Cocarboxylase lyophilisates for solution for injection 50mg ampoules with 5 pcs rastv.voda 2ml

$2.57

Cocarboxylase lyophilisates for solution for injection 50mg ampoules with 5 pcs rastv.voda 2ml

5 in stock

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SKU: 0219790492 Categories: , , Tags: ,

Description

Composition
Active substance:
1 ampoule contains: cocarboxylase hydrochloride – 50 mg ;.
Excipients:
Sodium carbonate (sodium carbonate) – 8 mg.
Description:
Lyophilizate for preparation of solution for intravenous and intramuscular administration.
Product form:
Lyophilizate for preparation of solution for intravenous and intramuscular administration of 50 mg in ampoules. 10 ampoules with instructions for use, knife or lancet ampoule ampoule in a pack or box made of cardboard. 5 vials of preparation complete with 5 ampoules water for injection to 2 ml with instructions for use, knife or lancet ampoule ampoule in a pack or box made of cardboard. 5 vials of drug and 5 vials with water for injection to 2 ml in separate blisters. 1 with blisters and drug blisters 1 with water for injection with instructions for the use of a knife or lancet ampoule ampoule in a stack of cardboard. When packing ampoules having a ring or a break point for opening, knife or ampoule ampoule scarifier not invest. 5 vials of drug and 5 vials with water for injection to 2 ml in separate cluster outline packages. 1 cassette contour packaging with the preparation and packaging contour cassette 1 with water for injection with instructions for use in a stack of cardboard.
Contraindications
Hypersensitivity to the drug.
Dosage
50 mg
Indications
Kokarboksilazu administered in the adjuvant therapy of hepatic and renal failure, diabetic precoma and coma, diabetic ketoacidosis, chronic heart failure and cardiac arrhythmias, peripheral neuritis.
Children drug designate for the same indications. In newborns, the drug is also used in the complex treatment of conditions accompanied by hypoxia and acidosis, including neonatal asphyxia, hypoxic encephalopathy, circulatory failure, pneumonia, sepsis.
Interaction with other drugs
Kokarboksilaza strengthens the cardiac effects of cardiac glycosides and improve their portability.
pharmachologic effect
Pharmacological properties:
Cocarboxylase – coenzyme thiamine (vitamin B1), in an organism is phosphorylated to form the mono-, di-, and triphosphate esters, part of the enzymes that catalyze carboxylation and decarboxylation of alpha-keto acid, pyruvic acid.
Pregnancy and breast-feeding
Data on the safety of the drug when used by pregnant women are not available. Due to the insufficient number of study drug should not be prescribed to pregnant and lactating women.
Conditions of supply of pharmacies
P recipe.
side effects
Allergic reactions (urticaria, itching); Intramuscular – redness, itching, swelling (injection site).
Storage conditions
Store in a dark place at a temperature not higher than 20 C.
Dosing and Administration
Kokarboksilazu administered intramuscularly or intravenously (bolus or infusion).
The contents of ampoules (50 mg) was dissolved immediately prior to administration in 2 ml of water for injection. When intravenously administered volume adjusted to 10-20 ml and drip to 200-400 ml by adding 0.9% sodium chloride or dextrose (glucose).
When cardiac arrhythmias: 100-200 mg per day for 15-30 days.
In chronic heart failure: 50 mg for 2 hours before use of digitalis preparations 2-3 times a day.
In diabetes (ketoacidosis, coma), the daily dose is 100 mg.
In acute renal and hepatic failure administered intravenous bolus of 100-150 mg 3 times a day, or drip (previously dissolved in 5% dextrose (glucose) of 100-150 mg per day.
When peripheral neuritis administered intramuscularly at a dose of 50-100 mg per day for 1-1.5 months.
Babies are administered intramuscularly, intravenously (infusion or bolus). Depending on the severity of clinical symptoms and administered from 25 to 50 mg per day. The course of treatment from 3-7 to 15-30 days. Newborns are administered intravenously (slowly) 10 mg per 1 kg body weight once a day.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg
Manufacturer

Russia

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