.
CAREFULLY
Renal failure, benign granulomatosis, cardiac glycosides and receiving thiazide diuretics, pregnancy, lactation.
Indications
Prevention of calcium and vitamin D3 deficiency in infants.
Interaction with other drugs
Calcium and vitamin D3 reduces the absorption of bisphosphonates, digoxin, iron and antibiotics tetratsikpinovogo number (required between drug administration for at least 2-3 hours).
Possible potentiation of cardiac glycosides (while receiving necessary ECG monitoring and patient).
Phenytoin, barbiturates, primidone reduce the effect of vitamin D3 by increasing its metabolism.
Vitamin A, tocopherol, ascorbic acid, pantothenic acid, thiamine, riboflavin attenuate the toxic effects of vitamin D3.
Glucocorticosteroids reduce the absorption of calcium in the intestine.
Cholestyramine, colestipol and mineral oil reduces the absorption of vitamin D3 and require increasing its dosage.
Thiazide diuretics increase the risk of hypercalcemia.
Vitamin D increases the absorption of phosphorus-containing drugs and the risk of hyperphosphataemia. While the use of sodium fluoride interval between doses should be at least 2 hours; forms with oral tetracyclines -. at least 3 hours vitamin D3 Long-term therapy on the background of the simultaneous application of Al3 + and Mg2 + – containing antacid increases their concentration in the blood and the risk of toxicity (especially in the presence of CRF).
The simultaneous use of other analogues of vitamin D and calcium supplementation increases the risk of hypervitaminosis D.
Overdose
Symptoms: thirst, polyuria, loss of appetite, nausea, vomiting, constipation, dizziness, weakness, headache, fainting, coma; with prolonged use calcification of vessels and tissues.
Laboratory findings in overdose: hypercalciuria, hypercalcemia.
Treatment: discontinuation of the drug, access to a doctor, a diet with calcium restriction, rehydration, diuretics, steroids, in severe cases – hemodialysis.
pharmachologic effect
Pharmacological group:
Calcium-phosphorus metabolism regulator.
Pharmacological properties:
Combined preparation intended to compensate for deficiency of calcium and vitamin D3 in the body.
Pharmacokinetics:
Calcium is involved in bone formation, increases its density, is involved in mineralization of the teeth, in nerve conduction and the regulation of muscle contraction, in maintaining cardiac stability in the blood clotting process.
Vitamin D3 (Kolekaltsiferol) regulates the exchange of calcium and phosphorus in the body, increases calcium absorption in the intestine promotes bone mineralization, bone formation of skeletal and teeth in children. The drug reduces the production of parathyroid hormone, which is a stimulator of increased bone resorption.
Pregnancy and breast-feeding
During pregnancy and lactation is possible to use the drug on a doctor’s recommendation.
The daily dose should not exceed 1500 mg calcium and 600 ME vitamin D3.
Hypercalcemia on the background of an overdose and excessive intake of vitamin D3 during pregnancy may have adverse effects on the developing fetus.
Calcium and vitamin D3 can penetrate into breast milk, while taking the drug so the mother during the breast-feeding is necessary to consider the calcium and vitamin D intake from other sources.
Conditions of supply of pharmacies
Without recipe.
side effects
Allergic reactions. In applying the drug at the recommended doses of other side effects were detected. When exceeding the recommended doses, or simultaneous administration of other drugs containing calcium may develop hypercalcemia and hypercalciuria (high content of calcium in the blood and urine).
Possible side effects of vitamin D3 and include decreased appetite, polyuria, constipation, headache, myalgia, arthralgia, increased blood pressure, arrhythmia, renal failure, worsening of tuberculosis in the lungs.
Possible side effects of calcium carbonate also include gastralgia, diarrhea or constipation, flatulence, nausea, secondary amplification gastric secretion.
special instructions
To avoid overdose are not used in conjunction with vitamin complexes, containing calcium and vitamin D3.
When prophylactic use of vitamin D3 should be borne in mind the possibility of an overdose, especially in children (should not be administered more than 10-15 mg per year). Prolonged use of high doses leads to chronic hypervitaminosis D3. Prolonged treatment is necessary to control the concentration of Ca2 + in the blood and urine (especially when combined with thiazide diuretics).
It should be borne in mind that the sensitivity to vitamin D in different patient individually, and in some patients receiving therapeutic doses even can cause the phenomenon of hypervitaminosis.
The sensitivity of infants to vitamin D may be different, some may be sensitive even to very low doses, so prevention should be carried out under the supervision of a physician. Babies who are breastfed, especially born to mothers with dark skin and / or do not get enough sun exposure, have a high risk of deficiency of vitamin D.
Effects on ability to drive a vehicle, the mechanism
Data on the effect of the drug on driving ability and the performance of potentially hazardous activities that require high concentration and psychomotor speed reactions, no.
Storage conditions
Store at a temperature not higher than 25 ° C.
The obtained suspension is kept at a temperature not higher than 15 ° C (in a refrigerator). Do not freeze.
Keep out of the reach of children.
Dosing and Administration
The drug is taken orally, at meal time. The dosage form is especially designed for young children up to 3 years.
Preparation of slurry from powder: Before preparing the slurry vial containing a powder, shaken well for separating the powder particles from the bottom and walls to add boiled and cooled water to 2/3 volume of the vial carefully shaken (for 1-2 minutes). Add boiled water to 100 ml (before the bottle neck) and re-shaken until a homogeneous suspension.
Before each reception stir the contents of the vial.
In 5 ml of the resulting suspension contained calcium carbonate in terms of elemental calcium – 200 mg, kolekaltsiferola – 50 ME.
Children under the age of 1 year – 5.10 ml of 1 time per day; children under 1 year – 5 ml suspension of 1 times a day, on doctor’s advice. Dosage adjustment for other age groups – in accordance with the doctor’s recommendations.
Duration of course of treatment – 1 month, longer course – on doctor’s orders.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist