Coldrex with vitamin C Table 12 pieces in a compact package

Description

Composition
Active substance:
1 tablet contains 500.00 mg of paracetamol, ascorbate 30.00 mg, 25.00 mg of caffeine, terpin hydrate 20.00 mg phenylephrine hydrochloride, 5.00 mg.
Excipients:
Corn Starch – 103.5 mg pregelatinized starch – 30.0 mg talc – 12.47 mg stearic acid – 6.24 mg, povidone – 4.0 mg of potassium sorbate – 0.8 mg Sodium lauryl sulfate – 0 , 8 mg, sunset yellow dye (E110) – 0,4 mg.
Description:
Kapsulovidnye bilayer tablets, one layer of orange, another layer of white. Opanzhevy cloy mozhet coderzhat belye are on. Bely cloy mozhet codepzhat opanzhevye are on. Ha Odno ctopone tabletki nanecena mapkipovka Coldrex in RESIDENCE ticneniya.
Product form:
Tabletki. Po 6 or 12 in tabletok blictepax (pvx / alyuminievaya folga). 1 or 2 blictepa (6 or 12 tablets each) vmecte c inctpyktsiey Po ppimeneniyu kaptonnyyu placed in a stack.
Contraindications
Ppeparat ne cledyet ppinimat VARIATIONS povyshennoy chyvctvitelnocti to components vxodyaschim in coctav ppeparata at geneticheckom otcytctvii glucose-6-focfat degidrogenazy at zabolevaniyax cictemy kpovi at tyazhelyx napysheniyax fynktsii pecheni or pochek, tireotokcikoze, diabete, apterialnoy hypertension, alcoholism, simultaneously with inhibitors MAO and for 14 days after their withdrawal (see “Interaction with other drugs.”); during pregnancy and lactation, as well as children (under 12 years).
Be wary – if angle-closure glaucoma, prostatic hyperplasia; congenital hyperbilirubinemia (Gilbert’s syndrome, Dubin-Johnson and Rotor), pheochromocytoma, vasospastic diseases (Raynaud’s syndrome), diseases of the cardiovascular system.
Indications
Tabletki “Koldrekc” obecpechivayut yctpanenie cimptomov “cold” and gpippa, takix HOW povyshennaya temperatyra, golovnaya pain, chills, sore cyctavax and myshtsax, oschyschenie zalozhennocti noca, pain pazuxax noca and gorle.
Interaction with other drugs
The drug should not be taken concurrently with tricyclic antidepressants, beta-blockers and other antihypertensive agents, as well as a sympathomimetic, as increases the risk of hypertension and other disorders of the cardiovascular system.
Do not take simultaneously with MAO inhibitors and within 14 days after their withdrawal as increasing the risk of developing hypertension.
When concomitantly with digoxin and cardiac glycosides may increase the risk of heart rhythm disorders or heart attack.
Anticoagulant effect of warfarin and other coumarins may be enhanced, while prolonged regular daily use of paracetamol with increased risk of bleeding. Irregular administration of a single dose has no significant effect.
The risk of hepatotoxicity is increased while taking barbiturates, diphenylhydantoin, carbamazepine, rifampicin, AZT, and other inducers of microsomal liver enzymes.
Consult with your doctor if you are taking metoclopramide, domperidone (used to treat nausea and vomiting) or cholestyramine (used to lower cholesterol in the blood), because metoclopramide and domperidone to increase the rate of absorption of paracetamol, and cholestyramine reduces.
Overdose
If you suspect an overdose, even in good health, you must stop using the product immediately and seek medical help.
Symptoms (caused by paracetamol): pale skin, loss of appetite, nausea, vomiting; hepatic failure, gepatonekroz (severity of necrosis due to toxicity is directly dependent on the degree overdose). Toxic effects in adults is possible after receiving more than 10-15 g of paracetamol: increased activity “liver” transaminases, clinical liver disease is manifested after 1-6 days. Rarely hepatic insufficiency develops lightning and can be complicated by renal insufficiency (tubular necrosis).
Treatment: gastric lavage, followed by activated carbon, the introduction donators SH-groups and precursors of glutathione synthesis – methionine through 8-9 hours after the overdose and N-acetylcysteine ​​- 12 hours.
Symptoms (due to caffeine): epigastric pain, vomiting, frequent urination, tachycardia, arrhythmia, CNS stimulation (insomnia, anxiety, irritability, anxiety, increased neuro-reflex excitability, tremors, and convulsions). It should however be borne in mind that the occurrence of clinically significant symptoms of caffeine overdose while taking this drug is always associated with severe liver injury caused by paracetamol overdose.
Treatment: symptomatic, there is no specific antidote.
Symptoms (due phenylephrine): irritability, headache, dizziness, insomnia, high blood pressure, nausea, vomiting, anxiety, reflex bradycardia. In severe cases an overdose may develop hallucinations, confusion, seizures, arrhythmias.
Treatment: symptomatic therapy, with severe hypertension use alpha blockers, such as phentolamine.
Symptoms (due to ascorbic acid): high doses of ascorbic acid (3000 mg) can cause osmotic diarrhea, and the temporary disruption of the gastrointestinal tract, such as nausea, discomfort in the stomach area. Manifestations of overdose can be categorized as those that cause severe liver disease, as a result of acetaminophen overdose.
Treatment: symptomatic, forced diuresis.
Symptoms (due terpine) disorders of the gastrointestinal tract, such as nausea, vomiting, pain in the stomach area.
Treatment: symptomatic.
pharmachologic effect
Pharmacological group:
ARI and “cold” symptoms Remedy (non-narcotic analgesic agent + psychostimulant agent + + alpha-agonists expectorant + vitamin).
Pharmacological properties:
Tabletki “Koldpekc” – kombinipovanny ppeparat. Papatsetamol okazyvaet obezbolivayuschee and zhapoponizhayuschee deyctvie, fenilefpin ymenshaet otek clizictyx obolochek cavity and pazyx noca, vcledctvie chego oblegchaetcya dyxanie, terpin hydrate enhances secretion of bronchial glands, promotes evacuation of mucus from airways kofein okazyvaet obschetoniziryyuschee deyctvie, ackorbinovaya kiclota (C vitamin) vocpolnyaet potrebnoct in vitamine C with “ppoctyde” and grippe.
Conditions of supply of pharmacies
Without recipe.
side effects
Side effects are classified according to organ system and frequency. The frequency of side effects is defined as follows: very often (greater than or equal to 1/10), often (greater than or equal to 1/100 and less than 1/10) times (greater than or equal to 1/1000 and less than 1/100), rare ( greater than or equal to 1/10 000 and less than 1/1000) and very rare (greater than or equal to 1/100 and less than 1/10 000 000). The recommended dosage is generally well tolerated drug. With prolonged use of hepatotoxic and nephrotoxic effects can occur in excess of the recommended dose. Excessive consumption of caffeine (coffee, tea) during treatment “Koldreks” can amplify manifestation of side effects caused by caffeine, such as insomnia, irritability and nervous tension, headache, palpitations, disturbances of the digestive system.
From the side of hematopoiesis:
Very rare: thrombocytopenia
Allergic reactions:
Very rarely, anaphylaxis, skin rash, urticaria, allergic dermatitis, angioedema, Stevens-Johnson syndrome
The respiratory system:
Very rare: bronchospasm in patients sensitive to aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs)
From the digestive system:
Very rare: nausea, vomiting, abnormal liver function
On the part of the central nervous system:
Very rarely: irritability, nervousness, dizziness, headache, insomnia
From the senses:
Very rare: mydriasis, an acute attack of glaucoma, in most cases, in patients with narrow-angle glaucoma
Cardio-vascular system:
Very rare: tachycardia, palpitations
From the urinary system:
Very rare: dysuria, urinary retention in patients with obstruction of the bladder outlet with prostatic hypertrophy.
In the event of any adverse reactions, contact your doctor.
special instructions
Peped ppiemom preparation “Koldreks” ppokoncyltipyytec c lechaschim vpachom: if ye By ppinimaete dpygie lekapctvennye formulations containing paracetamol, as well as other non-narcotic analgesics, NSAIDs (metamizole, acetylsalicylic acid, ibuprofen, etc.); By ppinimaete metoklopramid if ye, domperidon (primenyaemye lecheniya for nausea and vomiting) or kolectipamin (icpolzyemy for cnizheniya ypovnya xolectepina in kpovi).
BO IZBEZHAHIE TOKCICHECKOGO POPAZHEHIYA PECHEHI PAPATSETAMOL HE CLEDUET COCHETAT C PPIEMOM ALKOGOLHIX HAPITKOV, A TAKZHE PPIHIMAT LITSAM, CKLOHHIM K XPOHICHECKOMU POTPEBLENIYU Alcohol.
In case of occurrence of dizziness while taking the drug should refrain from performing potentially dangerous activities, requiring special attention and fast reactions (driving et al. Vehicles, work with the moving mechanisms and the like).
Storage conditions
Store in a dark place at a temperature not higher than 25 ° C.
Store in a nedoctypnom for detey mecte.
Dosing and Administration
Inside.
Adults and children over 12 years: single dose – 2 tablets. Repeated application of the drug may not earlier than 4 hours and not more than 4 times / day. The maximum daily dose should not exceed 8 tablets. The duration of treatment without consulting your doctor no more than 7 days.
It does not exceed this dose.
Do not take simultaneously with other paratsetamolsoderzhaschimi means, sympathomimetics (such as decongestants, agents that suppress appetite, amphetamine-like psychostimulant agents), with other agents for the relief of symptoms of “cold” and the flu.
It is necessary to avoid excessive intake of caffeine (coffee, tea and other beverages containing caffeine), as this may contribute to adverse side effects (see. Section “Side effects”).
If you are taking the drug symptoms persist, seek medical advice.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist