Clotrimazole, quinacrine ointment for naruzhn.prim-I 1% 20g tube

$3.03

Clotrimazole, quinacrine ointment for naruzhn.prim-I 1% 20g tube

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SKU: 01848646975 Categories: , , Tag:

Description

Composition
Active substance:
100 g of ointment contain clotrimazole, based on 100% of the substance -1
Excipients:
Propylene glycol 12.5 g methyl parahydroxybenzoate (Nipagin) – 0.2 g of succinic acid, 0.5 g of sodium benzoate – 6 g, wax emulsion – 3 g Castor oil – 14 g, methylcellulose – 3 g Distilled monoglycerides 1.5 g purified water – 100 g
Description:
Ointment of white or off-white color with a weak specific smell.
Product form:
Ointment for external application of 1%. 20 g of aluminum into a tube. Each tube together with instructions for use placed in a pile of cardboard.
Contraindications
Hypersensitivity to kpotrimazolu or excipients, pregnancy (I term), children up to 2 years.
Carefully
Lactation, pregnancy (II and III trimester).
Dosage
1 %
Indications
-gribkovye skin diseases including skin folds and the stop induced by dermatophytes, yeast (Candida spp.), molds and other fungi and pathogens sensitive to clotrimazole dermatomycosis, dermatophytosis, trichophytosis, tinea, mikrosporiya, candidiasis, fungal interdigital erosion, fungal paronychia, -mikozy complicated by secondary pyoderma, in the complex therapy, -otrubevidny zoster, pityriasis versicolor, erythrasma.
Interaction with other drugs
Amphotericin B, nystatin, natamycin reduce the effectiveness of clotrimazole while their application.
Overdose
Low systemic absorption of the active ingredient of the drug when applied externally makes practically impossible overdose.
pharmachologic effect
Pharmacological group:
Antifungal agent.
Pharmacodynamics:
Antifungal agent from the group of imidazole derivatives for topical use, reduces the synthesis of ergosterol, which is part of the microbial cell membrane wall, and causes a change in its structure and properties.
At low concentrations fungistatic effect and large (more than 20 micrograms / ml) – fungicide, not only in proliferating cells. The fungicidal concentrations interacts with mitochondrial and peroxidase enzymes, resulting in increased concentrations of hydrogen peroxide up to a toxic level, which also contributes to the destruction of fungal cells.
Active against pathogenic dermatophyte (Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, Microsporum canis), yeasts and fungi (Candida spp., Torulopsis glabrata, Rhodotorula spp., Pityrosporum orbiculare).
Pharmacokinetics:
Poorly absorbed through the skin and mucous membranes, and almost no systemic action. Is accumulated in the stratum corneum of the epidermis, it penetrates the nail keratin. The concentration in the deep layers of the epidermis is higher than the minimum inhibitory concentration for dermatophytes.
Pregnancy and breast-feeding
Carefully
Lactation, pregnancy (II and III trimester).
Conditions of supply of pharmacies
Without recipe.
side effects
Local reactions burning, swelling, irritation and scaling of the skin, paresthesia, erythematous rash, blisters. Allergic reactions pruritus, urticaria.
special instructions
Avoid contact with eye mucosa. Patients with hepatic insufficiency should periodically monitor liver function. When signs of hypersensitivity or irritation of the treatment was stopped. If no effect within 4 weeks should confirm the diagnosis. Children should avoid use on larger surfaces.
Storage conditions
In a dry, dark place at a temperature not higher than 15 ° C. Keep out of the reach of children.
Dosing and Administration
Outwardly. Adults with no other assignments is recommended to apply the ointment 2-3 times a day with a thin layer on a pre-cleaned and dry the affected skin. A single dose on a surface area with palm size – column ointment 5 mm. For successful treatment it is important to regularly use ointment. Duration of therapy is individual and depends on the severity and localization of the disease. To achieve complete recovery should not stop treatment ointment immediately after the disappearance of symptoms of acute inflammation or subjective complaints. Duration of therapy should be on average about 4 weeks. Pityriasis versicolor cured, mainly for 1-3 weeks and erythrasma for 2-4 weeks. Fungal diseases of the skin of the feet is recommended to continue treatment for about 2 weeks after the relief of symptoms of the disease. In children 2 years of drug use in the above-mentioned doses.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg
Manufacturer

QUINACRINE INN

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