Castor oil 30ml vial

Description

Composition
Active substance:
100% castor oil.
Product form:
Bottle 30 g or 50 g.
Contraindications
Idiosyncrasy; chronic constipation; acute inflammatory bowel diseases (including appendicitis); mechanical intestinal obstruction; abdominal pain of unknown origin; intestinal and uterine bleeding; acute and chronic glomerulonephritis; tubulointerstitial nephritis; poisoning fat-soluble toxins (including gasoline, carbon tetrachloride, an extract of male fern); pregnancy; lactation; children’s age (12 years)
The use of castor oil in children under 12 years of age is not recommended due to the high sensitivity to the children’s intestinal irritant substances and dangerous dehydration development.
Indications
For intake: constipation.
For external use in ointments, balms: burns; wound; ulcers; dry skin; dandruff; to strengthen the hair.
Interaction with other drugs
When applied simultaneously reduces the absorption of fat-soluble vitamins A, D and K. At doses up to 4 g / day increases the absorption of fat-soluble drugs – extract of male fern, mebendazole, griseofulvin, probucol.
While the use of saline laxatives possible sharp increase laxative effect.
M-anticholinergic agents (atropine sulphate, platifilin pirenzepine), spasmolytics (papaverine, drotaverine) weaken the effect of castor oil.
Anticholinesterases (neostigmine, pyridostigmine, rivastigmine) and glycerol increase the laxative effect of castor oil.
It enhances the action of agents that stimulate the contractile activity of the myometrium (metilergometrina, ergometrine, oxytocin, prostaglandins) up to a threat of uterine rupture during labor.
For topical application increases the percutaneous absorption of drugs, applied together with it to the skin.
pharmachologic effect
Pharmacological group:
The laxative of plant origin.
Pharmacodynamics:
The mechanism of action is associated with castor oil released from it in the lumen of the duodenum ritsinolovoy acid. At a concentration of 0.5 mmol / l ritsinolovaya acid irritates receptors throughout the intestine and stops the Na + / K + / 2Cl – conveyors, resulting in stops absorption of electrolytes and second delayed absorption of water. At concentrations of more than 2 mmol / l ritsinolovaya acid enhances the water secretion into the intestinal lumen.
Under the influence of castor oil increases the volume of intestinal contents, increased bowel motility, accelerates emptying. Remaining in the intestines oil facilitates the advancement of stool through the large intestine. The laxative effect develops within 2 – 6 h after administration of the oil and diminishes after a bowel movement.
During stimulation of intestinal receptors castor oil stimulates the spinal cord reflex center coordinates the contractile activity of the myometrium. As a result of castor oil increases the contractions of the uterus during pregnancy.
Pharmacokinetics:
After oral administration in the alkaline environment of the duodenum in the presence of bile under the influence of lipase oil formed ritsinolovaya acid. Absorption ritsinolovoy acid inversely proportional to the dose. When administered to an oil at a dose of 4 g absorbance ritsinolovoy acid is about 100% at a dose of 50 g is absorbed only 36% (the remainder of the acid is excreted in feces within 24 hours) at a dose of 60 g fraction of absorbed acid is only 10 %. Ritsinolovoy acid absorption speed is half the speed of absorption of oleic acid. For the development of laxative intake effect requires at least 10 g of an oil.
Absorbing part ritsinolovoy acid undergoes beta-oxidation in the liver and skeletal muscle and is included in metabolic processes.
Pregnancy and breast-feeding
The use of castor oil is contraindicated in pregnancy due to the possibility of its early termination. Application in the III trimester of pregnancy is possible only for health reasons. If necessary, use during lactation should stop breastfeeding for the duration of the treatment.
Conditions of supply of pharmacies
Without recipe.
side effects
Abdominal pain, nausea; digestive disorders, enterocolitis during repeated use; hypovitaminosis A and D during repeated use; rush of blood to the pelvic organs; addictive with repeated application.
special instructions
Effects on ability to drive vehicles and management mechanisms. During the reception, castor oil is recommended not to operate a motor vehicle, you should refrain from other activities of the operator in connection with the possible violation of attention concentration during the onset of the effect.
Sensible use. It is not recommended to use castor oil as a purgative more than 3 days, as can be disrupted digestion and absorption of vitamins A and D, with the development of appropriate hypovitaminosis. Never use of castor oil in the treatment of drug obtained from male fern, since with the possibility of their systemic absorption and development of neurotoxicity.
Storage conditions
In the dark place at a temperature not exceeding 25 C. Keep out of reach of children.
Dosing and Administration
Inside the adult prescribe 15-30 grams of oil or capsules 15-30, children – 5-15 g of oil or capsules 5-10. Capsules are taken for 30 minutes.
To enhance the growth of hair was prepared a solution consisting of 10 g of castor oil and 100 ml of 96% ethanol, which is rubbed into the scalp.
In the treatment of burns and skin wounds topically administered in the form of emulsions boltushek and distilled water 1 – 2 times a day under the bandage.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist