Celestoderm In-0.1% cream 15 g

Description

Composition
Active substance:
1 g of cream contains: Betamethasone 17-valerate – 1.22 mg (equivalent to 1 mg of betamethasone) ;.
Excipients:
White Soft Paraffin – 150.0 mg, cetostearyl alcohol – 72.0 mg Liquid paraffin – 60.0 mg, macrogol cetostearyl ether – 22.5 mg, phosphoric acid and sodium hydroxide – q.s. (As a 5% solution in an amount necessary to establish pH), sodium dihydrogen phosphate dihydrate – 3.39 mg (corresponding to 3.0 mg of sodium dihydrogen phosphate monohydrate), chlorocresol – 1.0 mg Purified Water – q.s. and 1.0 g
Description:
Uniform cream white with a soft consistency, free of visible particles.
Product form:
Cream for external use of 0.1%. 15 g or 30 g of the aluminum tubes coated with epoxy resin varnish and closing membrane and the screw cap. According to one tube together with instructions for use in a cardboard package.
Contraindications
Hypersensitivity to any component of the drug.
Pregnancy (high dose, long-term treatment).
Lactation.
Children’s age – up to 6 months.
Dosage
1 mg / g
Indications
Inflammatory skin diseases amenable glucocorticosteroid (GCS) therapy, eczema (atopic, children, nummular), contact dermatitis, seborrheic dermatitis, atopic dermatitis, solar dermatitis, exfoliative dermatitis, radiation dermatitis, intertriginous dermatitis, psoriasis, and actinic anogenital pruritus.
Interaction with other drugs
Any drug interactions Celestoderm-B with other drugs is not registered.
Overdose
Symptoms. Excessive or prolonged use of local corticosteroids can cause inhibition of the function of the pituitary-adrenal system, which can cause the development of secondary adrenal insufficiency and the emergence of symptoms of Cushing, including Cushing’s syndrome.
Treatment. Displaying appropriate symptomatic treatment. Acute symptoms of Cushing’s usually reversible. If necessary, correction shown electrolyte imbalance. In the case of chronic toxic recommended the phasing out
GCS.
pharmachologic effect
Pharmacological group:
Glucocorticosteroids for local use.
Pharmacological properties:
Betamethasone protivoallergicheckoe and anti-inflammatory action by inhibition of cytokine release and inflammatory mediators, reduction of arachidonic acid metabolism, inducing formation lipokortinov having antiedematous activity reduction in vascular permeability.
Microdispersion of glucocorticosteroid (GCS) in lean, odorless, without leaving marks on clothes easily washed cream base provides effective skin penetration and a rapid onset of action.
Pregnancy and breast-feeding
Due to the fact that the safety of local corticosteroids in pregnant women has not been established, the purpose of this class of drugs in pregnancy is justified only if the benefit to the mother clearly outweighs the potential harm to the fetus. this group of drugs should not be used in pregnant women or in large doses for a prolonged time.
Since hitherto not been established whether the topical application of corticosteroids and systemic absorption into breast milk, should discontinue breastfeeding or use of the drug, given the extent to which its application is necessary for the mother.
Conditions of supply of pharmacies
Without recipe.
side effects
In the application of topical corticosteroids have been observed following adverse effects: burning, irritation and dryness, folliculitis, hypertrichosis, ugrevidnye eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae and miliaria.
special instructions
In the absence of the effect of treatment for 2 weeks advised to consult the physician with a view to the possible diagnosis.
If use of the drug noted irritation or hypersensitivity reaction, treatment should be discontinued and the patient to choose the appropriate therapy. When the secondary bacterial or fungal infection should designate corresponding medicaments. In case of absence at the same rapid positive effect, the use of corticosteroids should be discontinued until such time until you have eliminated all signs of infection.
Any side effects of systemic corticosteroids, including suppression of adrenocortical function may be observed when using local corticosteroids, especially in children.
Systemic absorption of local corticosteroids improved by their long-term use in the treatment of large body surface or when using closing dressings, as well as in children.
Celestoderm-B is shown for external use only and is not intended for use in ophthalmology.
Use in pediatric patients.
Cream Celestoderm-B can be used to treat children under the age of 6 months.
Children may be more receptive to the use of corticosteroids include causing inhibition of the hypothalamic-pituitary-adrenal (HPA) than older patients, due to the increased absorption of the drug associated with a greater magnitude relations have surface area and weight.
In children, taking local corticosteroids, note the following side effects: inhibition of the function of the HPA system, Cushing’s syndrome, linear growth retardation, retarded weight gain, increased intracranial pressure. Symptoms of depression of adrenocortical function in children include decreased levels of cortisol in plasma and the lack of response to ACTH stimulation. Increased intracranial pressure manifested bulging fontanelle, headache, bilateral papilledema.
Effects on ability to drive and use machines.
It does not reveal any effect of the drug Celestoderm-in on the ability to drive and use machines.
Storage conditions
In the reach of children.
Store at a temperature not higher than 25 ° C.
Dosing and Administration
Outwardly.
Cream Celestoderm-B should be applied to a thin layer to affected area 1-3 times a day, depending on the severity of the condition. In most cases, to achieve the effect is enough applying 1-2 times per day.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist